Contus Cough Tablet (10'S)

₹35.13

Strip of 10 Tablet

(Inclusive of all taxes)


Contus Cough Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.



Basic Information

Mechanism Of Action

Phenylephrine is an agonist of α1-adrenoceptors. Nasal decongestant action is mediated by activation of α1-adrenoceptors in the arterioles of the nasal mucosa. This causes vasoconstriction, which leads to decreased edema and increased drainage of the sinus cavities.

Chlorpheniramine helps control the symptoms of cold or allergies but will not treat the cause of the symptoms or speed recovery. Chlorpheniramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms

Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.


Pharmacokinets


Phenylephrine is readily and completely absorbed from the gastro-intestinal tract after oral administration.It is subject to extensive presystemic metabolism in the gut wall and therefore has a systemic bioavailability of approximately 40% relative to intravenous dosing.
Chlorpheniramine has a serum half-life of approximately 20 hours in adults, and elimination from the body is primarily by metabolism to monodesmethyl and didesmethyl compounds. The half-life is increased in the presence of renal dysfunction and decreased in children.
Dextromethorphan is rapidly absorbed from the gastrointestinal tract and converted into the active metabolite dextrorphan in the liver by the cytochrome P450 enzyme CYP2D6. The average dose necessary for effective antitussive therapy is between 10 and 45 mg, depending on the individu

Side Effects

Nausea

Vomiting

Loss of appetite

Headache

Contra Indications

Contraindications : MAO inhibitor use w/in 14 days, Urinary retention, CAD, Uncontrolled or severe HTN. Caution if HTN, arrhythmias, cardiovascular disease, diabetes mellitus, angle-closure glaucoma, hyperthyroidism, renal impairment, PKU (phenylalanine-containing forms),

overactive thyroid gland.

closed angle glaucoma.

high blood pressure.

stenosing peptic ulcer.

blockage of the stomach or intestine.

blockage of the urinary bladder.

enlarged prostate.

an inability to completely empty the bladder.

Asthma, emphysema, tobacco smoking. Dextromethorphan is contraindicated in the treatment of chronic cough, especially when associated with excessive bronchial secretion.

Hepatic disease.

Children, infants

Pregnancy.

Breast-feeding.

Driving or operating machinery.

MAOI therapy.

Geriatric.


Pregnancy Related Information

Contus Cough Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

Caution is advised when consuming alcohol with Contus Cough Tablet. Please consult your doctor.


Breast Feeding Related Information

Contus Cough Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

The FDA-approved indication for intravenous (IV) phenylephrine hydrochloride is for increasing blood pressure in adults with clinically significant hypotension resulting primarily from vasodilation in such settings as septic shock or anesthesia

This medication is an antihistamine, prescribed for allergic conditions such as itchy and watery eyes, sneezing, runny nose, hay fever and common cold. It may also be used to relieve the itching from insect bites and bee stings.

Dextromethorphan is used to temporarily relieve cough caused by the common cold, the flu, or other conditions. Dextromethorphan will relieve a cough but will not treat the cause of the cough or speed recovery. Dextromethorphan is in a class of medications called antitussives


Interactions

The FDA-approved indication for intravenous (IV) phenylephrine hydrochloride is for increasing blood pressure in adults with clinically significant hypotension resulting primarily from vasodilation in such settings as septic shock or anesthesia

eluxadoline.

idelalisib.

isocarboxazid.

ivacaftor.

sodium oxybate.

tranylcypromine

isocarboxazid.

phenelzine.

procarbazine.

rasagiline.

safinamide.

selegiline.

tranylcypromine.

Typical Dosage

Do not chew, crush or break it. Contus Cough Tablet may be taken with or without food, but it is better to take it at a fixed time.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Contus Cough Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Contus Cough Tablet helps in the treatment of dry cough.

It is usually taken only for a short time until the symptoms clear up.

Measure the syrup with a special dose-measuring spoon or cup, not a regular table spoon.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.

Stop taking this medicine and inform your doctor if your cough persists for more than 1 week, tends to recur, or is accompanied by a fever, rash or persistent headache.


How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Contus Cough Tablet may be taken with or without food, but it is better to take it at a fixed time.


FAQs

Q. Can the use of Contus Cough Tablet cause sleepiness or drowsiness?

Yes, Contus Cough Tablet may make you feel drowsy or may cause you to fall asleep during your daily activities. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.

Q. Can I breastfeed while taking Contus Cough Tablet?

No, it is not advisable to breastfeed while using Contus Cough Tablet. This medicine contains Chlorpheniramine, an antihistamine, which can pass into the breast milk and may harm the baby. Inform your doctor that you are breastfeeding if you are advised to take this medicine.

Q. Will Contus Cough Tablet be more effective if taken in more than recommended dose?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. What are the instructions for storage and disposal of Contus Cough Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.