Manufacturer: Cure Quick Pharmaceuticals
Salt Composition : Cetirizine(2.5mg/5ml), Paracetamol(125mg/5ml), Phenylephrine(2.5mg/5ml)
Bottle of 50ml Suspension
(Inclusive of all taxes)
Give Cold-P Plus Suspension to your child by mouth with or without food. If your child develops a stomach upset, prefer giving it with food. Always remember that the dosing schedule provided by your child’s doctor depends on the type of symptoms your child has, so make sure to follow the prescribed dose, time, and way strictly.
Give Cold-P Plus Suspension at a fixed time each day so that it gradually makes a place in your child’s daily routine, which will help you to remember. If your child vomits within 30 minutes of taking this medicine give the same dose again. However, never repeat the dose if it's already time for the next dose. Your child may start to feel better within a week of regular dosing. However, you must continue giving the medicine to your child to finish the complete prescribed course as stopping it abruptly may worsen your child’s condition.
Some of the minor and temporary side effects that your child may experience while taking this medicine include nausea, vomiting, diarrhea, dry mouth and nose, dizziness, drowsiness, headache, fatigue, restlessness, insomnia, rapid heart rate, and rash. Usually, these episodes subside once your child’s body adapts to the medicine. In case these side effects persist or become bothersome for your child, consult your child’s doctor without any delay.
Narrate your child’s complete medical history to your child’s doctor, including any ongoing medicine regime or history of any allergy, heart problem, blood disorder, birth defects, airway obstruction, lung anomaly, skin disorder, liver impairment, and kidney malfunction. This information is critical for dose alterations and for planning your child’s overall treatment.
Cetirizine inhibits the allergic symptoms produced by histamines (a certain chemical substance which is released by the body). Phenylephrine acts by constricting the arterioles of the nasal mucosa and helps in nasal decongestion.
The pharmacokinetics of cetirizine have been found to increase linearly with dose across a range of 5 to 60 mg. Its Cmax following a single dose has been found to be 257 ng/mL for 10 mg and 580 ng/mL for 20 mg
It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates
Phenylephrine is readily and completely absorbed from the gastro-intestinal tract after oral administration . It is subject to extensive presystemic metabolism in the gut wall and therefore has a systemic bioavailability of approximately 40% relative to intravenous dosing.
Nausea
Vomiting
Diarrhea
Dryness in mouth
Dry nose
Dizziness
Drowsiness
Headache
Fatigue
Restlessness
Insomnia (difficulty in sleeping)
Increased heart rate
Rash
Contraindications : MAO inhibitor use w/in 14 days, Urinary retention, CAD, Uncontrolled or severe HTN. Caution if HTN, arrhythmias, cardiovascular disease, diabetes mellitus, angle-closure glaucoma, hyperthyroidism, renal impairment, PKU (phenylalanine-containing forms), in pts <6 yo.
caloric undernutrition.
acute liver failure.
liver problems.
a condition where the body is unable to maintain adequate blood flow called shock.
acetaminophen overdose.
acute inflammation of the liver due to hepatitis C virus.
Cetirizine is contraindicated in anyone with a known hypersensitivity to it or any of its ingredients. Cetirizine is also contraindicated in anyone with a known hypersensitivity to hydroxyzine, as cetirizine is a metabolite of hydroxyzine
7 YEARS
The FDA-approved indication for intravenous (IV) phenylephrine hydrochloride is for increasing blood pressure in adults with clinically significant hypotension resulting primarily from vasodilation in such settings as septic shock or anesthesia
Paracetamol is a mild analgesic and antipyretic, and is recommended for the treatment of most painful and febrile conditions, for example, headache including migraine, toothache, neuralgia, colds and influenza, sore throat, backache, rheumatic pain and dysmenorrhoea
Cetirizine is indicated for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria in adults and children 6 months of age and older. It markedly reduces the occurrence, severity, and duration of hives and significantly reduces pruritus
iobenguane
isocarboxazid.
linezolid.
phenelzine.
procarbazine.
selegiline transdermal.
tranylcypromine
Despite its frequent coadministration with other drugs and widespread use, very few clinically significant drug interactions have been documented with paracetamol. Drugs that alter gastric emptying can alter paracetamol pharmacokinetics, but this does not result in toxicity in therapeutic use
bosutinib.
clobazam.
crizotinib.
daclatasvir.
eliglustat.
hyaluronidase.
lomitapide.
lurasidone.
Measure it with a measuring cup and take it by mouth. Shake well before use. Cold-P Plus Suspension may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
Do not panic. Unless your child’s doctor has advised a specific regime for your child, you can give the missed dose as soon as you remember it. Skip the missed dose if it’s almost the time for the next dose. Follow the prescribed dosing schedule and do not give a double dose to catch up with the missed dose.
Consult a doctor before taking any medicines
Do not give Cold-P Plus Suspension if your child is less than 2 years of age. Consult your child’s doctor before giving such medicines.
Cold-P Plus Suspension may make your child feel sleepy. Ensure your child takes extra care when taking part in physical activities.
Never combine Cold-P Plus Suspension with other cold and flu medicines as that may lead to side effects.
Stop Cold-P Plus Suspension and immediately report to the doctor if your child develops an itchy rash, facial swelling, or breathing difficulties.
Practice self-care tips:
Clean and disinfect surfaces after sneezing and coughing to avoid allergy.
Give your child plenty of fluids as it helps to thin and loosen the mucus accumulated in the lungs.
Restrain your child from having caffeinated products and foods that are spicy and fried. All these can trigger coughing.
Make your child gargle with warm saltwater.
Ensure your child takes enough rest.
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Cold-P Plus Suspension may be taken with or without food, but it is better to take it at a fixed time.
Q. What should parents do if infants and children under 2 years of age experience cough and cold symptoms?
A cold is a respiratory illness that is usually self-limited and lasts about a week. If you are concerned about making your child feel more comfortable, talk with your doctor about what approach would be better for faster recovery. If your child’s cold symptoms do not improve or get worse, contact your doctor. A persistent cough may signal a more serious condition such as bronchitis or asthma.
Q. My child has taken an excessive amount of Cold-P Plus Suspension by mistake. What should I do?
Excess intake of Cold-P Plus Suspension can put your child at risk of developing serious side effects like seizures, psychiatric symptoms, urinary retention, shaking of hands, blurred vision, severe abdominal pain, and rapid heart rate. In such cases, call your child’s doctor right away.
Q. Can other medicines be given at the same time as Cold-P Plus Suspension?
Cold-P Plus Suspension can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Cold-P Plus Suspension. Also, check with your child’s doctor before giving any medicine to your child.
Q. My child has a seizure disorder. Is it safe to give Cold-P Plus Suspension to my child?
Avoid giving Cold-P Plus Suspension if your child is suffering from a seizure disorder. Apart from this, Cold-P Plus Suspension should also be avoided in children with cardiovascular disease (hypertension, heart disease), diabetes mellitus, gastrointestinal obstruction, increased intraocular pressure, urinary obstruction, or thyroid dysfunction. Always inform the doctor about your child’s medical history and consult your child’s doctor before giving Cold-P Plus Suspension for any medical condition.
