Citabol 200mg (Injection)

Manufacturer: Venus Remedies Ltd

Salt Composition : Gemcitabine(200mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Citabol 200mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.



Basic Information

Mechanism Of Action

The most important mechanism of action of gemcitabine is inhibition of DNA synthesis (Huang et al., 1991). When dFdCTP is incorporated into DNA, a single deoxynucleotide is incorporated afterwards, preventing chain elongation 

Pharmacokinets

Gemcitabine plasma concentrations generally reach a plateau after 15–30 min during the standard 30 min infusion protocol. Linear pharmacokinetics have been described over the range 40–3650 mg/m2, and nonlinear pharmacokinetics at higher doses 

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Citabol

Nausea

Vomiting

Loss of appetite

Hair loss

Low blood platelets

Allergic reaction

Breathlessness

Decreased white blood cell count

Increased liver enzymes

Anemia (low number of red blood cells)

Flu-like symptoms

Blood in urine

Skin rash

Protein in urine


Contra Indications

an infection.

hemolytic uremic syndrome, a condition that affects the kidney and the blood.

decreased function of bone marrow.

anemia.

decreased blood platelets.

low levels of a type of white blood cell called neutrophils.

Pregnancy Related Information

Citabol 200mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

Citabol 200mg Injection may cause excessive drowsiness with alcohol.


Breast Feeding Related Information

Citabol 200mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Gemcitabine is indicated as first-line treatment for patients with locally advanced (nonresectable Stage II or Stage III) or metastatic (Stage IV) adenocarcinoma of the pancreas. Gemcitabine is indicated for patients previously treated with fluorouracil

Interactions

infections.

cardiovascular dysfunction.

hemolytic uremic syndrome.

myelosuppression.

cerebrovascular disease.

edema.

hepatic dysfunction.

paresthesia.


Typical Dosage

Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Overdose

Consult a doctor before taking any medicines

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.