Manufacturer: Wockhardt Ltd
Salt Composition : Paracetamol, Phenylpropanolamine, Chlorpheniramine Maleate
Coldwok Tablet may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor. It is usually best taken with food otherwise it may upset your stomach. Do not take more or use it for longer than recommended.Side effects are rare if this medicine is used correctly but this medicine may cause stomach pain, nausea, and vomiting in some people. Consult your doctor if any of these side effects bother you or do not go away.This medicine is widely prescribed and considered safe but is not suitable for everybody. Before taking it, let your doctor know if you have liver or kidney problems or are using blood-thinning medicines. It may affect the dose or suitability of this medicine. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
Coldwok Tablet is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever.Phenylpropanolamine belongs to a class of medications called nasal decongestants. It stimulates receptors on blood vessels in the nose and sinuses leading to its constriction and reduction in blood flow thereby relieving congestion.Coldwok Tablet is an antiallergic medication. When your body is exposed to an allergen (pollen, animal dander, house dust etc.), it produces a chemical called histamine. This causes watery eyes, runny or blocked nose, sneezing, skin rashes, itching etc. Coldwok Tablet works by blocking the action of histamine, thereby relieving these symptoms.
It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.The drug was shown to be rapidly absorbed with a mean tmaxof 1.47 ± 0.49 h and a mean elimination half-life of 4.0 ± 0.5 h. Phenylpropanolamine is predominantly excreted via the kidney with a mean renal clearance of 0.646 ± 0.089 liter/kg/h and 90.2 ± 1.7% excreted unchanged in the urine.Chlorpheniramine has a serum half-life of approximately 20 hours in adults, and elimination from the body is primarily by metabolism to monodesmethyl and didesmethyl compounds. The half-life is increased in the presence of renal dysfunction and decreased in children.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Coldwok
Nausea
Vomiting
Insomnia (difficulty in sleeping)
Headache
Constipation
Itching
Systemic hypertension (high blood pressure)
Palpitations
Dryness in mouth
Sleepiness
Drowsiness
Loss of appetite
Hypersensitivity to Coldwok Tablet is a contraindication. In addition, Coldwok Tablet should not be used if you have the following conditions:
Blockage of urinary bladder
Cannot empty bladder
Chronic difficulty having a bowel movement
Chronic obstructive lung disease
Closed angle glaucoma
Enlarged prostate
Glaucoma
Hepatic impairment
High blood pressure
Hypersensitivity
Coldwok Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Coldwok Tablet.
Information regarding the use of Coldwok Tablet during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
Paracetamol + Phenylpropanolamine + Chlorpheniramine Maleate is a combination of three medicines: Paracetamol , Phenylpropanolamine and Chlorpheniramine Maleate which relieve cold symptoms. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that cause pain and fever. Phenylpropanolamine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Chlorpheniramine Maleate is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing.
If you use other drugs or over the counter products at the same time, the effects of Coldwok Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Coldwok Tablet may interact with the following drugs and products:
Acebutolol
Alcohol
Antidepressants
Atropine
Bromocriptine
Debrisoquine
Diazepam
Doxepin
Ephedrine
Furazolidone
Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Coldwok Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Coldwok Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Paracetamol
Paracetamol should be taken with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
Do not take indigestion remedies (antacids) within 2 hours of taking Paracetamol.
Avoid consuming alcohol while taking this medicine as it can increase your risk of stomach problems.
Inform your doctor if you have liver disease as your dose may need to be adjusted.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
Phenylpropanolamine
Do not continue phenylpropanolamine for more than 7 days if your condition does not improve or if you have high fever.
Tell your doctor if you have high blood pressure, heart problems, liver or kidney disease, diabetes, prostate enlargement or visual problems due to increased pressure in the eyes (glaucoma).
Seek immediate medical attention and discontinue medication if you experience difficulty in breathing, sudden swelling or skin reactions, fits, rapid heartbeat or hallucinations.
Use with caution if you are a woman or an elderly patient. Woman may be at a higher risk of haemorrhagic stroke (bleeding in the brain).
Avoid driving or operating machinery if you feel dizzy or drowsy after taking phenylpropanolamine.
Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Do not take if allergic to phenylpropanolamine or any of its ingredients.
Chlorpheniramine Maleate
Avoid driving or operating dangerous machinery as it may decrease alertness.
Avoid consuming alcohol when taking the Chlorpheniramine Maleate, as it may cause excessive sleepiness or drowsiness.
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Coldwok Tablet may be taken with or without food, but it is better to take it at a fixed time.
Paracetamol
Q. What if I vomit after taking Paracetamol?
If you vomit in less than 30 minutes after having a dose of Paracetamol tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.
Q. When will I feel better after taking the Paracetamol?
Usually, you will start feeling better after about half an hour of taking a Paracetamol.
Q. How often can I take the Paracetamol?
You should only take four doses of Paracetamol in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take Paracetamol for more than 3 days without consulting a doctor first.
Q. Does Paracetamol make babies sleepy?
No, Paracetamol does not make babies sleepy. It is a pain-relieving medicine that is also used to control high fever.
Q. Is Paracetamol safe for children?
Paracetamol is considered safe for children only when used as directed by the doctor.
Q. Is Paracetamol an antibiotic?
No, Paracetamol is not an antibiotic. It works as a painkiller and fever-reducing medicine.
Q. Can I take Paracetamol and ibuprofen together?
Ibuprofen and Paracetamol are safe medicines, but both should not be used together. Consult your doctor if you are not sure.
Q. How long does a Paracetamol take to work?
Paracetamol takes around 30-45 min to start working and show its effects. It is advised to take this medicine for the duration suggested by the doctor. Consult your doctor if you experience any bothersome side effects.
Q. What are the serious side effects of taking an excess of the Paracetamol?
Overdose of Paracetamole may cause severe life-threatening liver injury. Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of a suspected overdose.
Phenylpropanolamine
Q. Is phenylpropanolamine the same as phenylephrine?
Phenylpropanolamine and phenylephrine are different drugs belonging to the same class of medications (nasal decongestants). Both are used to relieve blocked nose or sinuses caused by common cold and seasonal nasal allergies (hay fever)
Q. Does Phenylpropanolamine cause stroke?
Phenylpropanolamine has shown to increase the risk of hemorrhagic stroke (bleeding in the brain). Women are at a higher risk.
Q. Is Phenylpropanolamine a controlled substance?
Phenylpropanolamine is a controlled substance since it can be used for manufacturing of illegal drugs
Q. Is Phenylpropanolamine still on the market?
Phenylpropanolamine is banned in India due to increased risk of haemorrhagic stroke (bleeding in the brain) and is no longer marketed in India
Chlorpheniramine Maleate
Q. Does chlorpheniramine or chlorpheniramine maleate cause increase in blood pressure/ drowsy/non drowsy/sedating/get you high/keep you awake/sleepiness/make you tired/weight gain?
Chlorpheniramine causing these side effects is common or rare. Always consult your doctor, if you experience any of these side effects
Q. Is chlorpheniramine like Benadryl?
No, chlorpheniramine is different from Benadryl
Q. Is chlorpheniramine prescription?
Yes, it is available with doctor’s prescription only
Q. Can I take chlorpheniramine or chlorpheniramine maleate with Panadol/ cetirizine /Zyrtec/ Allegra/ warfarin/ diphenhydramine/ ibuprofen/Claritin/guaifenesin/Benadryl?
Yes, but taking other medicines may alter the effects of chlorpheniramine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required
Q. Does chlorpheniramine contain aspirin?
No, it does not contain aspirin in it. Chlorpheniramine is a different drug than aspirin.
