Corparin 40mg Injection

Manufacturer: Corona Remedies Pvt Ltd

Salt Composition : Enoxaparin(40mg)


Corparin 40 Injection is injected under the skin by a doctor or nurse. It should not be injected into a muscle. The dose and length of treatment are based on your medical condition, your response to the medicine, and what you are being treated for. It may also be based on your age and weight. It is important to keep using this medicine even if you do not notice any symptoms because it is preventing future harm. If you stop taking it, you could get a blood clot. While taking this medicine you should avoid doing things that increase your risk of bleeding or injury.



Basic Information

Mechanism Of Action

It binds to and potentiates antithrombin III, a serine protease inhibitor, to form a complex that irreversibly inactivates factor Xa. [4] Enoxaparin has less activity against factor IIa (thrombin) compared to unfractionated heparin.

Pharmacokinets

Enoxaparin is a type of low molecular weight heparin (LMWHs) with a mean molecular weight of 4000 to 5000. It has an immediate onset of action when given in the intravenous form. It binds to and potentiates antithrombin III, a serine protease inhibitor, to form a complex that irreversibly inactivates factor Xa.

Side Effects

Bleeding

Headache

Low blood platelets

Increased liver enzymes

Contra Indications

Known hypersensitivity to enoxaparin (urticaria, anaphylactic reactions) or any heparin products.

Active major bleeding such as gastrointestinal bleed.

History of heparin-induced thrombocytopenia within the past 100 days.

Active gastric or duodenal ulcers.

Hemorrhagic cerebrovascular accident

Pregnancy Related Information

Corparin 40 Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Corparin 40 Injection. Please consult your doctor.


Breast Feeding Related Information

Corparin 40 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Corparin 40 Injection is released in small amounts in the breast milk and amounts reaching the baby are also small, which would not be expected to cause any harmful effects to the baby.


Indications

Acute coronary syndromes such as ST-elevation myocardial infarction, Non-ST elevation myocardial infarction, and unstable angina.

Deep venous thrombosis (DVT) treatment.

Deep venous thrombosis (DVT) prophylaxis.

Treatment for pulmonary embolism (PE)

Venous thromboembolism secondary to malignancy

Interactions

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen, or naproxen. ...

Platelet inhibitors, such as clopidogrel, prasugrel, ticagrelor, or dipyridamole. ...

Herbal supplements, such as ginkgo biloba, fish oil, garlic, ginseng, and ginger.


Typical Dosage

 You or your care giver may be taught on how to use this device at home.


Storage Requirements

STORE BELOW 30 DEGREES C. 

Effects Of Missed Dosage

If you miss a dose of Corparin 40 Injection, please consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

You have been prescribed Corparin 40 Injection for the treatment and prevention of blood clots.

Corparin 40 Injection increases your risk of bleeding. Be careful while shaving, using sharp objects or cutting fingernails or toenails.

Inform your doctor if you are also taking other medicines that increase the bleeding risk like aspirin and NSAIDs.

Inform your doctor if there is bleeding from gums, nose or wounds that lasts more than 15 minutes or if blood appears in your urine, stool or vomit.

Do not stop taking the medication suddenly without talking to your doctor.

How To Use

Your doctor or nurse will use this device to give medicine. You or your care giver may be taught on how to use this device at home.


FAQs

Q. How do you administer Corparin 40 Injection?

Corparin 40 Injection is a medicine which is injected beneath the skin. Fix the dose of the medicine and pinch the skin of your stomach between your finger and thumb to make a fold. After having cleaned the area, hold the syringe like a pencil and insert the full length of the needle into the skin fold. Inject the medicine and discard the syringe as instructed by your prescribing physician. Follow the instructions given by the healthcare provider strictly. Contact your doctor in case of any doubt or any reactions associated with the medicine.

Q. What are the conditions where I should be cautious before taking Corparin 40 Injection?

You must give a proper history to your doctor before you start taking Corparin 40 Injection. Inform your doctor if you have a heart valve fitted or have gastric ulcer, high blood pressure, diabetes, or kidney problems. You should also let your doctor know if you ever had a reaction to heparin or had a recent stroke, brain or spinal surgery. The chances of side effects and complications increase in presence of these conditions. Consult with your doctor and follow the instructions strictly.

Q. How to store Corparin 40 Injection injections?

Store Corparin 40 Injection injections at 25°C and do not freeze them. The multiple-dose vials should not be stored for more than 28 days after the first use. Discard the injection if you notice any particulate matter or abnormal color in the solution or any damage in the syringe. Read the medicine package leaflet before using this medication and ask the pharmacist in case of any doubt.

Q. Can Corparin 40 Injection be used in heart attack?

Yes, Corparin 40 Injection is used in the treatment of chest pain and heart attack once the standard treatment has been provided to the patient. It is given along with another blood thinner like aspirin. Being a blood-thinning agent, it prevents the blood from clotting and prevents any further episodes and complications.