Manufacturer: Leeford Healthcare Ltd
Salt Composition : Clidinium(2.5mg), Chlordiazepoxide(5mg), Dicyclomine(10mg)
Cromide Forte 2.5 mg/5 mg/10 mg Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. It inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites.
Chlordiazepoxide binds to stereospecific benzodiazepine (BZD) binding sites on GABA receptor complexes at several sites within the central nervous system, including the limbic system and reticular formation. This results in an increased binding of the inhibitory neurotransmitter GABA to the GABA receptor.
Dicyclomine is used to treat a certain type of intestinal problem called irritable bowel syndrome. It helps to reduce the symptoms of stomach and intestinal cramping. This medication works by slowing the natural movements of the gut and by relaxing the muscles in the stomach and intestines.
Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. It inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites.
Chlordiazepoxide is a long-acting benzodiazepine drug. The half-life of Chlordiazepoxide is 5 – 30 hours but has an active benzodiazepine metabolite esmethyldiazepam), which has a half-life of 36 – 200 hours.
Dicyclomine is 79.5% eliminated in the urine and 8.4% in the feces. The mean plasma elimination half life is approximately 1.8 hours
Nausea
Constipation
Nervousness
Dryness in mouth
Difficulty in urination
Confusion
Sleepiness
Weakness
Dizziness
Blurred vision
Impaired coordination
overactive thyroid gland.
myasthenia gravis, a skeletal muscle disorder.
closed angle glaucoma.
high blood pressure.
coronary artery disease.
chronic heart failure.
a change in saliva secretion.
achalasia of esophagus, a condition that makes swallowing difficult.
Documented hypersensitivity, Acute alcohol intoxication, Myasthenia gravis, Narrow angle glaucoma, Severe respiratory depression, Depressed neuroses, psychotic reactions, IV use in shock, coma, depressed respiration, patients who recently received other respiratory depressants.
Hypersensitivity to dicyclomine or any anticholinergic drugs.
Closed-angle glaucoma.
Myasthenia gravis.
Hemorrhage with cardiovascular instability.
Paralytic ileus.
Breastfeeding.
Intestinal atony of elderly/debilitated patients.
Toxic megacolon.
Cromide Forte 2.5 mg/5 mg/10 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Cromide Forte 2.5 mg/5 mg/10 mg Tablet.
Cromide Forte 2.5 mg/5 mg/10 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
This medication is a combination of 2 drugs, clidinium and chlordiazepoxide. It is used along with other medications to help treat stomach/intestinal disorders (such as ulcers, irritable bowel syndrome, bowel infections). Clidinium helps to reduce the symptoms of stomach and intestinal cramping
Librium (chlordiazepoxide) is indicated for the management of anxiety disorders or for the short term relief of symptoms of anxiety, withdrawal" symptoms of acute alcoholism, and preoperative apprehension and anxiety.
Dicyclomine is indicated for the treatment of functional bowel disorder and irritable bowel syndrome.
arrhythmias.
autonomic neuropathy.
GI obstruction.
glaucoma.
obstructive uropathy.
tardive dyskinesia.
infectious diarrhea.
psychoses.
acute alcohol intoxication.
closed-angle glaucoma.
drug dependence.
renal/liver disease.
respiratory depression.
seizures.
prolonged hypotension.
depression.
autonomic neuropathy.
GI obstruction.
glaucoma.
obstructive uropathy.
tardive dyskinesia.
myasthenia gravis.
infectious diarrhea.
CV acute hemorrhage.
Do not chew, crush or break it. Cromide Forte 2.5 mg/5 mg/10 mg Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Cromide Forte 2.5 mg/5 mg/10 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Cromide Forte 2.5 mg/5 mg/10 mg Tablet is prescribed to give relief from the symptoms of irritable bowel syndrome.
If you are due to have an operation or any dental treatment, please tell the doctor carrying out the treatment that you are taking Cromide Forte 2.5 mg/5 mg/10 mg Tablet. This is because Cromide Forte 2.5 mg/5 mg/10 mg Tablet increases the effects of some anesthetics.
Inform your doctor if you have an enlarged prostate gland, glaucoma, or trouble passing urine.
If you are 65 or older, use Cromide Forte 2.5 mg/5 mg/10 mg Tablet with care. You could have more side effects.
If you develop any new symptoms, or if your symptoms get worse, make an appointment to see your doctor for further advice.
Cromide Forte 2.5 mg/5 mg/10 mg Tablet is prescribed to give relief from the symptoms of irritable bowel syndrome.
If you are due to have an operation or any dental treatment, please tell the doctor carrying out the treatment that you are taking Cromide Forte 2.5 mg/5 mg/10 mg Tablet. This is because Cromide Forte 2.5 mg/5 mg/10 mg Tablet increases the effects of some anesthetics.
Inform your doctor if you have an enlarged prostate gland, glaucoma, or trouble passing urine.
If you are 65 or older, use Cromide Forte 2.5 mg/5 mg/10 mg Tablet with care. You could have more side effects.
If you develop any new symptoms, or if your symptoms get worse, make an appointment to see your doctor for further advice.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cromide Forte 2.5 mg/5 mg/10 mg Tablet is to be taken empty stomach.
Q. Is it safe to use Cromide Forte 2.5 mg/5 mg/10 mg Tablet?
Cromide Forte 2.5 mg/5 mg/10 mg Tablet is safe for most of the patients when taken as per the doctor's advice. However, in some patients it may cause common side effects like nausea, constipation, nervousness, dryness in the mouth, difficulty in urination, confusion, sleepiness, weakness, dizziness, blurred vision, impaired coordination and other uncommon or rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.
Q. Can the use of Cromide Forte 2.5 mg/5 mg/10 mg Tablet cause nausea and vomiting?
Yes, the use of Cromide Forte 2.5 mg/5 mg/10 mg Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Q. Can the use of Cromide Forte 2.5 mg/5 mg/10 mg Tablet cause dryness in mouth?
Yes, the use of Cromide Forte 2.5 mg/5 mg/10 mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.
Q. Can the use of Cromide Forte 2.5 mg/5 mg/10 mg Tablet cause dizziness?
Yes, the use of Cromide Forte 2.5 mg/5 mg/10 mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better.
