Manufacturer: Emcure Pharmaceuticals Ltd
Salt Composition : Carmustine(100mg)
Consium 100mg Injection is generally administered by a doctor or a nurse. You should not self-administer this medicine at home. This dose and duration of the treatment will depend on what you are being treated and the severity of your condition. You should get the injection regularly for as long as the doctor has prescribed.
Carmustine causes cross-links in DNA and RNA, leading to the inhibition of DNA synthesis, RNA production and RNA translation (protein synthesis). Carmustine also binds to and modifies (carbamoylates) glutathione reductase. This leads to cell death. Hepatic and rapid with active metabolites
GLIADEL wafers have been shown to release carmustine in vivo over a period of approximately 5 days; when in continuous contact with interstitial fluid, wafers should degrade completely over a period of 6 to 8 weeks
Nausea
Vomiting
Headache
Fever
Rash
Constipation
Weakness
Confusion
Infection
Hair loss
Convulsion
Depression
Speech disorder
Brain swelling
Thrombophlebitis
Hemiplegia (paralysis of one side of the body)
Sleepiness
Hemiplegia (paralysis of one side of the body)
Pain
a bad infection.
acute leukemia.
anemia.
decreased blood platelets.
low levels of white blood cells.
low levels of a type of white blood cell called neutrophils.
bleeding.
a condition where there is formation of fibrous tissue in the lung called pulmonary fibrosis.
Consium 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Consium 100mg Injection. Please consult your doctor.
Consium 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
BiCNU (carmustine for injection) is indicated as palliative therapy as a single agent or in established combination therapy with other approved chemotherapeutic agents in the following: 1. Brain tumors—glioblastoma, brainstem glioma, medulloblastoma, astrocytoma, ependymoma, and metastatic brain tumors
pulmonary infiltrates/fibrosis.
infections.
myelosuppression.
renal dysfunction.
hepatic dysfunction.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Consium 100mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Consium 100mg Injection is given as an injection into the veins under the supervision of a doctor.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Consium 100mg Injection safe?
Consium 100mg Injection is safe if taken at prescribed dose and duration as advised by your doctor.
Q. Is Consium 100mg Injection a vesicant?
Consium 100mg Injection is classified under irritants amongst chemotherapy drugs. However when administered at high doses it can act as vesicant.
Q. Does Consium 100mg Injection inhibit DNA replication?
Yes, Consium 100mg Injection works by preventing DNA replication
