Manufacturer: Zydus Cadila
Salt Composition : Levosalbutamol(50mcg), Ipratropium(20mcg)
Packet of 200Mdi Inhaler
(Inclusive of all taxes)
Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your COPD may get worse. This medicine should not be used to relieve sudden shortness of breath. If sudden shortness of breath occurs, use your rescue inhaler. To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it Does not work as well.
Ipratropium is an acetylcholine antagonist via blockade of muscarinic cholinergic receptors. Blocking cholinergic receptors decreases the production of cyclic guanosine monophosphate (cGMP). This decrease in the lung airways will lead to decreased contraction of the smooth muscles.
Ipratropium bromide is poorly absorbed from the gastrointestinal tract. The bioavailability of the drug by inhalation is 0.03–6.9%, and about 90% of the inhaled dose is swallowed. Following the inhalation of 2 mg, the bioavailability was found to be 6.9%. The bioavailability of the intranasal dose is less than 20%.
Dryness in mouth
Breathlessness
Cough
Tremors
Headache
Palpitations
Muscle cramp
Previous severe allergic reaction symptoms upon using ipratropium or atropine and its other derivatives, such as angioedema, urticaria, severe shortness of breath, oropharyngeal edema, and ultimately anaphylaxis is a contraindication to ipratropium use
Combimist-L CFC Free Inhaler may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Combimist-L CFC Free Inhaler may cause excessive drowsiness with alcohol.
Combimist-L CFC Free Inhaler is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
IPRATROPIUM+LEVOSALBUTAMOL belongs to the class of medications called bronchodilators used to treat or prevent symptoms of chronic obstructive pulmonary disease (COPD), such as shortness of breath, coughing, and wheezing (whistling sound while breathing).
Drug-Drug Interaction: IPRATROPIUM BROMIDE+LEVOSALBUTAMOL may interact with bronchodilators (salmeterol, albuterol, vilanterol, formoterol, tiotropium), steroids (budesonide, prednisone), water pills (furosemide), anti-sickness drug (ondansetron), heart-related medicines (atropine).
Shake the inhaler. While you are breathing in from mouth, press down on the inhaler one time to release the medication and hold your breath for 10 seconds. Repeat until you have inhaled the number of puffs as suggested by the doctor.Afterwards, rinse your mouth thoroughly with water and spit it out.
Store below 30°C
If you miss a dose of Combimist-L CFC Free Inhaler, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Combimist-L CFC Free Inhaler is a combination of two medicines that makes breathing easier for patients with chronic obstructive pulmonary disease (COPD).
This medicine is for inhalation only. The tablet should not be swallowed.
It should be taken at the same time each day.
It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Combimist-L CFC Free Inhaler can lower blood potassium level.
Only miniscule amounts of Combimist-L CFC Free Inhaler may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.
Check the label for directions before use. Shake the inhaler. While you are breathing in from mouth, press down on the inhaler one time to release the medication and hold your breath for 10 seconds. Repeat until you have inhaled the number of puffs as suggested by the doctor.Afterwards, rinse your mouth thoroughly with water and spit it out.
Q. Are there any medicines which I should avoid while taking Combimist-L CFC Free Inhaler?
It is not recommended to use Combimist-L CFC Free Inhaler along with other medicines, such as anticholinergic, beta-adrenergic agents, beta-blockers, diuretics, digoxin, MAO inhibitors or anti-depressants.
Q. Will Combimist-L CFC Free Inhaler be more effective if taken in higher doses?
No, taking a higher than the recommended dose of this medicine will not make it more effective, rather can lead to increased side effects. If the symptoms do not get relieved by the recommended doses, please consult the doctor for re-evaluation.
Q. Can the use of Combimist-L CFC Free Inhaler cause sleepiness or drowsiness?
Yes, Combimist-L CFC Free Inhaler may make you feel drowsy or sleepy. Avoid driving, operating machinery, working at heights, or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.
Q. Can the use of Combimist-L CFC Free Inhaler cause dry mouth?
Yes, the use of Combimist-L CFC Free Inhaler can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night.
