Cimivir 400mg Tablet (28'S)

Manufacturer: Biocon

Salt Composition : Sofosbuvir(400mg)


Cimivir 400mg Tablet should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It should be taken with food, preferably at a fixed time. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.



Basic Information

Mechanism Of Action

Cimivir 400mg Tablet works by preventing the HCV virus from multiplying in your body. It helps control the infection and makes the immune system work better. This lowers your chances of getting complications and improves your quality of life.

Pharmacokinets

Sofosbuvir is rapidly absorbed and eliminated from plasma (T max: 0.8-1 h; t 1/2: 0.5 h). The peak plasma concentrations for GS-331007 are achieved between 3.5 and 4 h post-dose; the elimination t 1/2 for GS-331007 is 27 h.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cimivir

Fatigue

Nausea

Headache

Insomnia (difficulty in sleeping)

Anemia (low number of red blood cells)

Contra Indications

General Information. ...

Pregnancy. ...

Breast-feeding. ...

Contraception requirements, male-mediated teratogenicity, pregnancy testing, reproductive risk. ...

Renal failure, renal impairment. ...

Hepatic disease. ...

Hepatitis C and HIV coinfection. ...

Hepatitis B exacerbation.


Pregnancy Related Information

Cimivir 400mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Cimivir 400mg Tablet. Please consult your doctor.


Breast Feeding Related Information

Cimivir 400mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

SOVALDI is indicated for the treatment of chronic HCV genotype 2 or 3 infection in pediatric patients 3 years of age and older without cirrhosis or with compensated cirrhosis for use in combination with ribavirin 

Interactions

Other medications can affect the removal of sofosbuvir from your body, which may affect how sofosbuvir works. Examples include rifamycins (such as rifampin, rifabutin), St. John's wort, tipranavir/ritonavir, drugs used to treat seizures (such as carbamazepine, phenobarbital, phenytoin, primidone), among others

Typical Dosage

Do not chew, crush or break it. Cimivir 400mg Tablet is to be taken with food.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Cimivir 400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Cimivir 400mg Tablet is used along with other medications for the treatment of chronic hepatitis C virus (HCV) infection.

Do not skip any doses and finish the full course of treatment even if you feel better.

It has fewer side effects compared to other similar medications.

Take it with food, preferably at the same time everyday.

You will usually need to take this medicine every day for either 12 or 24 weeks.

It may cause fatigue, dizziness, and blurred vision. Don't drive or do anything requiring concentration until you know how it affects you.

Your doctor may monitor your liver function and the amount of hepatitis C virus in your body regularly.

Do not stop taking Cimivir 400mg Tablet without your doctor’s advice.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cimivir 400mg Tablet is to be taken with food.


FAQs

Q. How does Cimivir 400mg Tablet work?

Cimivir 400mg Tablet.tops viral replication and thus decreases the amount of Hepatitis C virus in the body thereby resulting in less liver damage and improved liver function

Q. Is Sofosbuvir a protease inhibitor?

No. Sofosbuvir is a nucleotide polymerase inhibitor

Q. Does Cimivir 400mg Tablet cure Hepatitis C?

Cimivir 400mg Tablet is used to treat Hepatitis C virus infection. The treatment response with Cimivir 400mg Tablet (in conjunction with other drugs) varies based on baseline host and viral factors.