Clopid AS 75mg / 75mg Tablet (10'S)

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₹24.66

Strip of 10 Tablet

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Clopid AS 75mg/75mg Tablet should be taken with food regularly at a fixed time each day. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. Lifestyle changes like low-fat diet, exercise and not smoking may help this medicine to work better.



Basic Information

Mechanism Of Action

Aspirin inhibits platelet cyclooxygenase by irreversible acetylation, thereby preventing the formation of thromboxane A2 which is a powerful stimulant of platelet aggregation. Clopidogrel, a thienopyridine, acts by inhibiting adenosine receptors, which inhibits the early step of platelet activation


Pharmacokinets

Aspirin is rapidly absorbed in the upper gastrointestinal (GI) tract and results in a measurable inhibition of platelet function within 60 minutes. This antiplatelet effect is associated with prolongation of the bleeding time and inhibition of TXA2-dependent platelet aggregation.

In the liver, approximately 15% of absorbed clopidogrel is metabolized by the cytochrome P450 (CYP) system to generate its active metabolite via a 2-step bioactivation process, whereas the rest 85% is hydrolyzed by carboxylesterase 1 (CES1) to an inactive carboxylic acid derivative.


Side Effects

Abdominal pain

Bruise

Diarrhea

Gastrointestinal bleeding

Increased bleeding tendency

Nosebleeds

Contra Indications

systemic mastocytosis.

low vitamin K levels.

a type of joint disorder due to excess uric acid in the blood called gout.

anemia.

hemophilia.

a decrease in the blood clotting protein prothrombin.

blood clotting disorder - von Willebrand's disease.

decreased blood platelets.

General Information. ...

Bleeding, GI bleeding, intracranial bleeding, peptic ulcer disease, surgery, trauma. ...

Hepatic disease. ...

Renal disease, renal failure, renal impairment. ...

Poor metabolizers. ...

Epidural anesthesia, labor, obstetric delivery, pregnancy, spinal anesthesia. ...

Breast-feeding. ...

Geriatric.

Pregnancy Related Information

Clopid AS 75mg/75mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Clopid AS 75mg/75mg Tablet.


Breast Feeding Related Information

Clopid AS 75mg/75mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

Aspirin and clopidogrel have complementary mechanisms of action to inhibit platelet function. Indications that have been studied include coronary artery disease (CAD), atherosclerotic ischemic stroke, and atrial fibrillation

Interactions

Many thromboembolic events occur in patients taking aspirin. Dual therapy with aspirin and clopidogrel may prove effective at reduction of thromboembolic complications. However, the extent to which these two drugs interact may significantly increase the risk of bleeding in open surgery.


Typical Dosage

Do not chew, crush or break it. Clopid AS 75mg/75mg Tablet is to be taken with food.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Clopid AS 75mg/75mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

You have been prescribed Clopid AS 75mg/75mg Tablet to lower your risk of heart attack and stroke.

Take it with food to avoid an upset stomach.

It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.

Let your doctor know you are taking Clopid AS 75mg/75mg Tablet before undergoing any surgical procedure.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clopid AS 75mg/75mg Tablet is to be taken with food.


FAQs

Q. Why have I been prescribed Clopid AS 75mg/75mg Tablet?

You may have been prescribed Clopid AS 75mg/75mg Tablet if you had a heart attack, were treated with stents in your coronary arteries, or had coronary artery bypass graft surgery (CABG).

Q. Is Clopid AS 75mg/75mg Tablet a blood thinner?

Yes, Clopid AS 75mg/75mg Tablet is a type of blood thinner. It works by preventing platelets (type of blood cells) from sticking together and forming clots. This action of Clopid AS 75mg/75mg Tablet helps in preventing conditions like heart attack or stroke in people with heart disease, who have recently suffered a heart attack or severe heart-related chest pain (unstable angina).

Q. How long do I need to take Clopid AS 75mg/75mg Tablet after stent insertion?

Your doctor will suggest the exact duration for which you may have to take Clopid AS 75mg/75mg Tablet. The duration will be decided after considering various factors like the illness you are being treated for, type of stent inserted, any episodes of bleeding experienced by you during treatment, etc. Usually, Clopid AS 75mg/75mg Tablet is prescribed for a minimum duration of 1 year. However, it is advised to follow your doctor's advice precisely to get maximum benefit of Clopid AS 75mg/75mg Tablet. Do not stop the medication on your own, consult your doctor first. Sudden discontinuation may increase the chances of clot formation in the stent, heart attack and can even lead to death.

Q. Can I drink alcohol while taking Clopid AS 75mg/75mg Tablet?

It is not advised to take alcohol while taking Clopid AS 75mg/75mg Tablet, as alcohol may increase your chance of stomach bleeding. As a result, you may vomit blood (which may be bright red blood or black/dark brown like coffee grounds) or you may have bloody or black tarry stools. Discuss with your doctor if you are not sure.

Q. What is the most important information I need to know about Clopid AS 75mg/75mg Tablet?

Clopid AS 75mg/75mg Tablet may cause serious or life-threatening bleeding. Moreover, you may bruise easily and it may take longer than usual for bleeding to stop even if you have a minor injury like a small cut while shaving. Get emergency medical help if you notice excessive or prolonged bleeding. You should inform your doctor if you notice black tarry stools or if there is blood in the urine. Be vigilant on any signs of stroke such as sudden numbness or weakness (one side or both sides of the body), difficulty walking, mental confusion, slurred speech, dizziness and any unexplained headache. Contact your doctor immediately if you develop any such signs of stroke as stroke is an uncommon side effect of Clopid AS 75mg/75mg Tablet and needs urgent medical attention as it can otherwise be fatal.

Q. Do I need to stop Clopid AS 75mg/75mg Tablet before surgery?

Your doctor will decide whether you need to stop taking Clopid AS 75mg/75mg Tablet before any surgery or treatment or not. Usually, if a surgery or treatment is planned beforehand, the doctor may stop Clopid AS 75mg/75mg Tablet a few days (usually 7 days) before the surgery or treatment owing to the increased risk of bleeding during the procedure. You should not stop taking Clopid AS 75mg/75mg Tablet on your own without discussing it with your doctor.

Q. Who should not take Clopid AS 75mg/75mg Tablet?

Clopid AS 75mg/75mg Tablet is not recommended for people who are allergic to it or any of its ingredients. Do not take Clopid AS 75mg/75mg Tablet if you have or ever had severe liver disease, stomach ulcers, bleeding in the brain (stroke or a transient ischemic attack, also known as TIA), or if you have a bleeding disorder known as hemophilia (disease in which blood does not clot normally). Additionally, avoid taking Clopid AS 75mg/75mg Tablet if you are trying to get pregnant, already pregnant, or breastfeeding.

Q. What if I forget to take a dose of Clopid AS 75mg/75mg Tablet?

If you forget to take a dose of Clopid AS 75mg/75mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Q. What should I avoid while taking Clopid AS 75mg/75mg Tablet?

Avoid activities that may increase your chances of bleeding. Be extra careful while shaving or brushing your teeth to prevent bleeding. Also, you should avoid taking painkillers, but if you need to take one like ibuprofen for joint pain, headache, backache, etc. then consult your doctor first. This is because taking pain killers with Clopid AS 75mg/75mg Tablet may increase your chances of developing a stomach ulcer and bleeding. Refrain from taking excessive alcohol with Clopid AS 75mg/75mg Tablet as it can irritate your stomach and lead to a stomach ulcer as well.