Manufacturer: Alkem Laboratories Ltd
Salt Composition : Amoxycillin(1000mg), Clavulanic Acid(62.5mg)
Clavam-XR Tablet is best taken with a meal to reduce the chance of a stomach upset. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose will depend on what you are being treated for, but you should always complete a full course of this antibiotic as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive and the infection may come back or worsen.
Amoxicillin is similar to penicillin in its bactericidal action against susceptible bacteria during the stage of active multiplication. It acts through the inhibition of cell wall biosynthesis that leads to the death of the bacteria.
It works by stopping the growth of bacteria. Clavulanic acid is in a class of medications called beta-lactamase inhibitors. It works by preventing bacteria from destroying amoxicillin. Antibiotics will not work for colds, flu, or other viral infections.
The half-life of amoxicillin is 61.3 minutes. Approximately 60% of an orally administered dose of amoxicillin is excreted in the urine within 6 to 8 hours. Detectable serum levels are observed up to 8 hours after an orally administered dose of amoxicillin.
Clavulanic acid along with amoxicillin is well absorbed from stomach after oral administration without having any impact of fasting and fed state on the pharmacokinetics of amoxicillin. While relative bioavailability of clavulanic acid becomes reduced when administered after 30 and 150 min of high fat breakfast.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clavam
Vomiting
Nausea
Diarrhea
diarrhea from an infection with Clostridium difficile bacteria.
mononucleosis, the kissing disease.
liver problems.
blockage of normal bile flow.
severe renal impairment.
Clavam-XR Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol with Clavam-XR Tablet does not cause any harmful side effects.
Clavam-XR Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Amoxicillin alone is indicated to treat susceptible bacterial infections of the ear, nose, throat, genitourinary tract, skin, skin structure, and lower respiratory tract.
Clavulanic acid combined with other antibiotics is indicated to prevent the development of drug-resistant strains of bacteria and promotes their therapeutic antibacterial effects.
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clavam-XR Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Clavam-XR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Clavam-XR Tablet may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Take it with food and plenty of fluids to avoid an upset stomach.
Stop taking Clavam-XR Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Do not use leftover medicine for treating any infection in the future. Always consult your doctor before taking any antibiotic.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clavam-XR Tablet is to be taken with food.
Q. What is Clavam-XR Tablet?
Clavam-XR Tablet is a combination of two medicines: Amoxycillin and Clavulanic acid. It is used to treat bacterial infections like, tonsillitis, sinusitis, otitis media, respiratory tract infections, urinary tract infections, boils, abscesses, cellulitis, wound infection, bone infection, and oral cavity infections. The medicine works by killing the harmful bacteria that cause infections.
Q. Is it safe to use Clavam-XR Tablet?
Clavam-XR Tablet is safe to use when taken as advised by the doctor. However, in some patients, it may cause common side effects like diarrhea, nausea, vomiting, rash, allergic reaction and other uncommon or rare side effects. If you experience any persistent problem during the course of your treatment, inform your doctor as soon as possible.
Q. Are there any specific cautions associated with the use of Clavam-XR Tablet?
The use of Clavam-XR Tablet is considered to be harmful for patients with known allergy to penicillins or any other ingredient of the medicine. It should not be used in patients with a history of liver disease. Therefore, inform your doctor if you are allergic to any medicines.
Q. Can the use of Clavam-XR Tablet cause contraceptive failure?
Yes, the use of Clavam-XR Tablet can lower the efficacy of birth control pills. Consult your doctor and seek advice regarding the use of other methods of contraception (e.g., condom, diaphragm, spermicide) while you are taking Clavam-XR Tablet.
Q. Can I take a higher than the recommended dose of Clavam-XR Tablet?
No, taking a higher than the recommended dose of Clavam-XR Tablet can increase the risks of side effects. Clavam-XR Tablet takes time to show its full effect and treat your infection. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.
Q. What are the instructions for the storage and disposal of Clavam-XR Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose off the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can I stop taking Clavam-XR Tablet when my symptoms are relieved?
No, do not stop taking Clavam-XR Tablet before completing the full course of the treatment, even if you feel better. Your symptoms may improve before the infection is completely cured. Hence, continue taking the medicine for the due course as the medicine may still be showing beneficial effects.
