Manufacturer: Cipla Ltd
Salt Composition : Clopidogrel(75mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Clopigard 75mg Tablet is prescribed to people at high risk of heart disease. This includes people with peripheral vascular disease (blood circulation problems due to narrowing of blood vessels), recent heart attack or stroke, irregular heartbeats, and those who have undergone certain heart procedures like stenting. It is also used in combination with some other medicines for the treatment of heart attack and some types of heart-related chest pain (unstable angina).
The active metabolite of clopidogrel selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet P2Y12 receptor and the subsequent ADP- mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation. This action is irreversible
In the liver, approximately 15% of absorbed clopidogrel is metabolized by the cytochrome P450 (CYP) system to generate its active metabolite via a 2-step bioactivation process, whereas the rest 85% is hydrolyzed by carboxylesterase 1 (CES1) to an inactive carboxylic acid derivative.
Bleeding
General Information. ...
Bleeding, GI bleeding, intracranial bleeding, peptic ulcer disease, surgery, trauma. ...
Hepatic disease. ...
Renal disease, renal failure, renal impairment. ...
Poor metabolizers. ...
Epidural anesthesia, labor, obstetric delivery, pregnancy, spinal anesthesia. ...
Breast-feeding. ...
Geriatric.
Clopigard 75mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Caution is advised when consuming alcohol with Clopigard 75mg Tablet. Please consult your doctor.
Clopigard 75mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use during a percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) and stable ischemic heart disease. ...
Primary prevention of thromboembolism atrial fibrillation.
Symptomatic carotid artery stenosis.
Secondary prevention post-coronary artery bypass grafting.
Diabetes drug. In most cases, repaglinide should not be taken with clopidogrel. ...
Stomach acid drugs (proton pump inhibitors) ...
Nonsteroidal anti-inflammatory drugs (NSAIDs) ...
Blood thinners.
Drugs used to treat depression. ...
Salicylates (aspirin) ...
Opioids.
Do not chew, crush or break it. Clopigard 75mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Clopigard 75mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
For best results, take it at the same time every day.
Clopigard 75mg Tablet increases your risk of bleeding. Be careful while shaving, using sharp objects, or cutting fingernails or toenails.
Do not discontinue using the medicine without consulting your doctor as this may increase your chances of having another heart attack or stroke.
If you are scheduled to undergo a surgery or dental treatment, you may be asked to stop taking Clopigard 75mg Tablet temporarily.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clopigard 75mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Clopigard 75mg Tablet used for?
Clopigard 75mg Tablet is used to prevent formation of blood clots, thus reducing the risk of heart attacks or stroke. It facilitates smooth circulation of blood in the body by reducing the ability of the platelets to stick together, that could otherwise lead to formation of harmful clots in hardened blood vessels.
Q. Is Clopigard 75mg Tablet a blood thinner?
Yes, Clopigard 75mg Tablet is an antiplatelet medicine which is also known as a blood thinner. It makes your blood flow more easily through your blood vessels and prevents formation of harmful blood clots. This lowers your chances of heart attack or stroke.
Q. When should you take Clopigard 75mg Tablet?
You should take Clopigard 75mg Tablet exactly as prescribed by the doctor. You can take it with or without food, at any time of the day. However, it is important to take it regularly at the same time each day for best results. This will also help you to remember to take it daily.
Q. Does Clopigard 75mg Tablet affect blood pressure?
Yes, Clopigard 75mg Tablet may rarely cause a decrease in blood pressure as a side effect. However, this is very rare and does not affect everyone. Consult your doctor if you feel dizzy, lightheaded, weak or have a blurred vision. These are signs and symptoms of low blood pressure and therefore, you should contact your doctor immediately.
Q. Who should not take Clopigard 75mg Tablet?
Clopigard 75mg Tablet is not recommended for people who are allergic to it, have severe liver disease, have stomach ulcers, bleeding in the brain, or have a bleeding disorder known as hemophilia (disease in which blood does not clot normally). Additionally, avoid taking Clopigard 75mg Tablet if you are trying to get pregnant, already pregnant, or breastfeeding.
Q. Can I take alcohol with Clopigard 75mg Tablet?
Yes, you can take alcohol with Clopigard 75mg Tablet. However, excessive intake of alcohol should be avoided as it can irritate the inner lining of the stomach and this increases the risk of developing a stomach ulcer later.
Q. Can Omeprazole be taken along with Clopigard 75mg Tablet?
Omeprazole ( a proton pump inhibitor or PPI used to treat and prevent indigestion) may interfere with the working of Clopigard 75mg Tablet and reduce the effect of Clopigard 75mg Tablet. Your doctor may prescribe an alternate PPI like lansoprazole, if you suffer from indigestion or if they judge that it would be beneficial to you. You should let your doctor know about all the medicines that have been prescribed to you before starting Clopigard 75mg Tablet. Always consult your doctor before taking any medicine.
Q. What are the side effects of taking Clopigard 75mg Tablet?
The most common side effect of Clopigard 75mg Tablet is bleeding. This may lead to bruising on the skin, nosebleeds, blood in the urine or stools (black tarry stools), or heavier periods than usual in females. Rarely, bleeding may also occur in the head, eyes, lungs, or joints and may even be severe. In case you have a minor injury, such as a small cut while shaving, bleeding may take longer than usual to stop. Get emergency medical help if the bleeding is profuse, does not stop on it’s own, or bothers you. Other side effects of Clopigard 75mg Tablet that may be seen occasionally in some people include diarrhea, abdominal pain, indigestion or heartburn. Please consult your doctor if any of these side effects persist or worry you.
Q. What will happen if I stop taking Clopigard 75mg Tablet?
If you stop taking Clopigard 75mg Tablet suddenly, your chances of heart attack or stroke may increase. These conditions can be fatal. Do not stop taking it without talking to your doctor, otherwise your condition may worsen. Continue taking Clopigard 75mg Tablet for as long as prescribed by your doctor to get maximum benefit.
Q. How long does it take Clopigard 75mg Tablet to start working? How long do I need to take it?
Clopiogrel starts working within 2 hours of taking it. Continue taking it as long as your doctor has advised you. You may have to take it for a few weeks or months, or you may have to take it for the rest of your life.