Combihale FF CFC Free 250 Inhaler (120MDI)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Your doctor will tell you how often you need to use your inhaler. It’s important that you take the lowest dose needed to effectively control your asthma. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your asthma and COPD may get worse. It should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler (reliever). To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it Does not work as well.


Basic Information

Mechanism Of Action

Combihale FF CFC Free 250 Inhaler is a combination of two medicines: Formoterol and Fluticasone Propionate. Formoterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid.

Pharmacokinets

Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers.

For inhaled fluticasone propionate (FP), oral bioavailability is negligible due both to low absorption from the gastrointestinal tract and high hepatic first-pass metabolism [6]. Therefore, any systemic effects of this drug arise from lung absorption.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Combihale FF

Headache

Cough

Upper respiratory tract infection

Nasopharyngitis (inflammation of the throat and nasal passages)

Sinus inflammation

Stomach discomfort

Fungal infection of oropharynx

Tremors

Palpitations

Voice change


Contra Indications

thyrotoxicosis.

diabetes.

low amount of potassium in the blood.

high blood pressure.

diminished blood flow through arteries of the heart.

prolonged QT interval on EKG.

abnormal heart rhythm.

abnormal EKG with QT changes from birth.

Pregnancy Related Information

Combihale FF CFC Free 250 Inhaler may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Combihale FF CFC Free 250 Inhaler.


Breast Feeding Related Information

Combihale FF CFC Free 250 Inhaler is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Combihale FF CFC Free 250 Inhaler is used in the treatment of asthma (wheezing and shortness of breath) and chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked). It relaxes the muscles of the air passages and making it easier to breathe.

Interactions

Drug-Drug interactions: Combihale FF 250 Inhaler may interact with anti-fungal (ketoconazole) and HIV medications (ritonavir). Inform your doctor if you are taking any other steroid medicines. Drug-Food Interactions: No interactions found.


Typical Dosage

While you are breathing in from mouth, press down on the inhaler one time to release the medication and hold your breath for 10 seconds.

Storage Requirements

Store below 30°C


Expert Advice

Combihale FF CFC Free 250 Inhaler is a combination of two medicines that opens the airways and makes it easier to breathe.

This medicine is for inhalation only. The tablet should not be swallowed.

It should be taken at the same time each day.

It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.

Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.

Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.

Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.

Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Combihale FF CFC Free 250 Inhaler can lower blood potassium level.

Only miniscule amounts of Combihale FF CFC Free 250 Inhaler may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.


How To Use

Check the label for directions before use. Shake the inhaler. While you are breathing in from mouth, press down on the inhaler one time to release the medication and hold your breath for 10 seconds. Repeat until you have inhaled the number of puffs as suggested by the doctor.Afterwards, rinse your mouth thoroughly with water and spit it out.