Manufacturer: Jagsonpal Pharmaceuticals Ltd
Salt Composition : Cefpodoxime Proxetil(200mg), Clavulanic Acid(125mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Cladoxim 200 mg/125 mg Tablet is a prescription medicine. It is advised to take it as per the prescription. It can be taken with or without food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.
Cefpodoxime controls the growth of bacteria and kills them by inhibiting the synthesis of the bacterial cell wall. However, the bacteria make an enzyme (beta-lactamases) that can destroy Cefpodoxime
Over the recommended dosing range, the Tmax was approximately 2 to 3 hours and the T1/2 ranged from 2.09 to 2.84 hours. Mean Cmax was 1.4 mcg/mL for the 100 mg dose, 2.3 mcg/mL for the 200 mg dose, and 3.9 mcg/mL for the 400 mg dose.
Clavulanic acid along with amoxicillin is well absorbed from stomach after oral administration without having any impact of fasting and fed state on the pharmacokinetics of amoxicillin. While relative bioavailability of clavulanic acid becomes reduced when administered after 30 and 150 min of high fat breakfast.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cladoxim
Nausea
Diarrhea
Stomach pain
Headache
If you are allergic to cefpodoxime proxetil, clavulanic acid or similar medicines like cephalosporin class of antibiotics. If you have problems with your liver or kidney. If you have an infection that is caused by the bacteria Clostridium difficile.
Cladoxim 200 mg/125 mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is not known whether it is safe to consume alcohol with Cladoxim 200 mg/125 mg Tablet. Please consult your doctor.
Cladoxim 200 mg/125 mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Cefpodoxime proxetil+Clavulanic acid is used for the treatment of bacterial infections of the skin, ear, respiratory tract, urinary tract, lungs, throat and tonsil and sexually transmitted diseases
CEFPODOXIME PROXETIL+CLAVULANIC ACID may have interaction with anticoagulants (e.g. warfarin), anti-gout (e.g. probenecid), diuretics (e.g. furosemide), and vitamin supplements (e.g. calcium, vitamin D). Drug-Food Interactions: No interactions found/established.
Do not chew, crush or break it. Cladoxim 200 mg/125 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Cladoxim 200 mg/125 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Take it with food and plenty of fluids to avoid an upset stomach.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Cladoxim 200 mg/125 mg Tablet may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking Cladoxim 200 mg/125 mg Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cladoxim 200 mg/125 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can the use of Cladoxim 200 mg/125 mg Tablet cause diarrhea?
Yes, the use of Cladoxim 200 mg/125 mg Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.
Q. How long does Cladoxim 200 mg/125 mg Tablet takes to work?
Usually, Cladoxim 200 mg/125 mg Tablet starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Q. What if I don't get better after using Cladoxim 200 mg/125 mg Tablet?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Q. Can I stop taking Cladoxim 200 mg/125 mg Tablet when I feel better?
No, do not stop taking Cladoxim 200 mg/125 mg Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
Q. What is Cladoxim 200 mg/125 mg Tablet?
Cladoxim 200 mg/125 mg Tablet is a combination of two medicines: Cefpodoxime and Clavulanic acid. This medication is used to treat bacterial infection. This medication works by killing the harmful bacteria that cause infection.
Q. Can the use of Cladoxim 200 mg/125 mg Tablet cause any serious side effects?
Cladoxim 200 mg/125 mg Tablet may cause serious side effects in very few patients (less than 1 in 1,000). Inform the doctor straight away if you get bloody diarrhea, yellowing of the eyes and skin, bruising or skin discoloration, shortness of breath, widespread rash, skin peeling and fever. All of these reactions needs urgent medical attention.
Q. Can I stop taking Cladoxim 200 mg/125 mg Tablet when my symptoms are relieved?
No, do not stop taking Cladoxim 200 mg/125 mg Tablet and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.
Q. Can Cladoxim 200 mg/125 mg Tablet cause allergic reaction?
Yes, Cladoxim 200 mg/125 mg Tablet can cause allergic reaction and is considered to be harmful patients with known allergy to a group of antibiotics called Cephalosporins. Get emergency medical help if you notice any of the signs of an allergic reaction: hives; difficulty in breathing; swelling of your face, lips, tongue or throat.
Q. Are there any specific contraindications associated with the use of Cladoxim 200 mg/125 mg Tablet?
The use of Cladoxim 200 mg/125 mg Tablet is considered to be harmful for patients with known allergy to penicillins or any other excipients present in this medicine. This medicine should not be used in patients with previous history of liver damage associated with Cladoxim 200 mg/125 mg Tablet.
Q. Can I take oral contraceptive pills while taking Cladoxim 200 mg/125 mg Tablet?
No, Cladoxim 200 mg/125 mg Tablet can make birth control pills less effective. So, ask your doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm and spermicide).
Q. Can I take a higher than the recommended dose of this medicine?
No, taking a higher than the recommended dose of Cladoxim 200 mg/125 mg Tablet can increase the risks of side effects. Cladoxim 200 mg/125 mg Tablet takes time to show its full effect and treat your infection. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.
Q. What is the recommended storage condition for Cladoxim 200 mg/125 mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
