Manufacturer: Aaltramed Healthcare Ltd
Salt Composition : Aceclofenac(100mg), Paracetamol(325mg), Serratiopeptidase(15mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Clopaser 100 mg/325 mg/15 mg Tablet should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop.
The mode of action of aceclofenac is largely based on the inhibition to prostaglandin synthesis. Aceclofenac is a potent inhibitor of the enzyme cyclo-oxygenase, which is involved in the production of prostaglandins. After oral administration, aceclofenac is rapidly and completely absorbed as unchanged drug.
Paracetamol has a central analgesic effect that is mediated through activation of descending serotonergic pathways. Debate exists about its primary site of action, which may be inhibition of prostaglandin (PG) synthesis or through an active metabolite influencing cannabinoid receptors.
Serratiopeptidase acts as an anti-inflammatory agent by regulating inflammatory cytokines and hence the onset of chronic inflammation. It significantly modifies cell adhesion molecules that guide inflammatory cells to the sites of inflammation.
Aceclofenac (AC), a phenyl acetic acid derivative, dichloroanilino)phenyl]acetyl}oxy)acetic acid, is a non-steroidal anti-inflammatory drug (NSAID) indicated for the symptomatic treatment of pain and inflammation with a reduced side effect profile, especially gastrointestinal events that are frequently
It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Serratiopeptidase is a proteolytic enzyme prescribed in various specialities like surgery, orthopaedics, otorhinolaryngology, gynaecology and dentistry for its anti-inflammatory, anti-edemic and analgesic effects.
Nausea
Vomiting
Stomach pain
Indigestion
Heartburn
Loss of appetite
Diarrhea
ischaemic heart disease.
peripheral arterial disease.
cerebrovascular disease.
congestive heart failure.
caloric undernutrition.
acute liver failure.
liver problems.
a condition where the body is unable to maintain adequate blood flow called shock.
acetaminophen overdose.
acute inflammation of the liver due to hepatitis C virus.
skin reactions.
muscle and joint pain.
poor appetite.
nausea.
stomach pain.
cough.
blood clotting disturbances.
Clopaser 100 mg/325 mg/15 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Clopaser 100 mg/325 mg/15 mg Tablet.
Information regarding the use of Clopaser 100 mg/325 mg/15 mg Tablet during breastfeeding is not available. Please consult your doctor.
Aceclofenac film-coated tablets are indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Aceclofenac film-coated tablets are supplied for oral administration and should be swallowed whole with a sufficient quantity of liquid.
Acetaminophen or paracetamol helps to reduce fever and to relieve a headache with mild to moderate pain. It is also used with other pain medications to treat low back pain, osteoarthritis, cold, and toothache.
Serratiopeptidase is often used in oral surgery for its anti-inflammatory purpose after impaction surgery, maxillofacial trauma and infections but its use should be limited in cases of abscess due to its fibrinolytic activity.
Ardeparin The risk or severity of bleeding and hemorrhage can be increased when Aceclofenac is combined with Ardeparin.
Arformoterol The risk or severity of hypertension can be increased when Arformoterol is combined with Aceclofenac.
Acenocoumarol. Paracetamol increases the anticoagulant effect of Acenocoumarol. ...
Alcohol. Alcohol (in those who drink heavily) causes severe liver damage when given with Paracetamol. ...
Alectinib. ...
Asparaginase. ...
Atorvastatin. ...
Bedaquiline. ...
Busulfan. ...
Carbamazepine.
skin reactions.
muscle and joint pain.
poor appetite.
nausea.
stomach pain.
cough.
blood clotting disturbances.
Do not chew, crush or break it. Clopaser 100 mg/325 mg/15 mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Clopaser 100 mg/325 mg/15 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Clopaser 100 mg/325 mg/15 mg Tablet affects you.
Avoid consuming alcohol when taking Clopaser 100 mg/325 mg/15 mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clopaser 100 mg/325 mg/15 mg Tablet is to be taken with food.
Q. What is Clopaser 100 mg/325 mg/15 mg Tablet?
It is a combination of three medicines: Aceclofenac, Paracetamol, and Serratiopeptidase. This medication helps in relieving pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.
Q. Is it safe to take Clopaser 100 mg/325 mg/15 mg Tablet?
It is safe to take this medicine for most of the patients. However, in some patients, it may cause unwanted side effects like nausea, vomiting, stomach pain, heartburn, and diarrhea. If you experience any persistent problem due to the medication, inform your doctor as soon as possible.
Q. Can I stop taking Clopaser 100 mg/325 mg/15 mg Tablet when my pain is relieved?
This medicine is usually used for the short term and can be discontinued when your pain is relieved. However, continued taking it if your doctor has advised you to do so.
Q. Can Clopaser 100 mg/325 mg/15 mg Tablet cause nausea and vomiting?
Yes, the use of this medicine can cause nausea and vomiting. In case you experience nausea while taking this medicine, take it with milk, food, or with antacids. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicines without speaking to your doctor.
Q. Can Clopaser 100 mg/325 mg/15 mg Tablet cause dizziness?
Yes, the use of this medicine can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better.
Q. Are there any specific contraindications associated with taking Clopaser 100 mg/325 mg/15 mg Tablet?
The use of this medicine is considered harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). Its use should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcers/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.
Q. Can I take Clopaser 100 mg/325 mg/15 mg Tablet with vitamin B-complex?
Yes, this medicine can be taken with vitamin B-complex preparations. While it helps to relieve pain, vitamin B-complex can help to correct the vitamin deficiency that might be causing your symptoms.
Q. Can the use of Clopaser 100 mg/325 mg/15 mg Tablet cause damage to kidneys?
Yes, long-term use of this medicine can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect them from damage. The use of painkillers lowers the levels of prostaglandins in the body, which leads to kidney damage on long-term use. The use of painkillers is not recommended in patients with underlying kidney disease.
Q. Can I take a higher dose of Clopaser 100 mg/325 mg/15 mg Tablet than recommended?
No, taking a higher than recommended dose can lead to increased chances of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. What are the instructions for storage and disposal of Clopaser 100 mg/325 mg/15 mg Tablet?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
