Manufacturer: Torque Pharmaceuticals Pvt Ltd
Salt Composition : Ammonium Chloride(60mg/5ml), Chlorpheniramine Maleate(2.5mg/5ml), Dextromethorphan Hydrobromide(5mg/5ml), Guaifenesin(50mg/5ml)
Bottle of 100ml Syrup
(Inclusive of all taxes)
Cofmac Syrup is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
Cofmac Syrup is a combination of four medicines: Ammonium chloride, chlorpheniramine, dextromethorphan and guaifenesin which relieves cough. Ammonium chloride and guaifenesin are expectorants which decrease the stickiness of mucus (phlegm) and help in its removal from the airways.
Ammonium chloride increases acidity by increasing the amount of hydrogen ion concentrations. Ammonium chloride can be used as an expectorant due to its irritative action on the bronchial mucosa. This effect causes the production of respiratory tract fluid which in order facilitates the effective cough.Chlorpheniramine has a serum half-life of approximately 20 hours in adults, and elimination from the body is primarily by metabolism to monodesmethyl and didesmethyl compounds. The half-life is increased in the presence of renal dysfunction and decreased in children.Following oral administration, dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood–brain barrier.Guaifenesin is administered orally. The plasma half-life is approximately 1 hour. Guiafenesin is rapidly hydrolyzed (60% within seven hours) and then excreted in the urine, with beta-(2-methoxyphenoxy)-lactic acid as its major urinary metabolite. No unchanged drug was detected in the urine following administration.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cofmac
Nausea
Upset stomach
Diarrhea
Stomach pain
Vomiting
Allergic reaction
Sleepiness
Dizziness
Headache
Rash
Hives
Hypersensitivity to Cofmac Syrup is a contraindication. In addition, Cofmac Syrup should not be used if you have the following conditions:
Allergic reactions
Blockage of urinary bladder
Breastfeeding
Breathing difficulty
Cannot empty bladder
Chronic difficulty having a bowel movement
Chronic obstructive lung disease
Closed angle glaucoma
Concomitant use with a monoamine oxidase inhibitor
Enlarged prostate
Cofmac Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Cofmac Syrup. Please consult your doctor.
Cofmac Syrup is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Ammonium chloride, chlorpheniramine, dextromethorphan and guaifenesin which relieve cough. Ammonium chloride and guaifenesin are expectorants which decrease the stickiness of mucus (phlegm) and help in its removal from the airways. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Dextromethorphan is a cough suppressant that relieves cough by reducing the activity of cough centre in the brain.
If you use other drugs or over the counter products at the same time, the effects of Cofmac Syrup may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Cofmac Syrup may interact with the following drugs and products:
Alcohol
Amiodarone
Antidepressants
Cough and cold medicines
Diazepam
Haloperidol
Methadone
Monoamine oxidase inhibitors
Nitrazepam
Phenelzine
Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Cofmac Syrup may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Cofmac Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
If you are diabetic, monitor your blood glucose regularly while taking this medicine.
Inform your doctor if you have a history of thyroid or heart disease.
Stop taking Cofmac Syrup and inform your doctor if your cough persists for more than 1 week, tends to recur, or is accompanied by a fever, rash or persistent headache.
Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Cofmac Syrup may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Cofmac Syrup?
Cofmac Syrup is a combination of four medicines: Ammonium chloride, chlorpheniramine, dextromethorphan and guaifenesin which relieves cough. Ammonium chloride and guaifenesin are expectorants which decrease the stickiness of mucus (phlegm) and help in its removal from the airways. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Dextromethorphan is a cough suppressant that relieves cough by reducing the activity of cough center in the brain.
Q. Can the use of Cofmac Syrup cause dryness in mouth?
Yes, the use of Cofmac Syrup can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.
Q. Can the use of Cofmac Syrup cause dizziness?
Yes, the use of Cofmac Syrup can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
Q. Can the use of Cofmac Syrup cause diarrhea?
Yes, the use of Cofmac Syrup can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids by taking small frequent sips. Also, avoid taking fatty or fried foods along with this medication. Talk to your doctor if diarrhea persists and you notice signs of dehydration, like less urination with dark colored and strong-smelling urine. Do not take any other medicine without speaking to your doctor.
Q. Can the use of Cofmac Syrup cause nausea and vomiting?
Yes, the use of Cofmac Syrup can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and if you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Q. What is the recommended storage condition for Cofmac Syrup?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
