Manufacturer: Nirlife Healthcare
Salt Composition : Clindamycin, Nicotinamide
Tube of 20gm Cream
(Inclusive of all taxes)
Clindanir Cream is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. Wash your hands before and after applying the medicine. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.
The basis for these investigations is the variety of potential mechanisms of action of nicotinamide and zinc, including an anti-inflammatory effect via inhibition of leukocyte chemotaxis, lysosomal enzyme release, lymphocytic transformation, mast cell degranulation, bacteriostatic effect against Propionibacterium acnes
Clindamycin works primarily by binding to the 50s ribosomal subunit of bacteria. This agent disrupts protein synthesis by interfering with the transpeptidation reaction, which thereby inhibits early chain elongation
The pharmacokinetics of nicotinamide were studied in four human volunteers after oral doses of 1–6 g. Plasma concentrations and clearance rates of the vitamin were found to be dose-dependent, with a half-life of ∼7–9 h for the two highest doses administered (4 and 6 g), ∼4 h with 2 g and ∼1.5 h with a 1-g dose
Clindamycin is absorbed well orally and can be given parenterally. Clindamycin diffuses well into body fluids except cerebrospinal fluid; it is concentrated in phagocytes. Most of the drug is metabolized; metabolites are excreted in bile and urine
Skin peeling
Dry skin
Erythema (skin redness)
Burning sensation at the site of application
diarrhea from an infection with Clostridium difficile bacteria.
myasthenia gravis, a skeletal muscle disorder.
Crohn's disease.
ulcerative colitis, an inflammatory condition of the intestines.
severe liver disease.
blood in the bowel movement.
severe renal impairment.
a type of joint disorder due to excess uric acid in the blood called gout. increased risk of bleeding due to clotting disorder. a sudden worsening of heart related chest pain called angina. low blood pressure
Information regarding the use of Clindanir Cream during pregnancy is not available. Please consult your doctor.
No interaction found/established
Clindanir Cream is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Clindamycin is indicated for the treatment of pelvic infections including pelvic inflammatory disease, pelvic abscesses, endometritis and bacterial vaginosis
Vitamin B3 is essential for good health; deficiency leads to a serious illness, pellagra. Oral nicotinamide can be used effectively to treat pellagra. Nicotinamide used as medicine may benefit the skin in several different ways.
Niacinamide might slow blood clotting. Taking niacinamide along with medications that also slow blood clotting might increase the risk of bruising and bleeding. Primidone is broken down by the body. Niacinamide might decrease how fast the body breaks down primidone
Cisatracurium The risk or severity of neuromuscular blockade can be increased when Clindamycin is combined with Cisatracurium.
Clarithromycin The metabolism of Clindamycin can be decreased when combined with Clarithromycin.
Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Store below 30°C
If you miss a dose of Clindanir Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose
Consult a doctor before taking any medicines.
Clindanir Cream may take several weeks to show its action. Keep using it as suggested by your doctor.
Wash your skin with a mild cleanser and pat it dry before applying Clindanir Cream.
Apply it as a thin layer onto clean, dry, unbroken skin affected by acne.
It may cause minor burning, stinging or irritation when applied. Inform your doctor if this does not go away.
Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the cream in these areas.
It makes your skin more sensitive toward sunlight. Wear protective clothing or use sunscreen while stepping out.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Q. Will Clindanir Cream be more effective if I overuse it?
No, do not overuse Clindanir Cream. It can cause over-absorption of the medicine into the body and cause severe diarrhea. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.
Q. What are the recommended instructions for the storage and disposal of Clindanir Cream?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can I use Clindanir Cream as a spot treatment (for single pimple)?
It is not a spot treatment and should not be used to treat a single pimple. Clindanir Cream should be applied to the entire face. Using it once everyday can help treat your acne.
Q. How long does Clindanir Cream take to work?
It may take up to 2-3 weeks before your symptoms improve. Clindanir Cream may take some time to deliver significant results. Use the medicine as directed and let your doctor know if your symptoms do not improve or get worse.
