Manufacturer: Ipca Laboratories Ltd
Salt Composition : Clopidogrel(75mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Clopact A 75 mg/75 mg Tablet should be taken with food regularly at a fixed time each day. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. Lifestyle changes like low-fat diet, exercise and not smoking may help this medicine to work better.
The active metabolite of clopidogrel selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet P2Y12 receptor and the subsequent ADP- mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation. This action is irreversible
In the liver, approximately 15% of absorbed clopidogrel is metabolized by the cytochrome P450 (CYP) system to generate its active metabolite via a 2-step bioactivation process, whereas the rest 85% is hydrolyzed by carboxylesterase 1 (CES1) to an inactive carboxylic acid derivative.
Abdominal pain
Bruise
Diarrhea
Gastrointestinal bleeding
Increased bleeding tendency
Nosebleeds
General Information. ...
Bleeding, GI bleeding, intracranial bleeding, peptic ulcer disease, surgery, trauma. ...
Hepatic disease. ...
Renal disease, renal failure, renal impairment. ...
Poor metabolizers. ...
Epidural anesthesia, labor, obstetric delivery, pregnancy, spinal anesthesia. ...
Breast-feeding. ...
Geriatric.
Clopact A 75 mg/75 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Clopact A 75 mg/75 mg Tablet.
Clopact A 75 mg/75 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use during a percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) and stable ischemic heart disease. ...
Primary prevention of thromboembolism atrial fibrillation.
Symptomatic carotid artery stenosis.
Secondary prevention post-coronary artery bypass grafting.
Diabetes drug. In most cases, repaglinide should not be taken with clopidogrel. ...
Stomach acid drugs (proton pump inhibitors) ...
Nonsteroidal anti-inflammatory drugs (NSAIDs) ...
Blood thinners.
Drugs used to treat depression. ...
Salicylates (aspirin) ...
Opioids.
Do not chew, crush or break it. Clopact A 75 mg/75 mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Clopact A 75 mg/75 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Clopact A 75 mg/75 mg Tablet to lower your risk of heart attack and stroke.
Take it with food to avoid an upset stomach.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.
Let your doctor know you are taking Clopact A 75 mg/75 mg Tablet before undergoing any surgical procedure.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clopact A 75 mg/75 mg Tablet is to be taken with food.
Q. Why have I been prescribed Clopact A 75 mg/75 mg Tablet?
You may have been prescribed Clopact A 75 mg/75 mg Tablet if you had a heart attack, were treated with stents in your coronary arteries, or had coronary artery bypass graft surgery (CABG).
Q. Is Clopact A 75 mg/75 mg Tablet a blood thinner?
Yes, Clopact A 75 mg/75 mg Tablet is a type of blood thinner. It works by preventing platelets (type of blood cells) from sticking together and forming clots. This action of Clopact A 75 mg/75 mg Tablet helps in preventing conditions like heart attack or stroke in people with heart disease, who have recently suffered a heart attack or severe heart-related chest pain (unstable angina).
Q. How long do I need to take Clopact A 75 mg/75 mg Tablet after stent insertion?
Your doctor will suggest the exact duration for which you may have to take Clopact A 75 mg/75 mg Tablet. The duration will be decided after considering various factors like the illness you are being treated for, type of stent inserted, any episodes of bleeding experienced by you during treatment, etc. Usually, Clopact A 75 mg/75 mg Tablet is prescribed for a minimum duration of 1 year. However, it is advised to follow your doctor's advice precisely to get maximum benefit of Clopact A 75 mg/75 mg Tablet. Do not stop the medication on your own, consult your doctor first. Sudden discontinuation may increase the chances of clot formation in the stent, heart attack and can even lead to death.
Q. Can I drink alcohol while taking Clopact A 75 mg/75 mg Tablet?
It is not advised to take alcohol while taking Clopact A 75 mg/75 mg Tablet, as alcohol may increase your chance of stomach bleeding. As a result, you may vomit blood (which may be bright red blood or black/dark brown like coffee grounds) or you may have bloody or black tarry stools. Discuss with your doctor if you are not sure.
Q. What is the most important information I need to know about Clopact A 75 mg/75 mg Tablet?
Clopact A 75 mg/75 mg Tablet may cause serious or life-threatening bleeding. Moreover, you may bruise easily and it may take longer than usual for bleeding to stop even if you have a minor injury like a small cut while shaving. Get emergency medical help if you notice excessive or prolonged bleeding. You should inform your doctor if you notice black tarry stools or if there is blood in the urine. Be vigilant on any signs of stroke such as sudden numbness or weakness (one side or both sides of the body), difficulty walking, mental confusion, slurred speech, dizziness and any unexplained headache. Contact your doctor immediately if you develop any such signs of stroke as stroke is an uncommon side effect of Clopact A 75 mg/75 mg Tablet and needs urgent medical attention as it can otherwise be fatal.
Q. Do I need to stop Clopact A 75 mg/75 mg Tablet before surgery?
Your doctor will decide whether you need to stop taking Clopact A 75 mg/75 mg Tablet before any surgery or treatment or not. Usually, if a surgery or treatment is planned beforehand, the doctor may stop Clopact A 75 mg/75 mg Tablet a few days (usually 7 days) before the surgery or treatment owing to the increased risk of bleeding during the procedure. You should not stop taking Clopact A 75 mg/75 mg Tablet on your own without discussing it with your doctor.
Q. Who should not take Clopact A 75 mg/75 mg Tablet?
Clopact A 75 mg/75 mg Tablet is not recommended for people who are allergic to it or any of its ingredients. Do not take Clopact A 75 mg/75 mg Tablet if you have or ever had severe liver disease, stomach ulcers, bleeding in the brain (stroke or a transient ischemic attack, also known as TIA), or if you have a bleeding disorder known as hemophilia (disease in which blood does not clot normally). Additionally, avoid taking Clopact A 75 mg/75 mg Tablet if you are trying to get pregnant, already pregnant, or breastfeeding.
Q. What if I forget to take a dose of Clopact A 75 mg/75 mg Tablet?
If you forget to take a dose of Clopact A 75 mg/75 mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Q. What should I avoid while taking Clopact A 75 mg/75 mg Tablet?
Avoid activities that may increase your chances of bleeding. Be extra careful while shaving or brushing your teeth to prevent bleeding. Also, you should avoid taking painkillers, but if you need to take one like ibuprofen for joint pain, headache, backache, etc. then consult your doctor first. This is because taking pain killers with Clopact A 75 mg/75 mg Tablet may increase your chances of developing a stomach ulcer and bleeding. Refrain from taking excessive alcohol with Clopact A 75 mg/75 mg Tablet as it can irritate your stomach and lead to a stomach ulcer as well.
