Crevast Gold 20 Capsule (10'S)

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₹268.32

Strip of 10 Capsule

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Crevast Gold 20 Capsule is used for prevention of heart attack. It is a combination of medicines that prevents clot formation in the blood vessels. It also helps to reduce increased cholesterol and triglycerides levels. This medicine should be taken with food regularly at a fixed time each day. This medicine should not be stopped abruptly and taken strictly as advised by the doctor. Lifestyle changes like low-fat diet, exercise, and not smoking may help this medicine work better. This medicine increases your risk of bleeding, so it is important to be careful while shaving, cutting nails, and using sharp objects. Few common side effects of this medicine may include stomach pain, indigestion, diarrhea, and muscle pain.



Basic Information

Mechanism Of Action

He proved that aspirin and other non-steroid anti-inflammatory drugs (NSAIDs) inhibit the activity of the enzyme now called cyclooxygenase (COX) which leads to the formation of prostaglandins (PGs) that cause inflammation, swelling, pain and fever

Rosuvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body

The active metabolite of clopidogrel selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet P2Y12 receptor and the subsequent ADP- mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation


Pharmacokinets

Aspirin is rapidly absorbed in the upper gastrointestinal (GI) tract and results in a measurable inhibition of platelet function within 60 minutes. This antiplatelet effect is associated with prolongation of the bleeding time and inhibition of TXA2-dependent platelet aggregation

The oral bioavailability of rosuvastatin is 20%, which is comparable to atorvastatin, pravastatin and fluvastatin, and qualitatively higher than simvastatin and lovastatin. After a single oral dose the peak plasma concentration is reached at 5 hours

In the liver, approximately 15% of absorbed clopidogrel is metabolized by the cytochrome P450 (CYP) system to generate its active metabolite via a 2-step bioactivation process, whereas the rest 85% is hydrolyzed by carboxylesterase 1 (CES1) to an inactive carboxylic acid derivative.


Side Effects

Increased bleeding tendency

Abdominal pain

Indigestion

Bruise

Nosebleeds

Gastrointestinal bleeding

Weakness

Headache

Muscle pain

Diarrhea

Nausea

Contra Indications

systemic mastocytosis.

low vitamin K levels.

a type of joint disorder due to excess uric acid in the blood called gout.

anemia.

hemophilia.

a decrease in the blood clotting protein prothrombin.

blood clotting disorder - von Willebrand's disease.

decreased blood platelets.

untreated decreased level of thyroid hormones.

dehydration.

alcoholism.

a hemorrhage in the brain.

liver failure.

liver problems.

acute kidney failure.

bloody urine.

General Information. ...

Bleeding, GI bleeding, intracranial bleeding, peptic ulcer disease, surgery, trauma. ...

Hepatic disease. ...

Renal disease, renal failure, renal impairment. ...

Poor metabolizers. ...

Epidural anesthesia, labor, obstetric delivery, pregnancy, spinal anesthesia. ...

Breast-feeding. ...

Geriatric.

Pregnancy Related Information

Crevast Gold 20 Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Crevast Gold 20 Capsule.


Breast Feeding Related Information

Crevast Gold 20 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

Rosuvastatin is a statin medication used as a lipid-lowering agent. The FDA-approved indications are homozygous familial hypercholesterolemia, hyperlipidemia, mixed dyslipidemia, primary dysbetalipoproteinemia, hypertriglyceridemia, and prevention of cardiovascular disease

Aspirin is indicated for temporary relief of headache, pain and fever of colds, minor pain of arthritis, muscle pain, menstrual pain, and toothache

FDA-approved indications for clopidogrel include: Use during a percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) and stable ischemic heart disease.

Interactions

atazanavir.

clarithromycin.

colchicine.

cyclosporine.

eltrombopag.

fenofibrate.

fenofibrate micronized.

fenofibric acid.

Some products that may interact with this drug include: mifepristone, acetazolamide, "blood thinners" (such as warfarin, heparin), corticosteroids (such as prednisone), dichlorphenamide, methotrexate, valproic acid, herbal medications (such as ginkgo biloba).

Diabetes drug. In most cases, repaglinide should not be taken with clopidogrel. ...

Stomach acid drugs (proton pump inhibitors) ...

Nonsteroidal anti-inflammatory drugs (NSAIDs) ...

Blood thinners.

Drugs used to treat depression. ...

Salicylates (aspirin) ...

Opioids.

Typical Dosage

Crevast Gold 20 Capsule is to be taken with food.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Crevast Gold 20 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

You have been prescribed Crevast Gold 20 Capsule to lower your risk of heart attacks and stroke.

Take it with food to avoid an upset stomach.

It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.

Notify your doctor if you are more tired than usual, do not feel hungry, or if you have yellow eyes, skin.

Notify your doctor if you experience muscle symptoms (pain or weakness), particularly if you have fever, a sick feeling or dark urine.

Let your doctor know you are taking Crevast Gold 20 Capsule before undergoing any surgical procedure.

Let your doctor know if you are pregnant or planning for pregnancy.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Crevast Gold 20 Capsule is to be taken with food.


FAQs

Q. What are the instructions for the storage and disposal of Crevast Gold 20 Capsule?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Will I need to stop Crevast Gold 20 Capsule before surgery or dental procedure?

Crevast Gold 20 Capsule may increase the risk of bleeding during a surgery or dental procedure. Therefore, you may be asked by your doctor to stop taking Crevast Gold 20 Capsule. However, do not stop taking Crevast Gold 20 Capsule on your own.

Q. What are the lifestyle changes to adapt while taking Crevast Gold 20 Capsule?

Making lifestyle changes can boost your health while taking Crevast Gold 20 Capsule. Stop smoking, as smoking increases your risk of having a heart attack and stroke. If you are overweight or obese, try to lose weight. You should maintain a healthy diet by including fruits and vegetables in your meals. Regular exercise can make your heart strong and decrease your risk of heart attack.

Q. Which painkiller is safe while taking Crevast Gold 20 Capsule?

Paracetamol is safe to use while taking Crevast Gold 20 Capsule for relieving pain. Avoid the use of other painkillers while taking Crevast Gold 20 Capsule, as they may increase the risk of bleeding.

Q. Can the use of Crevast Gold 20 Capsule increase the risk of bleeding?

Yes, Crevast Gold 20 Capsule increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.