Coftrit Syrup (100ml)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

₹39.90

Bottle of 100ml Syrup

(Inclusive of all taxes)


Coftrit Syrup is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.


Basic Information

Mechanism Of Action

Coftrit Syrup is a combination of three medicines: Phenylpropanolamine, Chlorpheniramine Maleate and Dextromethorphan Hydrobromide which relieve dry cough. Phenylpropanolamine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose.

Pharmacokinets

The drug was shown to be rapidly absorbed with a mean tmaxof 1.47 ± 0.49 h and a mean elimination half-life of 4.0 ± 0.5 h. Phenylpropanolamine is predominantly excreted via the kidney with a mean renal clearance of 0.646 ± 0.089 liter/kg/h and 90.2 ± 1.7% excreted unchanged in the urine.Chlorpheniramine has a serum half-life of approximately 20 hours in adults, and elimination from the body is primarily by metabolism to monodesmethyl and didesmethyl compounds. The half-life is increased in the presence of renal dysfunction and decreased in children.Following oral administration, dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood–brain barrier.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Coftrit

Nausea

Upset stomach

Insomnia (difficulty in sleeping)

Palpitations

Sleepiness

High blood pressure

Contra Indications

Hypersensitivity to Coftrit Syrup is a contraindication. In addition, Coftrit Syrup should not be used if you have the following conditions:

Glaucoma

Hypersensitivity

Hypersensitivity to dextromethorphan

Hypertension

Hyperthyroidism

Intestinal obstruction

Monoamine oxidase inhibitors

Prostatic hypertrophy

Pregnancy Related Information

Coftrit Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

Caution is advised when consuming alcohol with Coftrit Syrup. Please consult your doctor.


Breast Feeding Related Information

Information regarding the use of Coftrit Syrup during breastfeeding is not available. Please consult your doctor.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Phenylpropanolamine+Chlorpheniramine Maleate+Dextromethorphan Hydrobromide is used in the treatment of dry cough.Phenylpropanolamine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Dextromethorphan is a cough suppressant that relieves cough by reducing the activity of cough centre in the brain.

Interactions

If you use other drugs or over the counter products at the same time, the effects of Coftrit Syrup may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Coftrit Syrup may interact with the following drugs and products:

Acebutolol

Alcohol

Antipsychotics

Atropine

Bromocriptine

Debrisoquine

Doxepin

Ephedrine

Furazolidone

Guanethidine

Typical Dosage

Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Coftrit Syrup may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Coftrit Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Coftrit Syrup is prescribed to get relief from a dry cough.

Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.

Consult your doctor if you do not see any improvement and have a cough for more than 7 days.

Let your doctor know if you are taking any anti-depressants.

Inform your doctor if you have had a cough for a long time or if you have asthma or suffer from serious asthma attacks, or if your cough is accompanied by a fever, rash, or persistent headache.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Coftrit Syrup may be taken with or without food, but it is better to take it at a fixed time.