Colicraft Forte 2MIU Injection (1ml)


Colicraft Forte 2MIU Injection is given under the supervision of a healthcare professional. You should not self-administer this medicine at home. The dose and duration will be decided by your doctor based on the severity and type of infection you have. Get the injection regularly for as long as your doctor has prescribed to get maximum benefits.



Basic Information

Mechanism Of Action

Colistin displaces the divalent cations of calcium (Ca2+) and magnesium (Mg2+) in a competitively way, impairing the LPS three-dimensional structure. Colistin then inserts its hydrophobic terminal acyl fat chain, causing an expansion of the external outer membrane (OM) monolayer.02

Pharmacokinets

Colistin is an old molecule that is frequently used as last-line treatment for infections caused by multidrug-resistant Gram-negative bacteria. Colistin is a decapeptide administered either as a prodrug, colistin methanesulfonate (CMS), when used intravenously, or as colistin sulfate when used orally

Side Effects

Nausea

Diarrhea

Vomiting

Kidney damage

Contra Indications

Slurred speech.

Spinning sensation (vertigo)

Seizures.

Severe allergic reaction (anaphylaxis)


Pregnancy Related Information

Colicraft Forte 2MIU Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

Consuming alcohol with Colicraft Forte 2MIU Injection does not cause any harmful side effects.


Breast Feeding Related Information

Colicraft Forte 2MIU Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Colistin Sulphate is used in the treatment of severe bacterial infections. It is used to treat certain types of serious infections which are not responding to other antibiotics. Colistin Sulphate is an antibiotic. It kills bacteria by destroying the bacterial cell membrane

Interactions

amphotericin B deoxycholate.

atracurium.

bacitracin.

cholera vaccine.

cidofovir.

cisatracurium.

neomycin PO.

onabotulinumtoxinA.


Typical Dosage

Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

It is given by a drip or by injection into the vein under the supervision of a doctor.

It may also be used to kill the natural bacteria that are present in the stomach before surgery on the stomach.

Do not use it for any other types of bacterial infections.

Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.

Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.


How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. What should I tell my doctor before taking Colicraft Forte 2MIU Injection?

Before taking Colicraft Forte 2MIU Injection, you must tell your doctor if you have or ever had any problems related to your kidneys or liver. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Q. Who should not use Colicraft Forte 2MIU Injection?

Use of Colicraft Forte 2MIU Injection should be avoided in patients who are allergic to Colicraft Forte 2MIU Injection or any of its components. However, if you are not aware of any allergy or if you are using Colicraft Forte 2MIU Injection for the first time, consult your doctor.

Q. Can I take Colicraft Forte 2MIU Injection in pregnancy?

Enough evidence is not available to provide clarity on the use of Colicraft Forte 2MIU Injection in pregnancy. However, if you are pregnant or planning to conceive, consult your doctor before taking Colicraft Forte 2MIU Injection. You may take it only if prescribed by your doctor.

Q. Is Colicraft Forte 2MIU Injection safe?

Colicraft Forte 2MIU Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.