Manufacturer: Lupin Ltd
Salt Composition : Cetrorelix(0.25mg)
Cetronext 0.25mg Injection is injecting directly into the skin under the supervision of a doctor. Do not self administer the injection. Your doctor or nurse may help you to know the best way to inject the medicine at home. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.
Cetrorelix binds to the gonadotropin releasing hormone receptor and acts as a potent inhibitor of gonadotropin secretion. It competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner.
Cetrorelix, LH, follicle-stimulating hormone, estradiol, and progesterone were determined. Results: Cetrorelix pharmacokinetics were described by a 2-compartment model with a terminal half-life of 56.9 +/- 27.1 hours. Mean shift in LH surge was by 4.1, 7.5, and 9.3 days with the 1-, 3-, and 5-mg doses, respectively
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cetronext
Nausea
Ovarian hyperstimulation syndrome
Injection site reactions (pain, swelling, redness)
Itching
Irritation
Vomiting
Lower abdominal pain
Hypersensitivity to cetrorelix acetate, extrinsic peptide hormones or mannitol.
Known hypersensitivity to GnRH or any other GnRH analogs.
Known or suspected pregnancy, and lactation (see PRECAUTIONS).
Severe renal impairment
Cetronext 0.25mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Caution is advised when consuming alcohol with Cetronext 0.25mg Injection. Please consult your doctor.
Cetronext 0.25mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Indicated for the inhibition of premature LH surges in women undergoing controlled ovarian stimulation. Ovarian stimulation therapy with gonadotropins (FSH, hMG) is started on cycle Day 2 or 3.
This medication is used by women having certain fertility treatments (controlled ovarian stimulation). Cetrorelix is usually used in combination with other hormones (FSH and hCG). It works by blocking the release of a certain hormone (luteinizing hormone). Cetrorelix stops eggs from being released too early and gives the eggs time to grow properly.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Cetronext 0.25mg Injection, please consult your doctor.
Consult a doctor before taking any medicines
Cetronext 0.25mg Injection helps prevent premature ovulation in women undergoing assisted reproduction treatments such as IVF.
It is given as an injection under the skin (subcutaneously), preferably of the upper leg.
Inform your doctor immediately if you get very dizzy, faint, vomit, or have diarrhea while using this medicine. These could be symptoms of ovarian hyperstimulation syndrome (OHSS).
Do not use this medicine if you are already pregnant or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What is Cetronext 0.25mg Injection and for what it is used for?
Cetronext 0.25mg Injection is an injectable preparation, which contains the active substance Ganirelix. It is used in women undergoing certain fertility treatments. It acts by blocking the release of luteinizing hormone (LH) thus preventing eggs from being released too early and gives the eggs time to grow properly. It is usually used in combination with other medicines.
Q. How and in what dose can it be used?
It is given as an injection, only at the hospital or clinic by the medical healthcare professional. The patient may be monitored regularly for the follicular development. The treatment duration depends on the ovarian response of the patient.
Q. What may be the possible side effects associated with it?
The most common side effect is local site reaction (redness of skin with or without swelling). You may also feel a headache or nausea. However, these effects are temporary, if these persist consult with your doctor. In addition, conditions like ovarian hyperstimulation syndrome (OHSS), and multiple births or birth defect, may also be associated with the use of this medicine.
