Manufacturer: Alembic Pharmaceuticals Ltd
Salt Composition : Clarithromycin(500mg)
Cloff 500 Tablet is also effective against some infections (e.g., MAC or Mycobacterium avium complex) seen in people with reduced immunity. It stops the bacteria from growing, which helps to resolve your symptoms and cure your infection. This medicine is taken orally, preferably either one hour before or 2 hours after a meal. No antacids should be taken within 2 hours of taking this medicine. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.
Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process.
Clarithromycin is primarily metabolised by cytochrome P450 (CYP) 3A isozymes and has an active metabolite, 14-hydroxyclarithromycin. The reported mean values of total body clearance and renal clearance in adults have ranged from 29.2 to 58.1 L/h and 6.7 to 12.8 L/h, respectively.
Abdominal pain
Diarrhea
Headache
Nausea
Taste change
Vomiting
Indigestion
Rash
diarrhea from an infection with Clostridium difficile bacteria.
low amount of magnesium in the blood.
low amount of potassium in the blood.
myasthenia gravis, a skeletal muscle disorder.
coronary artery disease.
rapid ventricular heartbeat
Cloff 500 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consuming alcohol with Cloff 500 Tablet does not cause any harmful side effects.
Cloff 500 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Mild to moderate susceptible pharyngitis/tonsillitis, acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, acute maxillary sinusitis, acute otitis media, uncomplicated skin and skin structure infections
Alfuzosin.
Astemizole.
Bepridil.
Cisapride.
Colchicine.
Dihydroergotamine.
Eletriptan.
Eliglustat
Do not chew, crush or break it. Cloff 500 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Avoid Cloff 500 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Store below 30°C
If you miss a dose of Cloff 500 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Your doctor has prescribed Cloff 500 Tablet to cure your infection and improve your symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
Take it 1 hour before or two hours after food.
Do not take antacids 2 hours before or after taking Cloff 500 Tablet.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Stop taking Cloff 500 Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cloff 500 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Avoid Cloff 500 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Q. Can the use of Cloff 500 Tablet cause diarrhea?
Yes, the use of Cloff 500 Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.
Q. How long does Cloff 500 Tablet takes to work?
Usually, Cloff 500 Tablet starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Q. What if I don't get better after using Cloff 500 Tablet?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Q. Can the use of Cloff 500 Tablet cause infertility?
There is no firm evidence to suggest that the use of Cloff 500 Tablet will cause infertility in males or females.
