Manufacturer: Lupin Ltd
Salt Composition : Sacubitril(24mg), Valsartan(26mg)
Cidmus 50mg Tablet can be taken with or without food but is best taken at the same time(s) each day. Swallow it as a whole with water. Your dose, and how often you take it, will be decided by your doctor and may change depending on how well you respond to the medicine. Keep taking the tablets regularly, as they have been prescribed, and try not to miss doses to get the most benefit. Do not stop taking them, even if you are feeling well. These tablets are preventing future harm.
The sacubitril/valsartan drug inhibits neprilysin and blocks angiotensin II type-I receptor, increasing the levels of peptides degraded by neprilysin. Valsartan inhibits the effects of angiotensin II by blocking the AT1 receptor and by inhibiting the release of angiotensin II-dependent aldosterone
Absorption of sacubitril/valsartan and conversion of sacubitril (prodrug) to sacubitrilat (neprilysin inhibitor) was rapid with maximum plasma concentrations of sacubitril, sacubitrilat, and valsartan (angiotensin receptor blocker) reaching within 0.5, 1.5-2.0, and 2.0-3.0 h, respectively.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cidmus
Cough
Dizziness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Altered levels of potassium in blood
Decreased red blood cell count
Decreased blood pressure
Hypoglycemia (low blood glucose level)
Diarrhea
Fainting
Headache
Nausea
Stomach pain
Vertigo
Weakness
Cidmus 50mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Cidmus 50mg Tablet.
Cidmus 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
diabetes.
angioedema.
hypotension.
CHF.
hyperkalemia.
renal artery stenosis.
renal impairment.
renal/liver disease.
Do not chew, crush or break it. Cidmus 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Cidmus 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed Cidmus 50mg Tablet for the treatment of of long-lasting (chronic) heart failure.
You should continue to stay active (light walking, stretching) and eat a healthy, low sodium diet along with taking this medication.
To reduce the chances of feeling dizzy, rise slowly if you have been sitting or lying down.
It may cause the level of potassium in your blood to go up. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
Inform your doctor if you have a history of liver or kidney diseases.
Do not take Cidmus 50mg Tablet if you are pregnant or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cidmus 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Who should avoid taking Cidmus 50mg Tablet?
Patients who are allergic to any of its components should avoid Cidmus 50mg Tablet. Also, those who are allergic to the use of ACE inhibitors or ARBs should avoid using this medicine. It should not be used along with other antihypertensive medicines like ACE inhibitors or ARBs. Do not take it for at least 36 hours before or after you take an ACE inhibitor medicine. If you are not sure, consult your doctor.
Q. What should I tell my doctor before taking Cidmus 50mg Tablet?
Tell your doctor about all of your medical conditions, including liver or kidney disease, history of facial swelling (angioedema). Inform him if you are pregnant or are breastfeeding. Also, let your doctor know about all medicines you are taking, especially potassium supplements or its medicine salt, painkillers, blood pressure or heart failure medicines (such as ACE inhibitor, ARBs or Aliskiren).
Q. Can I use Cidmus 50mg Tablet in pregnancy?
No, Cidmus 50mg Tablet should be avoided in pregnancy. Its use can cause injury or even endanger the life of the baby. If you become pregnant while using Cidmus 50mg Tablet, stop using it and contact your doctor immediately.
Q. How would I know if I have high potassium levels?
Your doctor will check your blood potassium levels periodically to detect high potassium levels (hyperkalemia). Make sure that you do not miss any scheduled appointments with the doctor.
