Clopixol Depot 200mg Injection

Manufacturer: Lundbeck India Pvt Ltd

Salt Composition : Zuclopenthixol(200mg/ml)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Clopixol Depot Injection is given as an injection under the supervision of a healthcare professional and should not be self-administered. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.



Basic Information

Mechanism Of Action

Zuclopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Zuclopenthixol is a typical antipsychotic neuroleptic drug of the thioxanthene class. It mainly acts by antagonism of D1 and D2 dopamine receptors

Pharmacokinets

The metabolism of zuclopenthixol is mainly by sulphoxidation, side chain N-dealkylation and glucuronic acid conjugation. The metabolites are devoid of pharmacological activity. Primarily in the feces with approximately 10% in the urine. 20 hours (range 12-28 hours) for the tablet form, 19 days for the depot form

Side Effects

Abnormality of voluntary movements

Constipation

Dryness in mouth

Increased prolactin level in blood

Orthostatic hypotension (sudden lowering of blood pressure on standing)

Sleepiness

Tremors

Urinary retention

Weight gain

Contra Indications

Contraindicated in patients with unconsciousness due to alcohol, barbiturate and opiate consumption, porphyria, and hypersensitivity

Pregnancy Related Information

Clopixol Depot Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

Clopixol Depot Injection may cause excessive drowsiness with alcohol.


Breast Feeding Related Information

Clopixol Depot Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

Zuclopenthixol is an antipsychotic indicated for the management of schizophrenia. The acuphase formulation is indicated for initial treatment of acute psychosis or exacerbation of psychosis, while the depot formulation is best for maintenance

Interactions

anticholinergic medications (for example, antispasmodics such as belladonna alkaloids, scopolamine) alpha blockers (e.g., doxazosin, prazosin, terazosin) dopamine agonists

Typical Dosage

 Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

Clopixol Depot Injection is administered into the muscle of the buttock or thigh.

Use caution while driving or doing anything that requires concentration as Clopixol Depot Injection can cause dizziness and sleepiness.

Avoid drinking alcohol while taking this medicine because it can make drowsiness worse.

It may affect how your body regulates your temperature. Avoid situations that can result in your overheating or getting dehydrated.

It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.

Inform your doctor if you experience any swelling, particularly of the face, lips, jaw and tongue and trouble breathing while taking this medicine.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.