Manufacturer: Cadila Pharmaceuticals Ltd
Salt Composition : Cilnidipine(10mg), Chlorthalidone(6.25mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Ciledge CT 6.25mg Tablet should be taken with food preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.
Cilnidipine acts on the L-type calcium channels of blood vessels by blocking the incoming calcium and suppressing the contraction of blood vessels, thereby reducing blood pressure
Chlorthalidone inhibits sodium reabsorption at the level of the distal convoluted tubule and thus chloride via inhibition of the Na/Cl symporter. By removing sodium reabsorption at this location, the distal convoluted tubule of the nephron retains a higher sodium content
Cilnidipine presents a very rapid absorption with a maximum peaked concentration after 2 hours. Its distribution tends to be higher in the liver as well as in kidneys, plasma and other tissues. Cilnidipine does not present a high accumulation in the tissue after repeated oral administration
Chlortalidone is slowly absorbed from the gastrointestinal tract after oral ingestion. It has a long half-life and therefore a prolonged diuretic action, which results in continued diuretic effects despite a skipped dose.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ciledge CT
Glucose intolerance
Sleepiness
Ankle swelling
Headache
Flushing (sense of warmth in the face, ears, neck and trunk)
Tiredness
Palpitations
Nausea
Increased blood uric acid
Decreased potassium level in blood
Altered blood lipid level
Cilnidipine is contraindicated in patients with known hypersensitivity (e.g., anaphylaxis or angioedema) to Cilnidipine or any other component of this product. Hypotension, poor cardiac reserve, heart failure. Sudden withdrawal may exacerbate angina
Advanced chronic kidney disease.
Orthostatic hypotension.
Syncope.
Geriatric population (age greater than 65 due to risk of hyponatremia)
Pregnancy.
Hypercalcemia.
Severe hyperuricemia or gout.
Ciledge CT 6.25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Ciledge CT 6.25mg Tablet may cause excessive drowsiness with alcohol.
Information regarding the use of Ciledge CT 6.25mg Tablet during breastfeeding is not available. Please consult your doctor.
Cilnidipine is a calcium antagonist or calcium channel blocker prescribed to treat the high blood pressure in patients with essential hypertension
Chlorthalidone is indicated in adults as adjunctive therapy in edema associated with heart failure, cirrhosis of the liver, and renal disease, including nephrotic syndrome.
Acebutolol Acebutolol may increase the arrhythmogenic activities of Cilnidipine.
Aceclofenac The risk or severity of hyperkalemia can be increased when Aceclofenac is combined with Cilnidipine.
anuria.
electrolyte losses.
liver disease.
lupus erythematosus.
renal function disorders.
asthma.
diabetes.
hyperlipidemia.
Do not chew, crush or break it. Ciledge CT 6.25mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Ciledge CT 6.25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Ciledge CT 6.25mg Tablet helps in the treatment of high blood pressure.
It also lowers your risk of stroke and heart attack.
Take it in the morning with breakfast to avoid getting up at night to urinate.
It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
It may cause you to feel lightheaded or weak especially when you stand up (orthostatic hypotension). Rise slowly if you have been sitting or lying down.
It may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this medicine.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ciledge CT 6.25mg Tablet is to be taken with food.
