Manufacturer: United Biotech Pvt Ltd
Salt Composition : Capecitabine(500mg)
Citabin Tablet should be taken with food within 30 minutes after eating a meal. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Capecitabine is relatively non-cytotoxic in vitro. This drug is enzymatically converted to 5-fluorouracil (5-FU) in vivo. Mechanism of Action: Both normal and tumor cells metabolize 5-FU to 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP).
After oral administration of 1250 mg/m2, capecitabine is rapidly and extensively absorbed from the gastrointestinal tract [with a time to reach peak concentration (tmax) of 2 hours and peak plasma drug concentration (Cmax) of 3 to 4 mg/L] and has a relatively short elimination half-life
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Citabin
Vomiting
Weakness
Nausea
Abdominal pain
Diarrhea
Blisters on fingers/feet
an infection.
very serious loss of body water.
anemia.
decreased blood platelets.
low levels of a type of white blood cell called neutrophils.
coronary artery disease.
abnormal heart rhythm.
abnormal EKG with QT changes from birth.
Citabin Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Citabin Tablet. Please consult your doctor.
Citabin Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Xeloda is indicated as a single agent for adjuvant treatment in patients with Dukes' C colon cancer who have undergone complete resection of the primary tumor when treatment with fluoropyrimidine therapy alone is preferred.
infections.
coronary artery disease.
myelosuppression.
renal dysfunction.
dehydration.
hepatic dysfunction.
Do not chew, crush or break it. Citabin Tablet is to be taken with food.
Store below 30°C
Consult a doctor before taking any medicines.
Citabin Tablet is used alone or in combination with other medicines for the treatment of colon, rectum or breast cancers.
It is oral chemotherapy, hence it is preferred by many patients.
It should be taken within 30 minutes after eating a meal.
The dose and the number of treatment cycles needed will depend on the type and stage of cancer that is being treated.
It may cause dizziness and tiredness. Don't drive or do anything requiring concentration until you know how it affects you.
Frequency of hair loss is much less compared to other chemotherapy drugs.
Do not take it if you are pregnant or breastfeeding.
Your doctor may regularly monitor your blood cells during treatment with this medicine. Inform your doctor immediately if you notice signs of infection such as fever, sore throat, rash or severe diarrhea.
Inform your doctor immediately if you start to have side effects such as diarrhea, vomiting, nausea, mouth sores, chest pain or loss of appetite.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Citabin Tablet is to be taken with food.
Q. What are the side effects of Citabin Tablet?
The side effects of Citabin Tablet include stomach pain or upset stomach, constipation, loss of appetite, and change in ability to taste food. It may also cause increased thirst, unusual tiredness or weakness, dizziness, headache, hair loss, skin rash, back, join, or muscle pain. You may also experience red, swollen, itchy, or teary eyes and trouble falling asleep or staying asleep. Inform your doctor if any of these symptoms are severe and persist for long.
Q. What are the serious side effects of Citabin Tablet?
The use of Citabin Tablet may cause various serious side effects such as diarrhea, nausea, vomiting, sores in the mouth, swelling, pain, redness, or peeling of skin on the palms and soles of the feet. One may also experience fever, chills, sore throat, or other signs of an infection, swelling of the hands, feet, ankles, or lower legs, chest pain or pressure, fast heartbeat, dark urine and yellowing of the skin or eyes. Inform your doctor immediately if you experience any such symptoms.
Q. Does Citabin Tablet make you tired?
Yes, Citabin Tablet may make you tired and you may also feel weak, as these are the most common side effects of the medicine. Hence, it is possible that use of Citabin Tablet may affect your ability to drive or operate machinery.
Q. What is the most important information that I should know about Citabin Tablet?
It is important to know that Citabin Tablet can interfere with working of blood thinners like warfarin. This type of interference can cause a change in the rate of clot formation and can cause bleeding that can even lead to death. The risk is higher for cancer patients, especially those who are over 60 years of age. Seek immediate medical help if you experience symptoms like unusual bleeding, vomiting or spitting up blood or brown material that resembles coffee grounds, bloody or black, tarry stools, blood in urine, red or dark-brown urine, or easy bruising.
Q. How long do I need to take Citabin Tablet?
The duration of treatment with Citabin Tablet depends on the nature of your illness and individual response to treatment. Usually, it is given as a series of treatment cycles, each of these cycles lasts for 21 days. Citabin Tablet is given for 14 days followed by a rest period of 7 days. You should continue taking this medicine for the time prescribed by the doctor.
Q. Do I need to use birth control method while using Citabin Tablet?
Yes, birth control methods are a must while using Citabin Tablet, as this medicine may harm your unborn child. Females should continue using these methods for 6 months after the final dose. On the other hand, men using these medicines whose partners can become pregnant should use effective birth control during treatment and for 3 months after the final dose.
Q. What kind of drug is Citabin Tablet?
Citabin Tablet is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. Citabin Tablet is classified as an "antimetabolite." Citabin Tablet itself is not a cytostatic medicine; it gets converted into an active anti-cancer medicine (more in tumour tissue than in normal tissue) only after getting absorbed by the body.
Q. Do I need to get any tests done while on Citabin Tablet?
The doctor will check you on a regular basis while you are taking Citabin Tablet to monitor side effects and your response to therapy. You may need to get your blood test done as advised by the doctor to monitor your complete blood count (CBC) as well as the function of kidneys and liver.
Q. Should Citabin Tablet be taken with or without food?
Capecitabine should be taken within 30 minutes after finishing a meal. Swallow tablets as a whole (do not cut or crush) with water. Consult your doctor if you cannot take the whole tablet. If Citabin Tablet needs to be crushed or cut, it should be done by a trained professional using appropriate equipment and safety procedures.
