Manufacturer: Gujarat Terce Laboratories Ltd
Salt Composition : Ceftriaxone(250mg), Tazobactum(31.25mg)
Vial of 5ml Injection
(Inclusive of all taxes)
Cesafe TZ 250 mg/31.25 mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.
Ceftriaxone, a bactericidal antimicrobial, inhibits bacterial cell wall synthesis of actively dividing cells by binding to one or more penicillin-binding proteins (PBPs). These proteins are associated with the bacterial cell membrane and probably serve in synthesis.
Within 30 min of infusion, piperacillin/tazobactam achieves 16-85% of plasma concentrations in skin, muscle, lung, gallbladder, and intestinal mucosa. Plasma and tissue levels remain above the MIC90s of major pathogens for 2 h post administration
Pharmacokinetics. Absorption: Ceftriaxone can be administered intravenously and intramuscularly, and the drug is completely absorbed. It is not available orally. Distribution: Ceftriaxone penetrates tissues and body fluids well, including cerebrospinal fluid to treat central nervous system infections
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cesafe TZ
Diarrhea
Increased liver enzymes
Allergic reaction
Rash
diarrhea from an infection with Clostridium difficile bacteria.
a type of blood disorder where the red blood cells burst called hemolytic anemia.
liver problems.
disease of the gallbladder.
severe renal impairment.
yellowing of the skin in a newborn child.
Cesafe TZ 250 mg/31.25 mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol with Cesafe TZ 250 mg/31.25 mg Injection does not cause any harmful side effects.
Cesafe TZ 250 mg/31.25 mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
CEFTRIAXONE+TAZOBACTAM belongs to a class of medication called 'antibiotics' used to treat several bacterial infections of the urinary tract, blood, bones and joints, heart, brain, chest, ears, skin or soft tissues. The bacterial infection is a condition in which harmful bacteria grows in the body and cause infection
Drug-Drug Interaction: CEFTRIAXONE+TAZOBACTAM may interact with a blood thinner (heparin), drugs used to lower high uric acid levels (probenecid), neuromuscular blocking agent (vecuronium), anticancer drug (methotrexate), water tablet (furosemide) and antibiotics (chloramphenicol, gentamicin, streptomycin)
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Store below 30°C
If you miss a dose of Cesafe TZ 250 mg/31.25 mg Injection, please consult your doctor.
Consult a doctor before taking any medicines
You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Cesafe TZ 250 mg/31.25 mg Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking Cesafe TZ 250 mg/31.25 mg Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How long does Cesafe TZ 250 mg/31.25 mg Injection takes to work?
Usually, Cesafe TZ 250 mg/31.25 mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Q. What if I don't get better after using Cesafe TZ 250 mg/31.25 mg Injection?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
