Manufacturer: Novartis India Ltd
Salt Composition : Valsartan(80mg), Hydrochlorothiazide(12.5mg)
You can take CO Diovan Fct 80mg/12.5mg Tablet with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase.
Valsartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland.
Hydrochlorothiazide inhibits sodium chloride transport in the distal convoluted tubule. More sodium is then excreted in the kidney with accompanying fluid. Pharmacological effects begin in about 2 hours after an oral dose, peak in 4 hours, and lasts for about 6 to 12 hours
Valsartan is an orally active, potent, and specific angiotensin II type 1 (AT 1) receptor blocker (3). The AT 1 receptor mediates all known cardiovascular actions of angiotensin II, including vasoconstriction, aldosterone secretion, and sympathetic stimulation.
Absorption of hydrochlorothiazide is reduced in patients with congestive heart failure. Peak plasma concentrations are observed within 1 to 5 hours of dosing, and range from 70 to 490 ng/mL following oral doses of 12.5 to 100 mg.
Nausea
Taste change
Diarrhea
Upset stomach
Dizziness
Decreased blood pressure
Headache
Fatigue
Increased blood lipid level
Electrolyte imbalance
Increased blood uric acid
Glucose intolerance
low amount of sodium in the blood.
high levels of potassium in the blood.
low levels of a type of white blood cell called neutrophils.
renal artery stenosis.
low blood pressure.
liver problems.
severe renal impairment.
pregnancy.
sympathectomy.
diabetes.
increased activity of the parathyroid gland.
high cholesterol.
a type of joint disorder due to excess uric acid in the blood called gout.
low amount of magnesium in the blood.
high amount of calcium in the blood.
low amount of sodium in the blood.
CO Diovan Fct 80mg/12.5mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with CO Diovan Fct 80mg/12.5mg Tablet.
CO Diovan Fct 80mg/12.5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Indicated for the treatment of hypertension, to lower blood pressure in adults and pediatric patients six years of age and older. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
Indicated as adjunctive therapy to treat edema associated with congestive heart failure, hepatic cirrhosis, corticosteroid, and estrogen therapy.
Indicated to treat edema associated with renal dysfunction.
Indicated to treat hypertension as a sole agent or adjunct.
Barbiturates. If you take these drugs with hydrochlorothiazide, your blood pressure may be lowered too much. ...
Lithium. ...
Blood pressure drugs. ...
Cholesterol-lowering drugs. ...
Corticosteroids. ...
Diabetes drugs. ...
Narcotics. ...
Nonsteroidal anti-inflammatory drugs (
Do not chew, crush or break it. CO Diovan Fct 80mg/12.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of CO Diovan Fct 80mg/12.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed CO Diovan Fct 80mg/12.5mg Tablet for the treatment of high blood pressure.
It can be taken with or without food.
CO Diovan Fct 80mg/12.5mg Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Use of CO Diovan Fct 80mg/12.5mg Tablet during pregnancy or breastfeeding is unsafe.
It may also decrease the risk of stroke and heart attacks.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. CO Diovan Fct 80mg/12.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. How long does it take for CO Diovan Fct 80mg/12.5mg Tablet to start working?
A substantial decrease in blood pressure can be experienced within 2 weeks of starting CO Diovan Fct 80mg/12.5mg Tablet. However, the medicine may take up to 4 weeks to show its complete effects. Talk to your doctor in case you have any concerns regarding CO Diovan Fct 80mg/12.5mg Tablet, but do not stop taking it without consulting the doctor.
Q. Which medicine is considered safe for treating high blood pressure?
There are many blood pressure-lowering medicines which can be considered safe. The doctor will advise the exact use of these medicines, keeping various factors such as age, gender, other coexisting diseases, etc. into consideration. Also, the effect of the medicine and response of the patient can vary from person to person. For instance, a person below 55 years of age having no other co-existing disease may be prescribed angiotensin II receptor antagonists (ARAs) (e.g., CO Diovan Fct 80mg/12.5mg Tablet, losartan, olmesartan) or Angiotensin Converting Enzyme (ACE) Inhibitors (e.g., ramipril, captopril or enalapril) by the doctor.
Q. Is CO Diovan Fct 80mg/12.5mg Tablet bad for kidneys?
CO Diovan Fct 80mg/12.5mg Tablet does not generally affect the working of a proper functioning kidney. However, there is limited data to support the safety of patients who have existing severe kidney impairment (creatinine clearance <10 ml/min) and are on dialysis. Hence, CO Diovan Fct 80mg/12.5mg Tablet should be used cautiously in such patients. It should only be used when advised by the doctor.
Q. Who should not be given CO Diovan Fct 80mg/12.5mg Tablet?
CO Diovan Fct 80mg/12.5mg Tablet should not be given to patients who are allergic to it, have severe liver disease, have diabetes or impaired kidney function. Also, its use should be restricted if you are being treated with blood pressure lowering medicine containing Aliskiren. In addition to that, CO Diovan Fct 80mg/12.5mg Tablet should not be used if you are pregnant or trying to conceive. If you are not sure or have any queries, consult your doctor.
