Manufacturer: Dr Reddy's Laboratories Ltd
Salt Composition : Hydroquinone(2% w/w), Tretinoin(0.025% w/w), Fluocinolone acetonide(0.01% w/w)
Tube of 15gm Cream
(Inclusive of all taxes)
Clearz Max Cream should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. It is for external use only.
Fluocinolone is a steroid, which works by blocking the production of certain chemical substances in the body (prostaglandins) which cause itching, swelling and redness
Hydroquinone is absorbed through the skin and metabolized primarily to sulfate and glucuronide conjugates, which are excreted in the urine. Additional metabolites include benzoquinone, multiple glutathione conjugates, and N-acetyl cysteine conjugates.
The principal mechanisms proposed to explain the increased disappearance of tretinoin from plasma include: (i) decreased intestinal absorption; (ii) enhanced enzymatic catabolism; and (iii) the induction of cytoplasmic retinoic acid binding proteins (CRABP), which leads to increased drug sequestration.
The reported half-life of fluocinolone acetonide ranges between 1.3-1.7 hours. This pharmacokinetic parameter is not relevant as the systemic absorption of fluocinolone acetonide is very minimal and the concentration in urine is lower than the minimum quantitation limit.
Erythema (skin redness)
Skin peeling
Burning sensation
Dryness
Itching
Allergic reaction or hypersensitivity hydroquinone.
Sun exposure.
The use of this drug requires caution with other medications that cause photosensitivity.
Hypersensitivity to the drug, drug class, or drug formulation components.
Caution if hypersensitivity to fish products (0.05% gel, 0.05% lotion forms)
Caution if sunburn.
Caution if photosensitivity.
Caution if eczema.
Caution if pregnancy 1st trimester.
active, untreated tuberculosis.
inactive tuberculosis.
herpes simplex infection of the eye.
a herpes simplex infection.
an infection due to a fungus.
intestinal infection caused by the roundworm Strongyloides.
a condition with low thyroid hormone levels.
diabetes.
Clearz Max Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Clearz Max Cream is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
HYDROQUINONE USP, 4% SKIN BLEACHING CREAM is indicated for the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation
Topical application for treatment of acne vulgaris
Adjunctive palliative treatment of photoaging: Fine facial wrinkles Facial skin roughness
Facial mottled hyperpigmentation
Fluocinolone topical is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body and eczema (a skin disease that causes the skin to be dry and itchy
Clearz Max Cream is applied externally on the skin, thus it is less likely to interact with other medicines taken orally. However, it may interact with other topically applied creams, lotion and gel. You should always consult your doctor if you are taking other medicines (another topical gel or cream) for treating other health conditions.
Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Store below 30°C
If you miss a dose of Clearz Max Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed Clearz Max Cream to reduce skin pigmentation.
Along with applying Clearz Max Cream, wear long-sleeved clothing, sunglasses, hat whenever you step outside in the hot sun for better protection.
Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor.
Use moisturizer regularly to overcome skin dryness during the course of treatment.
You may also use certain safe cosmetics (after consulting with your doctor) in order to lighten pigmentation.
Before using Clearz Max Cream, inform your doctor if you have any skin problems or are applying any other medicines to your skin.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
