Manufacturer: Torque Pharmaceuticals Pvt Ltd
Salt Composition : Chlorpheniramine Maleate(1mg), Paracetamol(125mg), Phenylephrine(2.5mg)
Packet of 15ml Drop
(Inclusive of all taxes)
Give Cold GO Drop to your child by mouth with or without food. Children often have a sensitive stomach and complain of stomach upset while taking medicines. Prefer giving this medicine with food if this happens. Always remember that the dosing schedule provided by your child’s doctor depends on the type of symptoms your child has, so make sure to follow the prescribed dose, time, and way strictly.
Give Cold GO Drop at a fixed time each day so that it gradually makes a place in your child’s daily routine, which will help you to remember. If your child vomits within 30 minutes of taking this medicine give the same dose again. However, never repeat the dose if it's already time for the next dose. Your child may start to feel better within a week of regular dosing. However, you must continue giving the medicine to your child to finish the complete prescribed course as stopping it abruptly may worsen your child’s condition.
Chlorpheniramine helps control the symptoms of cold or allergies but will not treat the cause of the symptoms or speed recovery. Chlorpheniramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.
Phenylephrine is an agonist of α1-adrenoceptors. Nasal decongestant action is mediated by activation of α1-adrenoceptors in the arterioles of the nasal mucosa. This causes vasoconstriction, which leads to decreased edema and increased drainage of the sinus cavities.
Paracetamol has a central analgesic effect that is mediated through activation of descending serotonergic pathways. Debate exists about its primary site of action, which may be inhibition of prostaglandin (PG) synthesis or through an active metabolite influencing cannabinoid receptors
Phenylephrine is readily and completely absorbed from the gastro-intestinal tract after oral administration . It is subject to extensive presystemic metabolism in the gut wall and therefore has a systemic bioavailability of approximately 40% relative to intravenous dosing
Chlorpheniramine has a serum half-life of approximately 20 hours in adults, and elimination from the body is primarily by metabolism to monodesmethyl and didesmethyl compounds. The half-life is increased in the presence of renal dysfunction and decreased in children
It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Diarrhea
Rash
Nausea
Vomiting
Allergic reaction
Sleepiness
Headache
Dizziness
MAO inhibitor use w/in 14 days, Urinary retention, CAD, Uncontrolled or severe HTN. Caution if HTN, arrhythmias, cardiovascular disease, diabetes mellitus, angle-closure glaucoma, hyperthyroidism, renal impairment, PKU (phenylalanine-containing forms),
overactive thyroid gland.
closed angle glaucoma.
high blood pressure.
stenosing peptic ulcer.
blockage of the stomach or intestine.
blockage of the urinary bladder.
enlarged prostate.
an inability to completely empty the bladder
caloric undernutrition.
acute liver failure.
liver problems.
a condition where the body is unable to maintain adequate blood flow called shock.
acetaminophen overdose.
acute inflammation of the liver due to hepatitis C virus.
7 YEARS
This medication is an antihistamine, prescribed for allergic conditions such as itchy and watery eyes, sneezing, runny nose, hay fever and common cold. It may also be used to relieve the itching from insect bites and bee stings.
The FDA-approved indication for intravenous (IV) phenylephrine hydrochloride is for increasing blood pressure in adults with clinically significant hypotension resulting primarily from vasodilation in such settings as septic shock or anesthesia.
Paracetamol is a mild analgesic and antipyretic, and is recommended for the treatment of most painful and febrile conditions, for example, headache including migraine, toothache, neuralgia, colds and influenza, sore throat, backache, rheumatic pain and dysmenorrhoea
iobenguane
isocarboxazid.
linezolid.
phenelzine.
procarbazine.
selegiline transdermal.
tranylcypromine.
eluxadoline.
idelalisib.
isocarboxazid.
ivacaftor.
sodium oxybate.
tranylcypromine.
Arguably, the most important pharmacodynamic drug interaction with paracetamol is that of N-acetylcysteine in attenuating the hepatotoxicity that results from supratherapeutic intake and overdose of paracetamol. The role of N-acetylcysteine in managing paracetamol overdose is well established.
Cold GO Drop may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
Do not panic. Unless your child’s doctor has advised a specific regime for your child, you can give the missed dose as soon as you remember it. Skip the missed dose if it’s almost the time for the next dose. Follow the prescribed dosing schedule and do not give a double dose to catch up with the missed dose.
Consult a doctor before taking any medicines.
Cold GO Drop may make your child feel sleepy. Ensure your child takes extra care when taking part in physical activities.
Never combine Cold GO Drop with other cold and flu medicines as that may lead to side effects.
Stop Cold GO Drop and immediately report to the doctor if your child develops an itchy rash, facial swelling, or breathing difficulties.
Practice self-care tips:
Clean and disinfect surfaces after sneezing and coughing to avoid allergy
Give your child plenty of fluids as it helps to thin and to loosen the mucus in the lungs
Restrain your child from having dairy products, coffee, and foods that are spicy and fried. All these can trigger coughing
Make your child gargle with warm saltwater
Ensure your child takes enough rest.
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a marked dropper and take it as directed. Cold GO Drop may be taken with or without food, but it is better to take it at a fixed time.
Q. What if I give too much Cold GO Drop by mistake?
Prolonged or excess intake of Cold GO Drop can put your child at risk of developing serious side effects like seizures, rapid heart rate, /depression, cognition defects and inability to concentrate. Always stick to the prescribed dose. To pour out the right dose, use the calibrated cup provided with the medicine by the manufacturer. Do not use a kitchen teaspoon as it will not give the correct estimate.
Q. How can I store Cold GO Drop?
Cold GO Drop should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all medicines out of the reach and sight of children to avoid any accidental intake.
Q. My child has a cough and fever. Can I give him two medicines together?
Do not give your child more than one cough or cold medicine at a time unless advised by the doctor. The reason being, both the medicines could have the same ingredients. This would be equivalent to an overdose and could have serious implications on your child. Always consult your child’s doctor before giving any medicine to your child.
Q. Can I give my cough medicine to my child?
Never give your child the medicines that have been recommended for use by adults. Children should only be given the medicines specifically formulated for them, else it may cause unwanted side effects. Check the label of the medicine properly before use in your child. Give the medicine to your child in the prescribed dose specifically. It is best to take your child to the doctor if the symptoms are bothersome or fail to improve even after treatment.
Q. Can Cold GO Drop make my child sleepy?
Cold GO Drop may cause mild drowsiness effect, making your child feel sleepy. So, be cautious and never give this medicine to induce sleep. Forced sleep could mask any underlying sleep disorder like insomnia. It’s always best to consult your child’s doctor before giving this medicine to your child.
