Manufacturer: Khandelwal Laboratories Pvt Ltd
Salt Composition : Ciprofloxacin(500mg), Tinidazole(600mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Ciprofloxacin is a bactericidal antibiotic of the fluoroquinolone drug class. It inhibits DNA replication by inhibiting bacterial DNA topoisomerase and DNA-gyrase
Tinidazole is an antiprotozoal, antibacterial agent. The nitro- group of tinidazole is reduced by cell extracts of Trichomonas. The free nitro- radical generated as a result of this reduction may be responsible for the antiprotozoal activity
The pharmacokinetics of ciprofloxacin in healthy volunteers include a time to peak concentrations after oral dosage (tmax) of 1–1.5 h, oral availability of 0.5–0.7, protein binding of 0.2–0.3, volume of distribution (V) of 2–3 l kg−1, half-life (t1/2) of 3–4 h and fraction excreted unchanged in the urine of 0.4–0.6
Tinidazole is excreted by the liver and the kidneys. Tinidazole is excreted in the urine mainly as unchanged drug (approximately 20-25% of the administered dose). Approximately 12% of the drug is excreted in the feces. The elimination half-life is 13.2±1.4 hours and the plasma half-life is 12 to 14 hours
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cipzole TZ
Nausea
Vomiting
Stomach pain
Dryness in mouth
Metallic taste
Headache
diarrhea from an infection with Clostridium difficile bacteria.
diabetes.
low blood sugar.
glucose-6-phosphate dehydrogenase (G6PD) deficiency.
low amount of magnesium in the blood.
low amount of potassium in the blood.
a low seizure threshold.
Contraindicated in patients with a prior history of hypersensitivity to tinidazole or other nitroimidazole derivatives and during the first trimester of pregnancy. Use with caution and reduce dose in severe hepatic Impairment
Cipzole TZ 500 mg/600 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consuming alcohol while taking Cipzole TZ 500 mg/600 mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Cipzole TZ 500 mg/600 mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Baby should be closely monitored for development of fever, loss of appetite and diarrhea. In case, any of the above happens please inform your doctor immediately.
Infections of the upper respiratory tract Acute exacerbation of chronic sinusitis
Chronic suppurative otitis media
Malignant external otitis
Urinary tract infections Uncomplicated cystitis
Tinidazole is indicated for the treatment of bacterial vaginosis (formerly referred to as Haemophilus vaginitis, Gardnerella vaginitis, nonspecific vaginitis, or anaerobic vaginosis) in non-pregnant women
colitis.
CNS disorders.
myasthenia gravis.
peripheral neuropathy.
QT interval prolongation.
tendonitis.
crystalluria.
diabetes.
blood dyscrasias.
neurologic toxicity.
alcoholism.
hemodialysis.
liver disease.
Do not chew, crush or break it. Cipzole TZ 500 mg/600 mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Cipzole TZ 500 mg/600 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Your doctor has prescribed this combination medicine for the treatment of diarrhea and dysentery.
Diarrhea can cause dehydration. Drink plenty of fluids to help rehydrate you.
Consult your doctor if your diarrhea lasts for more than 48 hours.
Do not use Cipzole TZ 500 mg/600 mg Tablet if you have blood in your stool or if you are severely constipated.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Cipzole TZ 500 mg/600 mg Tablet as it may irritate your stomach and also cause excessive drowsiness.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cipzole TZ 500 mg/600 mg Tablet is to be taken with food.
Q. What is Cipzole TZ 500 mg/600 mg Tablet?
Cipzole TZ 500 mg/600 mg Tablet is a combination of two medicines: Tinidazole and Ciprofloxacin. They work by killing the harmful microorganisms that can cause infection. Together they help to treat the infection more effectively.
Q. Is it safe to use Cipzole TZ 500 mg/600 mg Tablet?
Cipzole TZ 500 mg/600 mg Tablet is safe for most of the patients. However, in some patients it may cause common side effects like nausea, vomiting, stomach pain, dizziness, headache, dryness in the mouth, metallic taste, heartburn and other uncommon or rare side effects. If you experience any problem due to the medication, inform your doctor as soon as possible.
Q. What if I don't get better after using Cipzole TZ 500 mg/600 mg Tablet?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Q. Can I stop taking Cipzole TZ 500 mg/600 mg Tablet when I feel better?
No, do not stop taking Cipzole TZ 500 mg/600 mg Tablet and complete the full course of treatment even if you are feeling better. Your symptoms may improve before the infection is completely cured.
Q. What if I miss my dose?
Take Cipzole TZ 500 mg/600 mg Tablet as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.
