Manufacturer: Roche Products India Pvt Ltd
Salt Composition : Ganciclovir(500mg)
Cymevene 500mg Injection is administered as an injection by a healthcare professional. Kindly do not self-administer. It is given by slow intravenous (IV) infusion over a 1-hour period to avoid damage to the kidneys. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage.
The primary mechanism of ganciclovir action against CMV is inhibition of the replication of viral DNA by ganciclovir-5'-triphosphate (ganciclovir-TP). This inhibition includes a selective and potent inhibition of the viral DNA polymerase
Little to no metabolism, about 90% of plasma ganciclovir is eliminated unchanged in the urine. Renal excretion of unchanged drug by glomerular filtration and active tubular secretion is the major route of elimination of ganciclovir. 2.5 to 3.6 hours (mean 2.9 hours) when administered intravenously in adults
Vomiting
Nausea
Injection site reaction
Increased liver enzymes
GANCICLOVIR INJECTION is contraindicated in patients who have experienced a clinically significant hypersensitivity reaction (e.g., anaphylaxis) to ganciclovir, valganciclovir or acyclovir. patients with pre-existing cytopenias and in patients receiving myelosuppressive drugs or irradiation
Cymevene 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Cymevene 500mg Injection. Please consult your doctor.
Cymevene 500mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Treatment of CMV Retinitis. ...
Prevention of CMV Disease in Transplant Recipients. ...
Impairment of Fertility. ...
Fetal Toxicity. ...
Mutagenesis and Carcinogenesis. ...
Geriatric Use. ...
Renal Impairment.
Amoxicillin Ganciclovir may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Amphetamine Amphetamine may decrease the excretion rate of Ganciclovir which could result in a higher serum level.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Cymevene 500mg Injection, consult your doctor.
Consult a doctor before taking any medicines
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Cymevene 500mg Injection effective?
Cymevene 500mg Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Cymevene 500mg Injection too early, the symptoms may return or worsen.
Q. How is Cymevene 500mg Injection administered?
Cymevene 500mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Cymevene 500mg Injection.
Q. Is Cymevene 500mg Injection safe?
Cymevene 500mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. What should I tell my doctor before starting treatment with Cymevene 500mg Injection?
Before starting treatment with Cymevene 500mg Injection, tell your doctor if you have any other health problems, like kidney or liver-related issues. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Consult your doctor if you are planning a baby, if you are pregnant or breastfeeding, before starting treatment with Cymevene 500mg Injection to avoid any harmful effects on the baby.
