Manufacturer: Colinz Laboratories Ltd
Salt Composition : Domperidone, Ranitidine
Strip of 10 Tablet
(Inclusive of all taxes)
Cyclotab Tablet is a combination of two medicines. It is to be taken in the dose and duration advised by your doctor. In case you have missed a dose, take it as soon as you remember. Finish the full course of treatment even if you feel better. A high dose or overdose may have harmful effects on the body.
This medicine is generally well tolerated by patients. However, it may cause diarrhea, sleepiness, tiredness, headache, confusion, muscle pain in some people. Before taking the medicine always consult your doctor if you are pregnant, breastfeeding, or if you are suffering from any severe stomach, liver, kidney disease, or any known disease.
Ranitidine is a competitive inhibitor of histamine H2-receptors. The reversible inhibition of H2-receptors in gastric parietal cells results in a reduction in both gastric acid volume and concentration
The DA2-receptor antagonist domperidone antagonizes the inhibitory effect of dopamine, resulting in stimulation of gastric muscle contraction. This provides a mechanism for the gastrokinetic effect of domperidone.
The pharmacokinetics of ranitidine has been described previously[9-11]. After oral administration 50% of ranitidine is absorbed, resulting in the peak serum concentration of 2 ± 3 h after dosing, followed by elimination with a half-life of 2.5 ± 3 h.
The absorption of domperidone was very rapid, with mean peak plasma concentration (Cmax) values of 18.8, 15.0, and 20.7 ng/mL attained at 0.9, 1.2, and 0.6 hours after the administration of base tablet, maleate tablet, and solution, respectively. The mean elimination half-life (t1/2) ranged from 12.6 to 16.0 hours.
Diarrhea
Sleepiness
Tiredness
Headache
Confusion
Muscle pain
General Information. ...
H2-blocker hypersensitivity. ...
Gastric cancer. ...
Infection. ...
Hepatic disease. ...
Renal disease, renal failure, renal impairment. ...
Children, infants, neonates, premature neonates. ...
Pregnancy.
with conditions where cardiac conduction is, or could be, impaired.
with underlying cardiac diseases such as congestive heart failure.
receiving other medications known to prolong QT interval or potent CYP3A4 inhibitors.
with severe hepatic impairment.
Cyclotab Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Cyclotab Tablet.
Cyclotab Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Benign gastric ulcer disease, short-term, and maintenance.
Duodenal ulcer disease, short-term, and maintenance.
Erosive esophagitis.
Hypersecretory conditions (e.g., Zollinger-Ellison, systemic mastocytosis, multiple endocrine adenoma syndrome)
Gastroesophageal reflux disease (GERD)
Domepridone is indicated for the relief of the symptoms of nausea and vomiting. Domeperidone should be used at the lowest effective dose for the shortest duration necessary to control nausea and vomiting. It is recommended to take oral domperidone tablets before meals.
amiodarone.
antacids (e.g., magnesium hydroxide, calcium carbonate; within 2 hours of taking ranitidine)
"azole" antifungals (e.g., itraconazole, ketoconazole, posaconazole)
cefuroxime.
clavulanic acid.
cyclosporine.
delavirdine.
dexmethylphenidate.
Bepridil.
Cisapride.
Darunavir.
Dronedarone.
Fluconazole.
Ketoconazole.
Levoketoconazole.
Mesoridazine.
Do not chew, crush or break it. Cyclotab Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Cyclotab Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Cyclotab Tablet helps relieve acidity and heartburn.
It is a well tolerated and safe medicine with very low incidence of side effects.
It should be taken before meals as per the dose and duration prescribed by your doctor.
Avoid taking soft drinks, citrus fruits like orange and lemon while taking this medicine. These can irritate the stomach and increase acid secretion.
It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Cyclotab Tablet as it may irritate your stomach and also cause excessive drowsiness.
Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cyclotab Tablet is to be taken empty stomach.
Q. What are the instructions for storage and disposal of Cyclotab Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. What is the best time to take Cyclotab Tablet?
Take Cyclotab Tablet exactly as directed by your doctor. It can be taken with or without food. To prevent heartburn and acid indigestion, take it 30-60 minutes before eating food or drinking beverages as that can lead to indigestion. Follow all directions as advised.
Q. What are the serious side effects of an overdose of Cyclotab Tablet?
Serious side effects are rare but can occur if you take a higher than the recommended dose. You could have stomach pain that seems to be getting worse (sign of an inflamed liver or pancreas), back pain, fever, pain while peeing or blood in your urine (signs of kidney problems), rash and a slow or irregular heartbeat.
Q. Can the use of Cyclotab Tablet cause dryness in mouth?
Yes, the use of Cyclotab Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.
