Manufacturer: Ozone Pharmaceuticals Ltd
Salt Composition : Methylcobalamin(1000mcg), Niacinamide(100mg), Vitamin B6(Pyridoxine)(100mg)
Vial of 2ml Injection
(Inclusive of all taxes)
Cynocal-16 RF Injection is administered under the supervision of a healthcare professional. Do not self-administer this injection. Inform your doctor if you have any known allergies to this medication.
Methylcobalamin is an active form of vitamin B12, and a coenzyme of methionine synthase, which is required for DNA and protein methylation. In addition, methylcobalamin facilitates neurite outgrowth and inhibits neural apoptosis through the Erk1/2 and Akt signaling pathways.
Vitamin B6 plays an important role in the body. It is needed to maintain the health of nerves, skin, and red blood cells. Pyridoxine has been used to prevent or treat a certain nerve disorder (peripheral neuropathy) caused by certain medications
Within a complex metabolic system niacinamide controls the NFκB-mediated transcription of signalling molecules by inhibiting the nuclear poly (ADP-ribose) polymerase-1 (PARP-1). Niacinamide is a well-tolerated and safe substance often used in cosmetics.
Methylcobalamin can be administered orally, parenterally and intranasal. Methylcobalamin binds with an intrinsic factor and form a complex which is absorbed in distal ileum. Its half life is 6 days.
There is no indication of circadian rhythm in vitamin B6-levels in blood plasma. Pharmacokinetics of vitamin B6 differ fundamentally, depending from the route of administration. The rate constants of elimination of B6-metabolites indicate a tendency of accumulation. Pyridoxine is rapidly metabolized in erythrocytes
Nicotinamide, the amide form of vitamin B3 (niacin), has long been associated with neuronal development, survival, and function in the central nervous system (CNS), being implicated in both neuronal death and neuroprotection.
No common side effects seen
low amount of potassium in the blood.
Leber's hereditary optic atrophy.
inflammation of the stomach called atrophic gastritis.
past history of complete removal of stomach
suicidal thoughts.
depression.
The only two contraindications for vitamin B6 are hypervitaminosis B6, as toxic levels may cause sensory neuropathy and hypersensitivity to pyridoxine
diabetes.
a type of joint disorder due to excess uric acid in the blood called gout.
increased risk of bleeding due to clotting disorder.
a sudden worsening of heart related chest pain called angina.
low blood pressure.
bleeding from an artery.
an ulcer from too much stomach acid.
Information regarding the use of Cynocal-16 RF Injection during pregnancy is not available. Please consult your doctor.
Caution is advised when consuming alcohol with Cynocal-16 RF Injection. Please consult your doctor.
Cynocal-16 RF Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
MeCbl is now prescribed for the treatment of vitamin B12 deficiency and is slowly replacing the traditional B12 formulations like cyanocobalamin and hydroxocobalamin. MeCbl is essential for the normal functioning of the brain and nervous system and the formation of blood
Vitamin B6 is indicated in cases of its deficiency, which may be due to poor renal function, autoimmune diseases, increased alcohol intake, or isoniazid, cycloserine, valproic acid, phenytoin, carbamazepine, primidone, hydralazine, and theophylline therapy
People use niacinamide to prevent vitamin B3 deficiency and related conditions such as pellagra. It is also used for acne, diabetes, cancer, osteoarthritis, aging skin, skin discoloration, and many other conditions, but there is no good scientific evidence to support most of these uses.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Cynocal-16 RF Injection, please consult your doctor.
Consult a doctor before taking any medicines
Cynocal-16 RF Injection helps treat vitamin B deficiency.
Inform your doctor if you are also taking medication for parkinson’s disease such as levodopa.
Inform your doctor if you are pregnant or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What is Cynocal-16 RF Injection?
Cynocal-16 RF Injection is a combination of three medicines: Nicotinamide, Cynacobalamin, and Folic acid. This medicine is used for treating or preventing vitamin deficiency. Deficiency of vitamins may cause anemia and other nerve problems.
Q. What is Vitamin deficiency anemia?
Vitamin deficiency anemia is a lack of healthy red blood cells caused when you have lower than normal amounts of certain vitamins. Vitamins whose deficiency leads to vitamin deficiency anemia include folic acid, vitamin B-12, and vitamin C. Vitamin deficiency anemia can also occur if your body has trouble absorbing or processing the vitamins. Vitamin deficiency anemia can usually be corrected with vitamin supplements and by making changes to your diet.
