Manufacturer: Glaxo SmithKline Pharmaceuticals Ltd
Salt Composition : Pyrimethamine(25mg), Sulphadoxine(500mg)
Croydoxin FM 25 mg/500 mg Tablet is a prescription medicine. It is to be taken with food and take it at a fixed time regularly. Take the medicine in the dose and duration advised by your doctor. Do not consume more than the recommended dose, as this may have harmful effects on your body. A missed dose should be taken as soon as you remember. The course of the treatment should be completed for better efficacy.Some common side effects of this medicine are headaches, diarrhea, nausea, vomiting, weakness, indigestion, etc. You may also feel dizzy, thus it is advised not to drive or operate machinery. To overcome dizziness you should drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately.
Croydoxin FM 25 mg/500 mg Tablet is a combination of two medicines: Pyrimethamine and Sulphadoxine which treat malaria. Pyrimethamine is an antiparasitic medicine which works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite.
The pharmacokinetics of pyrimethamine have been studied in infants and adults. Pyrimethamine is metabolized in the liver. Its pharmacokinetics are not altered by renal insufficiency, but are affected by concomitantly administered drugs (e.g., phenobarbital).Sulfadoxine is available (combined with pyrimethamine) in both oral and intramuscular forms. It is rapidly and extensively absorbed from the gut. Sulfadoxine is about 94% bound to plasma proteins.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Croydoxin FM
Nausea
Vomiting
Diarrhea
Fatigue
Feeling of fullness
Dizziness
Headache
Mouth sore
Skin rash
Hypersensitivity to Croydoxin Fm Tablet is a contraindication. In addition, Croydoxin Fm Tablet should not be used if you have the following conditions:
Alcoholism
Allergic reactions
Blood dyscrasias
Bone marrow problems
Breastfeeding
Depression
Fits
Infants less than 2 months of age
Kidney or liver problems
Megaloblastic anemia
Croydoxin FM 25 mg/500 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Croydoxin FM 25 mg/500 mg Tablet. Please consult your doctor.
Croydoxin FM 25 mg/500 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Sulfadoxine and Pyrimethamine is indicated for the treatment of acute, uncomplicated P. falciparum malaria for those patients in whom chloroquine resistance is suspected.
If you use other drugs or over the counter products at the same time, the effects of Croydoxin Fm Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Croydoxin Fm Tablet may interact with the following drugs and products:
Leucovorin
Sulfonamides
Trimethoprim
Do not chew, crush or break it. Croydoxin FM 25 mg/500 mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Croydoxin FM 25 mg/500 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Croydoxin FM 25 mg/500 mg Tablet must be taken with food at the same time every day.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
It is advisable to drink plenty of fluids and a healthy diet while taking the medicine.
It may cause dizziness. Do not drive or do anything that requires mental focus until you know how medicine affects you.
Avoid consuming alcohol while taking medication as it may cause increased side effects.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Croydoxin FM 25 mg/500 mg Tablet is to be taken with food.
Q. What if I don't get better after using Croydoxin FM 25 mg/500 mg Tablet?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Q. Can I stop taking Croydoxin FM 25 mg/500 mg Tablet when I feel better?
No, do not stop taking Croydoxin FM 25 mg/500 mg Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
Q. What if I miss my dose?
Take Croydoxin FM 25 mg/500 mg Tablet as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.
