Manufacturer: RPG Life Sciences Ltd
Salt Composition : Gefitinib(250mg)
Chemofit 250mg Tablet can be taken with or without food, but better to have it same time every day for better results. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Gefitinib is an EGFR tyrosine kinase inhibitor. It works by binding to the intracellular enzyme (tyrosine kinase) of the EGFR to directly block signals turned on by triggers outside or inside the cell
A high clearance of gefitinib might result in drug resistance by lowering drug concentration. The enhanced efflux and decreased uptake by transporters were important resistance mechanisms. The transporters involved in pharmacokinetics of gefitinib consist of the ATP-binding cassette and the solute carrier superfamily
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Chemofit
Diarrhea
Dry skin
Loss of appetite
Nausea
Rash
Stomatitis (Inflammation of the mouth)
Vomiting
Weakness
Weight loss
lung disease (such as pulmonary fibrosis), severe kidney disease, eye problems, stomach/intestinal ulcers, other stomach/intestinal problems (such as diverticulitis, blockage, bowel disease), smoking, cancer
Chemofit 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Chemofit 250mg Tablet.
Chemofit 250mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
IRESSA is indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations as detected by an FDA-approved test [see Clinical Studies
Take Chemofit 250 mg Tablet as instructed by the doctor. Do not consume larger quantities than prescribed. It should be used as prescribed by the doctor to prevent the spread of cancer to other parts of the body. Discontinue the treatment if any symptoms of allergic skin reactions appear.
Do not chew, crush or break it. Chemofit 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Chemofit 250mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines
Chemofit 250mg Tablet helps treat non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
Take it with or without food, preferably at the same time each day.
Do not take antacids (to reduce the acid level of your stomach) 2 hours before or 1 hour after taking this medicine.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Inform your doctor if you develop ulceration in your mouth, changes in your vision or if you experience a worsening cough, shortness of breath, or breathing difficulties while taking this medicine.
Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Chemofit 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
