Comoflox 200mg Tablet (10'S)

Manufacturer: Lincoln Pharmaceuticals Ltd

Salt Composition : Ofloxacin(200mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

₹45.00

Strip of 10 Tablet

(Inclusive of all taxes)


Ofloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.


Ofloxacin is in a class of antibiotics called fluoroquinolones which works against bacteria that cause infections and stops the growth of the bacteria causing the infection and clears the infection. 


Before taking COMOFLOX 200MG inform your doctor if you have any allergic reactions, liver, kidney or heart problems. Inform your physician if you are pregnant or breastfeeding. It is not suitable for children and adolescents below 18 years of age.  The common side effects are nausea, stomach pain, diarrhoea or headache.



Basic Information

Mechanism Of Action

Ofloxacin is a quinolone antimicrobial agent. The mechanism of action of ofloxacin and other fluoroquinolone antimicrobials involves inhibition of bacterial topoisomerase IV and DNA gyrase (both of which are type II topoisomerases), enzymes required for DNA replication, transcription, repair and recombination.

Pharmacokinets

The pharmacokinetics of ofloxacin are characterised by almost complete bioavailability (95 to 100%), peak serum concentrations in the range of 2 to 3 mg/L after a 400mg oral dose and an average half-life of 5 to 8h.

Side Effects

Nausea

Stomach pain

Diarrhoea

Headache

Contra Indications

diarrhea from an infection with Clostridium difficile bacteria.

diabetes.

low blood sugar.

dehydration.

low amount of potassium in the blood.

a low seizure threshold.

a painful condition that affects the nerves in the legs and arms called peripheral neuropathy.


Pregnancy Related Information

There are limited studies available on COMOFLOX 200MG and it may cause harmful effects on the developing baby. Consult your doctor.


Product And Alcohol Interaction

Consumption of alcohol is not recommended while taking this COMOFLOX 200MG.


Breast Feeding Related Information

There are limited human data suggests that the COMOFLOX 200MG may pass into the breastmilk and harm the baby. Consult your doctor.


Indications

Tablets are indicated for the treatment of adults with mild to moderate infections (unless otherwise indicated) caused by susceptible strains of the designated microorganisms in the infections listed below.

Interactions

Some products that may interact with this drug include: "blood thinners" (such as acenocoumarol, warfarin), strontium. Many drugs besides ofloxacin may affect the heart rhythm (QT prolongation), including dofetilide, procainamide, amiodarone, quinidine, sotalol, among others. Ofloxacin is very similar to levofloxacin.

Typical Dosage

Do not crush or chew. Do not exceed the recommended dose.


Storage Requirements

Store below 20-25°C and keep out of reach of children.


Effects Of Missed Dosage

CONSULT A DOCTOR 

Effects Of Overdose

CONSULT A DOCTOR 

Expert Advice

CONSULT A DOCTOR 

How To Use

Always take COMOFLOX 200MG as instructed by your doctor. Swallow as whole and do not crush or chew. Do not exceed the recommended dose.


FAQs

Can I stop taking COMOFLOX 200MG when my symptoms are relieved?

No, do not stop taking and complete the full course of treatment even if you feel better.

Can the use of COMOFLOX 200MG cause diarrhea?

Yes. It may cause diarrhea, if you are experiencing severe diarrhea, consult your doctor for advice.

How long does COMOFLOX 200MG take to work?

Usually, it starts working soon after taking and it may take some days to act against the harmful bacteria.