Manufacturer: Lark Laboratories Ltd
Salt Composition : Fluocinolone acetonide(0.025% w/w), Ciprofloxacin(0.5% w/w), Clotrimazole(1% w/w)
Tube of 20gm Cream
(Inclusive of all taxes)
Ciprolar-FC Cream is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. Wash your hands before and after applying the medicine. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.
Fluocinolone acetonide is a synthetic anti-inflammatory corticosteroid and thus, the effect of its interaction with the body produces vasoconstriction and suppression of membrane permeability, mitotic activity, immune response and release of inflammatory mediators.
Ciprofloxacin is a bactericidal antibiotic of the fluoroquinolone drug class. It inhibits DNA replication by inhibiting bacterial DNA topoisomerase and DNA-gyrase
Clotrimazole exerts its action primarily by damaging the permeability barrier in the fungal cytoplasmic membrane. [6] Clotrimazole thereby inhibits the biosynthesis of ergosterol in a concentration-dependent manner by inhibiting the demethylation of 14 alpha lanosterol
The reported half-life of fluocinolone acetonide ranges between 1.3-1.7 hours. This pharmacokinetic parameter is not relevant as the systemic absorption of fluocinolone acetonide is very minimal and the concentration in urine is lower than the minimum quantitation limit.
Clotrimazole is an imidazole antifungal agent used primarily in the treatment of skin, oral and vaginal candida infections. Clotrimazole is typically given topically or as oral or vaginal troches and has only modest systemic absorption.
The pharmacokinetics of ciprofloxacin in healthy volunteers include a time to peak concentrations after oral dosage (tmax) of 1–1.5 h, oral availability of 0.5–0.7, protein binding of 0.2–0.3, volume of distribution (V) of 2–3 l kg−1, half-life (t1/2) of 3–4 h and fraction excreted unchanged in the urine of 0.4–0.6
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ciprolar-FC
Application site reactions (burning, irritation, itching and redness)
active, untreated tuberculosis.
inactive tuberculosis.
herpes simplex infection of the eye.
a herpes simplex infection.
an infection due to a fungus.
intestinal infection caused by the roundworm Strongyloides.
a condition with low thyroid hormone levels.
diarrhea from an infection with Clostridium difficile bacteria.
diabetes.
low blood sugar.
glucose-6-phosphate dehydrogenase (G6PD) deficiency.
low amount of magnesium in the blood.
low amount of potassium in the blood.
a low seizure threshold.
Onychomycosis. Topical clotrimazole is not effective for onychomycosis.
Pregnancy.
Breast-feeding.
Contraceptive Devices, Menstruation.
Azole Antifungals Hypersensitivity.
Ocular Exposure, Ophthalmic Administration.
Drug-drug Interactions.
Ciprolar-FC Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Ciprolar-FC Cream is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Baby should be closely monitored for development of fever, loss of appetite and diarrhea. In case, any of the above happens please inform your doctor immediately.
Fluocinolone topical is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body and eczema (a skin disease that causes the skin to be dry and itchy and to
Infections of the gastro-intestinal tract and intra-abdominal infections Typhoid fever
Intra-abdominal infections due to Gram-negative bacteria
Infections of the skin and soft tissue
Bone and joint infections
Topical clotrimazole is used to treat tinea corporis (ringworm; fungal skin infection that causes a red scaly rash on different parts of the body), tinea cruris (jock itch; fungal infection of the skin in the groin or buttocks), and tinea pedis (athlete's foot; fungal infection of the skin on the feet and between the
Fluocinolone acetonide is a synthetic anti-inflammatory corticosteroid and thus, the effect of its interaction with the body produces vasoconstriction and suppression of membrane permeability, mitotic activity, immune response and release of inflammatory mediators.
colitis.
CNS disorders.
myasthenia gravis.
peripheral neuropathy.
QT interval prolongation.
tendonitis.
crystalluria.
diabetes.
Clotrimazole topical has no listed serious interactions with any other drugs. Clotrimazole topical has no listed moderate interactions with any other drugs. Clotrimazole topical has no listed minor interactions with any other drugs
Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Store below 30°C
If you miss a dose of Ciprolar-FC Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Ciprolar-FC Cream must be applied as a thin layer on the affected area as prescribed by your doctor.
Do not use this medicine more often or for longer than advised by your doctor.
Before each application, wash the affected area with soap and water and dry well.
Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Q. How long does Ciprolar-FC Cream takes to work?
Usually, Ciprolar-FC Cream starts working soon after applying it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Q. Can I stop applying Ciprolar-FC Cream when I feel better?
No, do not stop applying Ciprolar-FC Cream and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
