Manufacturer: Marc Laboratories Pvt Ltd
Salt Composition : Rifampicin(100mg), Isoniazid(50mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Coxwin Kid 100 mg/50 mg Tablet is a prescription medicine and it is to be taken as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.
Coxwin Kid 100 mg/50 mg Tablet is a combination of two antibiotics: Rifampicin and Isoniazid, which treats tuberculosis (TB). Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Isoniazid prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.
Approximately 80% of rifampicin is transported in blood bound to plasma proteins, mainly albumin. Rifampicin is well distributed, although to a different degree, in the various tissues of the human body. Probably in the hepatocyte, rifampicin undergoes a process of desacetylation.The known mode of action of isoniazid (INH) is to inhibit bacterial cell wall synthesis following activation by the bacterial catalase–peroxidase enzyme KatG in Mycobacterium tuberculosis (Mtb).
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Coxwin Kid
Dark colored urine
Rash
Vomiting
Jaundice
Fever
Increased liver enzymes
Nausea
Peripheral neuropathy (tingling and numbness of feet and hand)
If you are suffering from any of the following diseases, you should not take Isoniazid + Rifampicin unless your doctor advises you to do so -
Liver Disease
Liver Cirrhosis
Jaundice
Kidney Disease
Heart Disease
Coxwin Kid 100 mg/50 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consuming alcohol while taking Coxwin Kid 100 mg/50 mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Coxwin Kid 100 mg/50 mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Use with caution
Below 9years: Contraindicated
Rifampin and Isoniazid is a prescription medicine used to treat the symptoms of Tuberculosis. Rifamate may be used alone or with other medications. Rifamate belongs to a class of drugs called Antitubercular Agents. It is not known if Rifamate is safe and effective in children younger than 15 years of age.
ISONIAZID+RIFAMPICIN may have interaction with anti-HIV (saquinavir, ritonavir), pain killer (acetaminophen, hydrocodone), anti-depressant (duloxetine, bupropion), calcium channel blocker (diltiazem), anti-TB (ethambutol, pyrazinamide), and vitamins (ergocalciferol, cholecalciferol).
Do not chew, crush or break it. Coxwin Kid 100 mg/50 mg Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Coxwin Kid 100 mg/50 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Coxwin Kid 100 mg/50 mg Tablet for the treatment of tuberculosis.
Finish the full course of the medication, even if you feel better. Stopping it early may make the infection come back.
Take it on an empty stomach, preferably at the same time everyday.
It may discolour your urine, sweat, saliva and tears a reddish-orange colour. This is normal and not harmful.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Avoid drinking alcohol while taking Coxwin Kid 100 mg/50 mg Tablet as this may increase the risk of side effects on the liver.
Use an alternative or additional contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Coxwin Kid 100 mg/50 mg Tablet as it may make hormonal contraceptives such as the pill less effective.
Do not take indigestion remedies (antacids) within at least two hours of taking Coxwin Kid 100 mg/50 mg Tablet.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Coxwin Kid 100 mg/50 mg Tablet is to be taken empty stomach.
Avoid Coxwin Kid 100 mg/50 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Q. What is Coxwin Kid 100 mg/50 mg Tablet?
Coxwin Kid 100 mg/50 mg Tablet is a combination of two medicines: Rifampicin and Isoniazid. It is used in the treatment of tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by tuberculosis bacteria to make essential proteins and reproduce. Isoniazid prevents the tuberculosis causing bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.
Q. What is the most important information I should know about the Coxwin Kid 100 mg/50 mg Tablet?
Take the proper course of drug that has been prescribed to you. Do not stop in between even if you begin to feel better. Avoid alcohol while taking this medicine as it increases the risk of damage to your liver during treatment. Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.
Q. What is the best time to take Coxwin Kid 100 mg/50 mg Tablet?
Take Coxwin Kid 100 mg/50 mg Tablet exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.
Q. Does Coxwin Kid 100 mg/50 mg Tablet cause change in urine color/turn urine orange?
Yes, Coxwin Kid 100 mg/50 mg Tablet can change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful.
Q. Does the use of Coxwin Kid 100 mg/50 mg Tablet make birth control pills ineffective?
Yes, Coxwin Kid 100 mg/50 mg Tablet can make birth control pills less effective. So, ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm and spermicide).
Q. What are the instructions for storage and disposal of Coxwin Kid 100 mg/50 mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
