Manufacturer: Micro Labs Ltd
Salt Composition : Paracetamol, Phenylpropanolamine, Cetirizine
Chest Kold Tablet may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor. It is usually best taken with food otherwise it may upset your stomach. Do not take more or use it for longer than recommended.
Chest Kold Tablet is a common painkiller used to treat aches and pains. It works by blocking chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches
The pharmacokinetics of cetirizine have been found to increase linearly with dose across a range of 5 to 60 mg. Its Cmax following a single dose has been found to be 257 ng/mL for 10 mg and 580 ng/mL for 20 mg
It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates
Phenylephrine is readily and completely absorbed from the gastro-intestinal tract after oral administration . It is subject to extensive presystemic metabolism in the gut wall and therefore has a systemic bioavailability of approximately 40% relative to intravenous dosing.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Chest Kold
Nausea
Vomiting
Insomnia (difficulty in sleeping)
Headache
Constipation
Itching
Contraindications : MAO inhibitor use w/in 14 days, Urinary retention, CAD, Uncontrolled or severe HTN. Caution if HTN, arrhythmias, cardiovascular disease, diabetes mellitus, angle-closure glaucoma, hyperthyroidism, renal impairment, PKU (phenylalanine-containing forms), in pts <6 yo.
caloric undernutrition.
acute liver failure.
liver problems.
a condition where the body is unable to maintain adequate blood flow called shock.
acetaminophen overdose.
acute inflammation of the liver due to hepatitis C virus.
Cetirizine is contraindicated in anyone with a known hypersensitivity to it or any of its ingredients. Cetirizine is also contraindicated in anyone with a known hypersensitivity to hydroxyzine, as cetirizine is a metabolite of hydroxyzine
Chest Kold Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Chest Kold Tablet.
Information regarding the use of Chest Kold Tablet during breastfeeding is not available. Please consult your doctor.
The FDA-approved indication for intravenous (IV) phenylephrine hydrochloride is for increasing blood pressure in adults with clinically significant hypotension resulting primarily from vasodilation in such settings as septic shock or anesthesia
Paracetamol is a mild analgesic and antipyretic, and is recommended for the treatment of most painful and febrile conditions, for example, headache including migraine, toothache, neuralgia, colds and influenza, sore throat, backache, rheumatic pain and dysmenorrhoea
Cetirizine is indicated for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria in adults and children 6 months of age and older. It markedly reduces the occurrence, severity, and duration of hives and significantly reduces pruritus
iobenguane
isocarboxazid.
linezolid.
phenelzine.
procarbazine.
selegiline transdermal.
tranylcypromine
Despite its frequent coadministration with other drugs and widespread use, very few clinically significant drug interactions have been documented with paracetamol. Drugs that alter gastric emptying can alter paracetamol pharmacokinetics, but this does not result in toxicity in therapeutic use
bosutinib.
clobazam.
crizotinib.
daclatasvir.
eliglustat.
hyaluronidase.
lomitapide.
lurasidone.
Do not chew, crush or break it. Chest Kold Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Chest Kold Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Paracetamol
Paracetamol should be taken with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
Do not take indigestion remedies (antacids) within 2 hours of taking Paracetamol.
Avoid consuming alcohol while taking this medicine as it can increase your risk of stomach problems.
Inform your doctor if you have liver disease as your dose may need to be adjusted.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
Phenylpropanolamine
Do not continue phenylpropanolamine for more than 7 days if your condition does not improve or if you have high fever.
Tell your doctor if you have high blood pressure, heart problems, liver or kidney disease, diabetes, prostate enlargement or visual problems due to increased pressure in the eyes (glaucoma).
Seek immediate medical attention and discontinue medication if you experience difficulty in breathing, sudden swelling or skin reactions, fits, rapid heartbeat or hallucinations.
Use with caution if you are a woman or an elderly patient. Woman may be at a higher risk of haemorrhagic stroke (bleeding in the brain).
Avoid driving or operating machinery if you feel dizzy or drowsy after taking phenylpropanolamine.
Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Do not take if allergic to phenylpropanolamine or any of its ingredients.
Cetirizine
Your doctor has prescribed Cetirizine to help relieve allergy symptoms such as itching, swelling, and rashes.
It's much less likely to make you feel sleepy than other similar medications.
It is okay to take Cetirizine with most other medications as it has few drug interactions.
Use caution while driving or doing anything that requires concentration as Cetirizine can cause dizziness and sleepiness.
Do not drink alcohol while taking Cetirizine as it may cause increased sleepiness.
Stop taking Cetirizine at least three days before taking an allergy test as it can affect the test results.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Chest Kold Tablet may be taken with or without food, but it is better to take it at a fixed time.
Paracetamol
Q. What if I vomit after taking Paracetamol?
If you vomit in less than 30 minutes after having a dose of Paracetamol tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.
Q. When will I feel better after taking the Paracetamol?
Usually, you will start feeling better after about half an hour of taking a Paracetamol.
Q. How often can I take the Paracetamol?
You should only take four doses of Paracetamol in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take Paracetamol for more than 3 days without consulting a doctor first.
Q. Does Paracetamol make babies sleepy?
No, Paracetamol does not make babies sleepy. It is a pain-relieving medicine that is also used to control high fever.
Phenylpropanolamine
Q. Is phenylpropanolamine the same as phenylephrine?
Phenylpropanolamine and phenylephrine are different drugs belonging to the same class of medications (nasal decongestants). Both are used to relieve blocked nose or sinuses caused by common cold and seasonal nasal allergies (hay fever)
Q. Does Phenylpropanolamine cause stroke?
Phenylpropanolamine has shown to increase the risk of hemorrhagic stroke (bleeding in the brain). Women are at a higher risk.
Q. Is Phenylpropanolamine a controlled substance?
Phenylpropanolamine is a controlled substance since it can be used for manufacturing of illegal drugs
Q. Is Phenylpropanolamine still on the market?
Phenylpropanolamine is banned in India due to increased risk of haemorrhagic stroke (bleeding in the brain) and is no longer marketed in India
Cetirizine
Q. Does Cetirizine make you tired and drowsy?
Yes, Cetirizine can make you feel tired, sleepy, and weak. If you have these symptoms, you should avoid driving or operating heavy machinery.
Q. Is Cetirizine a steroid? What is it used for?
Cetirizine is an anti-allergic medication, not a steroid. It relieves the symptoms of allergy. It is used to relieve runny nose, sneezing and redness, itching, and watering of the eyes caused by hay fever or seasonal allergies. It also relieves similar symptoms caused due to allergies to substances, such as dust mites, animal dander, and mold. It is also used to treat symptoms of hives, including itching and rash.
Q. How long does it take for Cetirizine to work?
You will notice an improvement within an hour of taking Cetirizine. However, it may take a little longer to notice the full benefits.
Q. Can I take Cetirizine and Fexofenadine together?
Sometimes the doctor may advise you to take two different antihistamines together if you are being treated for a severe itchy rash. If you are taking Cetirizine during the daytime, your doctor may prescribe another antihistamine for the night which causes sleepiness, especially if the itch makes it difficult for you to sleep. Do not take two antihistamines together unless recommended by your doctor.
