Manufacturer: Lancer Health Care Pvt Ltd
Salt Composition : Clobetasol(0.05% w/w), Gentamicin(0.1% w/w), Miconazole(2% w/w)
Tube of 10gm Cream
(Inclusive of all taxes)
Closkin gm Cream is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. Wash your hands before and after the application of the medicine. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure the better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.
Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids. Clobetasol is a Corticosteroid. The mechanism of action of clobetasol is as a Corticosteroid Hormone Receptor Agonist
Gentamicin is bactericidal and is a broad spectrum antibiotic (except against streptococci and anaerobic bacteria). Its mechanism of action involves inhibition of bacterial protein synthesis by binding to 30S ribosomes
Miconazole inhibits the synthesis of ergosterol, a major component of fungal cell membranes. This interferes with the barrier function of the membrane and with membrane-bound enzymes
Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids. Clobetasol is a Corticosteroid. The mechanism of action of clobetasol is as a Corticosteroid Hormone Receptor Agonist
Gentamicin is bactericidal and is a broad spectrum antibiotic (except against streptococci and anaerobic bacteria). Its mechanism of action involves inhibition of bacterial protein synthesis by binding to 30S ribosomes
Miconazole inhibits the synthesis of ergosterol, a major component of fungal cell membranes. This interferes with the barrier function of the membrane and with membrane-bound enzymes
Application site reactions (burning, irritation, itching and redness)
Thinning of skin
Corticosteroid hypersensitivity.
Cushing's syndrome, hepatic disease, hypothalamic-pituitary-adrenal (HPA) suppression, occlusive dressing, skin abrasion.
Diabetes mellitus.
Children, growth inhibition, increased intracranial pressure, infants, neonates.
Pregnancy.
Breast-feeding.
low amount of calcium in the blood.
dehydration.
a type of movement disorder called parkinsonism.
myasthenia gravis, a skeletal muscle disorder.
ringing in the ears.
disorder of nerve that controls hearing and balance.
decreased kidney function.
sensation of spinning or whirling.
Burning, irritation, abdominal cramps, allergic contact dermatitis, itching, stinging, maceration, erythema. With oral dose- diarrhoea, nausea, headache, dysgeusia, upper abdominal pain, vomiting.
Closkin gm Cream is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
No interaction found/established
Closkin gm Cream is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Clobetasol has no known severe interactions with other drugs.
Clobetasol has no known serious interactions with other drugs.
Clobetasol has no known moderate interactions with other drugs.
Clobetasol has no known mild interactions with other drugs.
dehydration.
neuromuscular blockade.
ototoxicity.
renal dysfunction.
Miconazole oral has no listed severe interactions with other drugs. Miconazole oral has no listed serious interactions with other drugs. Miconazole oral has no listed moderate interactions with other drugs.
Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Store below 30°C
If you miss a dose of Closkin gm Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Your doctor has prescribed Closkin gm Cream to cure your infection and improve symptoms.
Some tips for personal hygiene:
Wash your hands with soap before and after applying the cream.
Do not share your towel or clothes with anyone.
Wear clean clothes every day to prevent infection.
You may have to use it for a long time before your skin infection starts to improve. Be patient and keep using it every day.
Avoid getting it in the eyes, nose, or mouth. If accidental exposure occurs, rinse immediately with plenty of water.
If you think the area of skin you are treating has become more irritated and infected, you should stop using Closkin gm Cream and consult your doctor.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Q. How to use Closkin gm Cream?
Closkin gm Cream should be used as advised by the doctor or as per the instructions on the label of the medicine. Apply a thin layer to cover the affected areas. The dose would depend on the condition for which it is prescribed. Wash your hands after using this medicine unless it is used for treating infection of the hands. Avoid any contact with the eyes.
Q. Can I stop taking Closkin gm Cream when my symptoms are relieved?
No, do not stop using Closkin gm Cream and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.
Q. What are the precautions that need to be taken while using Closkin gm Cream?
Closkin gm Cream should not be used on the face and contact with eyes should be avoided. Do not apply a bandage or dressing on the area being treated, as this will increase absorption of the medicine and increase the risk of side effects. This medicine should only be used for the condition it is prescribed for. Do not use it for any other condition without consulting your doctor. Do not give it to other people even if their condition appears to be the same.
Q. What would happen if I use a higher than the recommended dose of Closkin gm Cream for long periods?
The dosage and duration of using Closkin gm Cream should be strictly according to the doctor’s advice. This medicine contains clobetasol which when used in higher doses and for longer periods can get absorbed in the blood circulation and cause adrenal suppression and Cushing's syndrome. It can cause weight gain, high blood pressure and rounding of the face. Its application can cause a change in color of skin at the site of application. Veins beneath the skin become visible due to the thinning and weakening of the skin. There could be an increased hair growth. If you experience an increased severity of your symptoms, please consult your doctor for re-evaluation.
Q. What are the instructions for the storage and disposal of Closkin gm Cream?
Keep this medicine in the packet or the container it came in. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. What are the contraindications associated with the use of Closkin gm Cream?
Use of Closkin gm Cream is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine. Avoid its use in case of any fungal infections (ringworm or athlete's foot), viral infections (herpes or chickenpox). It should also be avoided in the treatment of acne or rosacea. Consult your doctor before using it for any condition.
