Comptil 12.5mg Injection (1ml)

Manufacturer: Trends Pharma Pvt Ltd

Salt Composition : Prochlorperazine(12.5mg)


Comptil 12.5mg Injection is given by your doctor or nurse. The dose you are given will depend on your condition and how you respond to the medicine. You should take this medicine until your doctor tells you to stop. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.



Basic Information

Mechanism Of Action

As a first-generation antipsychotic, prochlorperazine mainly blocks D2 dopamine receptors in the brain. It can also block histaminergic, cholinergic, and noradrenergic receptors

Pharmacokinets

Plasma half-life (t1/2) of prochlorperazine was 6.8 +/- 0.7 h and 6.9 +/- 0.8 h for the 12.5 mg and 6.25 mg i.v. doses respectively. Apparent volume of distribution and plasma clearance were high and the kinetics did not appear to be dose-related

Side Effects

Drowsiness

Orthostatic hypotension (sudden lowering of blood pressure on standing)

Contra Indications

History of allergy to prochlorperazine or the phenothiazine drug class.

Concomitant use of CNS depressants (opioids, benzodiazepines, and barbiturates) leading to sedation.

Concomitant use of anticholinergic medications (scopolamine, atropine, etc.)

Pre-existing cardiac conduction abnormalities.


Pregnancy Related Information

Information regarding the use of Comptil 12.5mg Injection during pregnancy is not available. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Comptil 12.5mg Injection.


Breast Feeding Related Information

Comptil 12.5mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Occasional short-term use of Comptil 12.5mg Injection for the treatment of nausea and vomiting poses little risk to the breastfed infant.


Indications

Prochlorperazine is a first-generation antipsychotic. FDA indications include schizophrenia, schizoaffective, and other conditions presenting with symptoms of psychosis, as well as nausea and vomiting

Interactions

disopyramide.

ibutilide.

indapamide.

metrizamide.

pentamidine.

pimozide.

procainamide.

quinidine.


Typical Dosage

Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Overdose

Store below 30°C


Expert Advice

Comptil 12.5mg Injection is used for the prevention and treatment of nausea and vomiting.

It may also be used to treat dizziness associated with problems of the inner ear such as Meniere’s Syndrome.

It may cause sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.

To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

Avoid consuming alcohol when taking the Comptil 12.5mg Injection as it may cause excessive drowsiness.

It makes you more likely to get heatstroke. Avoid heavy exercising and drink plenty of fluids.

It can cause your skin to be more sensitive to sunlight. Avoid exposure to direct sunlight while having this medicine.


How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. How does Comptil 12.5mg Injection work?

Comptil 12.5mg Injection is used to treat mental disorders like schizophrenia. It is also used to treat and prevent nausea, and vomiting.It may be used to treat anxiety (short-term) in certain cases where other anti-anxiety drugs have been ineffective. It is also used to treat nausea, vomiting, dizziness or spinning sensations (vertigo) due to Meniere's disease.It belongs to a class of medication call phenothiazines. It acts on the central nervous system by blocking certain receptors thus producing an anti-psychotic and anti-vomiting effect

Q. Does Comptil 12.5mg Injection expire?

Yes, Comptil 12.5mg Injection does expire. Please check the expiry date written on the pack and it refers to the last day of that month. Do not use Comptil 12.5mg Injection after the expiry date.

Q. Is Comptil 12.5mg Injection available over the counter?

Comptil 12.5mg Injection is not available over the counter. It is available only on prescription from the doctor

Q. Is Comptil 12.5mg Injection safe to use?

Comptil 12.5mg Injection is safe to use for a prescribed duration in the dose as advised by a doctor.