Combitaz (Injection)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

₹314.50

Vial of 1 Injection

(Inclusive of all taxes)


Combitaz Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.



Basic Information

Mechanism Of Action

Combitaz Injection is a combination of two medicines: Ceftazidime and Tazobactum. Ceftazidime is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria

Pharmacokinets

The pharmacokinetics of ceftazidime were characterized by a half life of 0-8 to 1-9 h in six patients with GFR above 90 ml/min/1-73 m2 body area while the half life was 3-2-3-7 h in three patients with GFR between 47 and 54 ml/min/1-73 m2 body area

Within 30 min of infusion, piperacillin/tazobactam achieves 16-85% of plasma concentrations in skin, muscle, lung, gallbladder, and intestinal mucosa. Plasma and tissue levels remain above the MIC90s of major pathogens for 2 h post administration

Side Effects

Nausea

Vomiting

Diarrhea

Stomach pain

Increased liver enzymes

Allergic reaction

Contra Indications

diarrhea from an infection with Clostridium difficile bacteria.

a decrease in the blood clotting protein prothrombin.

inflammation of the large intestine.

liver problems.

chronic kidney disease stage 3A (moderate)

chronic kidney disease stage 3B 

diarrhea from an infection with Clostridium difficile bacteria.

low amount of potassium in the blood.

increased risk of bleeding due to clotting disorder.

seizures.

a significant drop in a certain type of white blood cell called a neutrophil.


Pregnancy Related Information

Combitaz Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

Consuming alcohol with Combitaz Injection does not cause any harmful side effects.


Breast Feeding Related Information

Combitaz Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Indications

Combitaz Injection is a combination medicine. It is prescribed to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth and further spread of the infection.


Interactions

bazedoxifene/conjugated estrogens.

dienogest/estradiol valerate.

estradiol.

estropipate.

ethinylestradiol.

levonorgestrel oral/ethinylestradiol/ferrous bisglycinate.

probenecid.

sodium picosulfate/magnesium oxide/anhydrous citric acid.

colitis.

coagulation abnormalities.

renal dysfunction.

hemodialysis.

cystic fibrosis.

seizures.

sodium/potassium.

Typical Dosage

Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Combitaz Injection, please consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.

Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.

Diarrhea may occur as a side effect. Taking probiotics along with Combitaz Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.

Stop taking Combitaz Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.


How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. Can the use of Combitaz Injection cause diarrhea?

Yes, the use of Combitaz Injection can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.

Q. How long does Combitaz Injection takes to work?

Usually, Combitaz Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Q. What if I don't get better after using Combitaz Injection?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.