Cresp 40mcg Injection


Cresp 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.



Basic Information

Mechanism Of Action

Darbepoetin alfa binds to the erythropoietin receptor on erythroid progenitor cells, stimulating RBC production and differentiation.


Pharmacokinets

The distinct molecular structure of darbepoetin alfa, in both its amino acid sequence and its carbohydrate content, results in a biologic profile with lower binding affinity, longer circulating half-life, and higher in vivo potency compared with the epoetins

Side Effects

High blood pressure

Rash

Injection site pain

Breathlessness

Cough

Peripheral edema

Procedural hypotension (low blood pressure)

Convulsion

Thromboembolism

Contra Indications

inadequate folic acid.

inadequate vitamin B12.

porphyria.

anemia from inadequate iron.

high blood pressure.

significant uncontrolled high blood pressure.

a heart attack.

a clot in the lung.


Pregnancy Related Information

Cresp 40 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Cresp 40 Injection. Please consult your doctor.


Breast Feeding Related Information

Cresp 40 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Aranesp is indicated for the treatment of anemia in patients with non-myeloid malignancies where anemia is due to the effect of concomitant myelosuppressive chemotherapy, and upon initiation, there is a minimum of two additional months of planned chemotherapy.


Interactions

belzutifan.

benazepril.

C1 esterase inhibitor (human)

captopril.

carfilzomib.

conestat alfa.

cyclosporine.

enalapril.

Typical Dosage

 Kindly do not self administer.


Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

If you miss a dose of Cresp 40 Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Cresp 40 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.

It is given as a single injection under your skin.

Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.

Stop taking Cresp 40 Injection and inform your doctor if you develop shortness of breath or skin rash.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. How long does it take for Cresp 40 Injection to start working?

You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Cresp 40 Injection. If you have any other concerns, consult your doctor.

Q. Is Cresp 40 Injection safe to use?

Cresp 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Cresp 40 Injection therapy. Follow all the directions strictly.

Q. Other than PRCA, can there be other reasons for not responding to Cresp 40 Injection?

You may not respond to Cresp 40 Injection if you have deficiencies of iron, folic acid or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation and bone marrow fibrosis. Therefore, consult our doctor regarding the same.

Q. Can Cresp 40 Injection be used in children?

Yes, Cresp 40 Injection is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Cresp 40 Injection and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.