Manufacturer: Marc Laboratories Pvt Ltd
Salt Composition : Chlorpheniramine Maleate(4mg/5ml), Codeine(10mg/5ml), Menthol(0.1mg/5ml)
Bottle of 100ml Syrup
(Inclusive of all taxes)
Codimarc T Syrup is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
This medication works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. By blocking another natural substance made by your body (acetylcholine), it helps dry up some body fluids to relieve symptoms such as watery eyes and runny nose
Codeine phosphate is an opioid analgesic with uses similar to those of morphine, but is much less potent as an analgesic. Its primary site of action is at the mu opioid receptors distributed throughout the central nervous system. The sedative activities of codeine are less potent than those of morphine
Menthol is a selective activator of transient receptor potential melastatin-8 (TRPM8) channels and is also a vasoactive compound. As a topical agent, it acts as a counter-irritant by imparting a cooling effect and by initially stimulating nociceptors and then desensitizing them.
In conclusion, the pharmacokinetics of codeine were similar to other opioids in dogs with a short half-life, rapid clearance, large volume of distribution, and poor oral bioavailability. High concentrations of codeine-6-glucuronide were detected after IV and oral administration.
Chlorpheniramine has a serum half-life of approximately 20 hours in adults, and elimination from the body is primarily by metabolism to monodesmethyl and didesmethyl compounds. The half-life is increased in the presence of renal dysfunction and decreased in children
Some studies show that menthol acts as GABAA receptor positive allosteric modulator and increases Gabaergic transmission in PAG neurons. Menthol also shares anaesthetic properties similar to propofol, by modulating the same sites of the GABAA receptor.
Nausea
Vomiting
Constipation
Sleepiness
Lightheadedness
Dizziness
Breathlessness
Sweating
glucose-6-phosphate dehydrogenase (G6PD) deficiency.
methemoglobinemia, a type of blood disorder.
abnormal heart rhythm.
decreased lung function.
seizures.
large open wound.
anemia from pyruvate kinase and G6PD deficiencies.
burns.
overactive thyroid gland.
closed angle glaucoma.
high blood pressure.
stenosing peptic ulcer.
blockage of the stomach or intestine.
blockage of the urinary bladder.
enlarged prostate.
an inability to completely empty the bladder.
Hypersensitivity reaction to codeine or any component of the formulation.
Respiratory depression due to comorbid respiratory disorder.
Children less than 12 years of age.
Pediatric patients with a history of tonsillectomy or adenoidectomy.
Paralytic ileus.
Intestinal obstruction.
Codimarc T Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Codimarc T Syrup may cause excessive drowsiness with alcohol.
Codimarc T Syrup is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
This medication is used to treat minor aches and pains of the muscles/joints (such as arthritis, backache, sprains). Menthol works by causing the skin to feel cool and then warm. These feelings on the skin distract you from feeling the aches/pains deeper in your muscles and joints
Its main indication is for pain and cough. Codeine plays a role in the treatment of mild to moderate pain. Its use is recognized in chronic pain due to ongoing cancer and palliative care. However, the use of codeine to treat other types of chronic pain remains controversial
Chlorpheniramine relieves red, itchy, watery eyes; sneezing; itchy nose or throat; and runny nose caused by allergies, hay fever, and the common cold. Chlorpheniramine helps control the symptoms of cold or allergies but will not treat the cause of the symptoms or speed recovery
Using codeine together with chlorpheniramine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.
Menthol topical has no listed severe interactions with other drugs. Menthol topical has no listed serious interactions with other drugs. Menthol topical has no listed moderate interactions with other drugs. Menthol topical has no listed mild interactions with other drugs.
Shake well before use. Codimarc T Syrup may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Codimarc T Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Codimarc T Syrup is prescribed to get relief from a dry cough.
Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.
Inform your doctor if you have a history of stomach ulcers or asthma.
Consult your doctor if you do not see any improvement and have cough for more than 7 days.
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Codimarc T Syrup may be taken with or without food, but it is better to take it at a fixed time.
