Manufacturer: Macleods Pharmaceuticals Pvt Ltd
Salt Composition : Cycloserine(250mg)
Coxerin Capsule may be taken with or without food. You should take it regularly at evenly spaced intervals as per the dose and schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. You should always complete a full course of this antibiotic as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive and the infection may come back. Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. Pregnant and breastfeeding mothers should not take this medicine. Your doctor may get regular blood and urine tests while undergoing treatment with this medicine.
Cycloserine works as an antibiotic by inhibiting cell-wall biosynthesis in bacteria. As a cyclic analogue of D-alanine, cycloserine acts against two crucial enzymes important in the cytosolic stages of peptidoglycan synthesis: alanine racemase (Alr) and D-alanine:D-alanine ligase (Ddl).
In healthy Chinese volunteers, Zhou et al. have shown that cycloserine follows linear pharmacokinetics, with average Cmax values of 19.4, 42.9, and 84.8 mg/liter after single doses of 250, 500, and 750 mg, respectively.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Coxerin
Memory loss
Confusion
Insomnia (difficulty in sleeping)
Retching
Difficulty in speaking
Dizziness
Headache
Convulsion
Anemia (low number of red blood cells)
Stomach pain
Acne-like rash
Paresthesia (tingling or pricking sensation)
Numbness
Irritation
Vertigo
Inflammation of vein
Suicidal behaviors
Abnormal behavior
Sleepiness
inadequate folic acid.
inadequate vitamin B12.
megaloblastic anemia.
sideroblastic anemia.
psychotic disorder.
alcoholism.
depression.
decreased kidney function.
Coxerin Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consuming alcohol while taking Coxerin Capsule may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Coxerin Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Cycloserine belongs to the family of medicines called antibiotics. It is used to treat tuberculosis (TB). When cycloserine is used for TB, it is given with other medicines for TB. Cycloserine may also be used for other conditions as determined by your doctor.
Cycloserine has no listed severe interactions with other drugs. Cycloserine has no listed serious interactions with other drugs.
Coxerin Capsule may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Coxerin Capsule, consult your doctor.
Consult a doctor before taking any medicines.
Coxerin Capsule is used in combination with other medicines for the treatment of tuberculosis.
Take it at the same time every day to help you remember to take it.
Coxerin Capsule may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid drinking alcohol while taking Coxerin Capsule as this may worsen the side effects.
During treatment, you will need to have regular blood tests to monitor your kidney and liver function, blood cell counts and the amount of medicine in your blood.
Stop taking Coxerin Capsule and inform your doctor if you experience skin rashes, headaches, tremor, fits, problems with speech or movement, depression, or other changes in mood, thoughts or behavior.
Do not stop taking this medicine until your doctor tells you to.
Take this medicine in the dose and duration as advised by your doctor. Coxerin Capsule may be taken with or without food, but it is better to take it at a fixed time.
