Manufacturer: Clyde Biotech P Ltd
Salt Composition : Alprazolam(0.25mg), Fluoxetine(20mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Cnl Plus 0.25 mg/20 mg Tablet is taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as this may cause nausea, anxiety, dysphoria, and agitation.
The exact mechanism of action of alprazolam is unknown. Benzodiazepines bind to gamma aminobutyric acid (GABA) receptors in the brain and enhance GABA-mediated synaptic inhibition; such actions may be responsible for the efficacy of alprazolam in anxiety disorder and panic disorder
Presynaptic serotonin (5HT1A) receptors are in the dorsal raphe nucleus and project to the prefrontal cortex. Fluoxetine exerts its effects by blocking the reuptake of serotonin into presynaptic serotonin neurons by blocking the reuptake transporter protein located in the presynaptic terminal
Plasma levels are proportionate to the dose given; over the dose range of 0.5 to 3.0 mg, peak levels of 8.0 to 37 ng/mL were observed. Using a specific assay methodology, the mean plasma elimination half-life of alprazolam has been found to be about 11.2 hours (range: 6.3-26.9 hours) in healthy adults
Fluoxetine has a nonlinear pharmacokinetic profile. Therefore, the drug should be used with caution in patients with a reduced metabolic capability (i.e. hepatic dysfunction). In contrast with its effect on the pharmacokinetics of other antidepressants, age does not affect fluoxetine pharmacokinetics.
Nausea
Vomiting
Diarrhea
Confusion
Memory impairment
Uncoordinated body movements
Drowsiness
Tiredness
Anorgasmia (decreased orgasm)
Delayed ejaculation
Low sexual desire
overweight.
suicidal thoughts.
alcohol intoxication.
drug abuse.
depression.
wide-angle glaucoma.
closed angle glaucoma.
asthma.
diabetes.
a disorder with excess antidiuretic hormone called syndrome of inappropriate antidiuretic hormone.
low amount of sodium in the blood.
an increased risk of bleeding.
manic behavior.
a form of mania that has a lower severity of symptoms.
manic-depression.
suicidal thoughts.
Cnl Plus 0.25 mg/20 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Cnl Plus 0.25 mg/20 mg Tablet.
Cnl Plus 0.25 mg/20 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Alprazolam is frequently prescribed to manage panic and anxiety disorders. Alprazolam has also been misused for recreational purposes because of its disinhibition, euphoria, and anxiolytic effects. FDA-labeled indications include anxiety disorders and panic disorders with or without agoraphobia
Fluoxetine is indicated for both acute and maintenance treatment of major depressive disorder, obsessive compulsive disorder, and bulimia nervosa; however, it is only indicated for acute treatment of panic disorder independent of whether agoraphobia is present
carbamazepine.
cimetidine.
clarithromycin.
erythromycin base.
erythromycin ethylsuccinate.
erythromycin lactobionate.
erythromycin stearate.
idelalisib.
The major fluoxetine-drug interactions involve the amino acids L-dopa and L-tryptophan, anorexiants, anticonvulsants, antidepressants, anxiolytics, calcium channel blockers, cyproheptadine, lithium salts, and drugs of abuse. The underlying mechanism and the paradoxical effects of fluoxetine are addressed
Do not chew, crush or break it. Cnl Plus 0.25 mg/20 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Cnl Plus 0.25 mg/20 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Cnl Plus 0.25 mg/20 mg Tablet is prescribed for the treatment of depression.
It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
Do not stop taking Cnl Plus 0.25 mg/20 mg Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Inform your doctor if you are taking any other antidepressant.
Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
Avoid alcohol while taking Cnl Plus 0.25 mg/20 mg Tablet.
If you have diabetes, you will be asked to monitor your blood glucose level regularly as Cnl Plus 0.25 mg/20 mg Tablet may affect the levels of sugar in your blood.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cnl Plus 0.25 mg/20 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
