Clomeva NC 50mg Tablet (10'S)


Clomeva NC 50mg Tablet should be taken with or without food, preferably at a fixed time each day. It should be taken as advised by the doctor. The dose and how often you take it depends on what you are taking it for. The medicine is not recommended for a longer period. 



Basic Information

Mechanism Of Action

Clomeva NC 50mg Tablet is a combination of three medicines: Clomiphene, Coenzyme Q10 and Acetylcysteine which treat female infertility. Clomiphene is a partial estrogen agonist which works by stimulating the release of eggs from the ovary

Pharmacokinets

Most clomifene metabolism occurs in the liver, where it undergoes enterohepatic recirculation. Clomifene and its metabolites are excreted primarily through feces (42%), and excretion can occur up to 6 weeks after discontinuation.

Plasma concentrations of coenzyme Q10 were measured by HPLC with electrochemical detection over 48 hours. Solubilized coenzyme Q10 exhibited high absorption creating higher plasma concentrations of the drug, as a result of which its bioavailability constituted 264% of that for the powder

After an oral dose of N-acetylcysteine 200 to 400 mg the peak plasma concentration of 0.35 to 4 mg/L is achieved within 1 to 2 hours. Although the data are conflicting, it appears that the administration of charcoal may interfere with drug absorption, with up to 96% of the drug adsorbed on to the charcoal

Side Effects

Vomiting

Headache

Nausea

Irritation

Hot flashes

Metrorrhagia (menstrual bleeding at irregular intervals)

Ovarian hyperstimulation syndrome

Breast discomfort


Contra Indications

Abnormal uterine bleeding

Allergic reactions to this product

Anaphylactoid reactions to Acetylcysteine

History of liver dysfunction

Hypersensitivity to this drug

Liver disease

Ovarian cysts

Pituitary tumor

Pregnancy

Uncontrolled thyroid or adrenal dysfunction

Pregnancy Related Information

Clomeva NC 50mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.


Product And Alcohol Interaction

Caution is advised when consuming alcohol with Clomeva NC 50mg Tablet. Please consult your doctor.


Breast Feeding Related Information

Clomeva NC 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

Clomeva NC 50mg Tablet helps in the production and development of healthy eggs in women. This improves fertility in women and increases the chance of a successful pregnancy. It is commonly used in women with polycystic ovary syndrome (PCOS) who experience infertility

Interactions

Antihypertensive drugs

Aspirin

Clopidogrel

Insulin

Kanamycin

None reported

Photofrin

Warfarin

Typical Dosage

Do not chew, crush or break it. Clomeva NC 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Clomeva NC 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

Clomeva NC 50mg Tablet is prescribed to women who cannot get pregnant because they are not ovulating or have a condition called polycystic ovary syndrome.

Take Clomeva NC 50mg Tablet exactly as prescribed by doctor. Timing of the doses is very important for its success.

It should not be used for very long. Talk to your doctor if you have used this medicine 3 times with no success.

It may cause problems with your eyesight. Be cautious before driving or using machines.


How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clomeva NC 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.


FAQs

Q. How and in what dose should I take Clomeva NC 50mg Tablet?

For best results, take Clomeva NC 50mg Tablet strictly as per the advice of your doctor. The number of doses you take each day, and the duration for which you take the medicine depends on the medical problem being treated.

Q. After how many days of Clomeva NC 50mg Tablet intake should I have sex to get pregnant?

It is ideal to have sex after 5-10 days of taking Clomeva NC 50mg Tablet. However, your doctor may examine you regularly during the treatment and suggest you the best possible days.

Q. For how many cycles can I take Clomeva NC 50mg Tablet?

Your treatment with Clomeva NC 50mg Tablet may be repeated by the doctor until you get pregnant. However, the treatment can be repeated only for up to 4 menstrual cycles.

Q. What are the common side effects of using Clomeva NC 50mg Tablet?

The most common side effects associated with Clomeva NC 50mg Tablet are hot flushes (red and warm face), stomach discomfort, and breast pain. Most of these symptoms are temporary. However, if they persist, check with your doctor as soon as possible.