Manufacturer: Zydus Cadila
Salt Composition : Citicoline(500mg), Piracetam(800mg)
Citico Plus 500 mg/800 mg Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.
Citicoline enhances cellular communication by increasing the availability of neurotransmitters, including acetylcholine, norepinephrine, and dopamine. In simple terms, the choline component of citicoline is used to create acetylcholine, which is a primary executive neurotransmitter in the human brain
Piracetam improves the function of the neurotransmitter acetylcholine via muscarinic cholinergic (ACh) receptors, which are implicated in memory processes. Furthermore, piracetam may have an effect on NMDA glutamate receptors, which are involved with learning and memory processes.
Citicoline is water-soluble, with more than 90% oral bioavailability. Plasma levels peak one hour after oral ingestion, and a majority of the citicoline is excreted as CO 2 in respiration, and again 24 hours after ingestion, where the remaining citicoline is excreted through urine
Piracetam is predominantly excreted via renal elimination, where about 80-100% of the total dose is recovered in the urine. Approximately 90% of the dose of piracetam is excreted in the urine as unchanged drug 4. The plasma half life of piracetam is approximately 5 hours following oral or intravenous administration
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Citico Plus
Weight gain
Hyperactivity
Stomach pain
Nervousness
Diarrhea
Decreased blood pressure
you are allergic to Citicoline or any components of this medicine.
Conditions causing increased muscle tone or stiffness (rigidity, spasticity, or dystonia)
Piracetam is contra-indicated in patients with severe renal impairment (renal creatinine clearance of less than 20 ml per minute). It is also contraindicated in patients with cerebral haemorrhage and in patients suffering from Huntington's Chorea.
Information regarding the use of Citico Plus 500 mg/800 mg Tablet during pregnancy is not available. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Citico Plus 500 mg/800 mg Tablet. Please consult your doctor.
Information regarding the use of Citico Plus 500 mg/800 mg Tablet during breastfeeding is not available. Please consult your doctor.
Citicoline was (2011) the 10th drug by rank of billed amount. Its approved indications are stroke (acute and sub-acute) and head injury, but not cognitive decline associated with age, the presumed indication for most of its use.
Piracetam is most commonly used for breath-holding attacks, seizure disorder (epilepsy), dizziness (vertigo), a learning disorder marked by difficulty reading (dyslexia), and a movement disorder often caused by antipsychotic drugs (tardive dyskinesia).
CITICOLINE alter the effect of antiparkinsonian drugs (levodopa, carbidopa, and entacapone) when given with it. The effectiveness of CITICOLINE is altered when given with another nootropic (meclofenoxate). Drug-food interactions: No interactions found.
cilostazol.
clopidogrel.
dipyridamole.
eptifibatide.
prasugrel.
ticlopidine.
tirofiban.
Do not chew, crush or break it. Citico Plus 500 mg/800 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Citico Plus 500 mg/800 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Citico Plus 500 mg/800 mg Tablet may cause drowsiness and shakiness which may affect your concentration and driving ability so do not drive unless you are feeling well.
Dose adjustment may be needed in patients with kidney disease. Please consult your doctor.
Citico Plus 500 mg/800 mg Tablet can cause weight gain, maintain good eating habits and exercise regularly to prevent this.
Side effects such as trouble sleeping, diarrhoea, stomach pain, decreased blood pressure, irregular heart rate may occur, which is not with everyone. Inform your doctor if you notice any other side effect.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Citico Plus 500 mg/800 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. How to manage weight gain associated with the use of Citico Plus 500 mg/800 mg Tablet?
There are reports which suggest that the use of Citico Plus 500 mg/800 mg Tablet can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain rather than losing increased weight.
Q. What are the instructions for storage and disposal of Citico Plus 500 mg/800 mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
